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ScienceDirect - Psychoneuroendocrinology : Direct radioimmunoassay of cortisol in saliv... - 0 views

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    dexamethasone suppression test supports the use of salivary cortisol testing.
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The Diagnostic Applications of Saliva- A Review - 0 views

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    Fantastic article on the review of the clinical use of saliva testing.  Of note, is the extensive documentation of the validation studies of hormone saliva testing.  Clearly, if a physician is against saliva testing, it is because of a lack of knowledge on the subject.
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Nighttime salivary cortisol: a useful test for the... [J Clin Endocrinol Metab. 2002] -... - 0 views

  • Salivary cortisol measurements worked as well as plasma measurements and better than urine glucocorticoid excretion. We concluded that bedtime salivary cortisol measurement is a practical and accurate screening test for the diagnosis of Cushing's syndrome.
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    Cortisol Salivary testing shown to be test of choice for diagnosis of Cushing's syndrome
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Diagnosing Growth Hormone Deficiency in Adults - 0 views

  • it is clear that serum IGF-1 and or IGFBP-3 can be normal in patients with undisputed GHD
  • Various investigators have reported normal IGF-1 values in 37–70% of GH deficient adults
  • The co-administration of arginine and GHRH (the combined test) is a powerful stimulus for GH production and has gained increasing acceptance as a useful method of diagnosing GHD [34]. This test has been advocated as a suitable alternative to ITT
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  • The glucagon stimulation test (GST) is a reliable, safe alternative to the ITT in the diagnosis of GHD
  • It has also been suggested that that even mildly increased BMI (25–30 kg/m2) can result in diminished stimulated GH production in 13% of healthy subjects
  • Obesity, particularly marked obesity, is associated with blunted GH secretion in response to provocative stimuli
  • An intravenous infusion of arginine (0.5 g/kg body weight) together with an intravenous bolus of GHRH (1 mcg/kg body weight) is administered [30]. Serum samples for GH are then obtained every 15–30 minutes for two hours.
  • GH levels are higher during the luteal phase in comparison with the follicular phase of the cycle
  • Corneli et al. have defined BMI-specific cut-off points for diagnosing adult-onset GHD using GHRH + arginine—11.5 ng/mL for those with BMI < 25 kg/m2, 8.0 ng/mL for BMI 25–30 kg/m2, 4.2 ng/mL for those with BMI > 30 kg/m2
  • Oral, in contrast to transdermal oestrogen, lowers IGF-1 levels and is associated with increased GH levels
  • Adequate pituitary replacement with thyroxine and hydrocortisone are needed for optimal GH production
  • one cannot rely on a low IGF-1 to diagnose GHD in women taking oral oestrogen preparations.
  • Numerous GH secretagogues are available with the insulin tolerance test being the gold standard and the glucagon stimulation test or the GHRH + arginine as acceptable alternatives
  • ain et al. found the GST to be at least as good as the ITT in provoking GH secretion
  • the GST is safe, with almost no contraindications, it causes nausea and sometimes vomiting in 15–20% of subjects
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    Nice, more recent analysis, of HGH testing.
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A Vitamin B-12 Supplement of 500 μg/d for Eight Weeks Does Not Normalize Urin... - 0 views

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    current vitamin B12 recommendations are too low.  Proper vitamin B12 biomarker testing reveals this fact. The problem is most people fall prey to the lack of knowledge behind simple serum levels.  Simple B12 serum levels are woefully inadequate. Insurance would rather one stay with inadequate testing to save money, rather than actually read the science to learn about new testing.
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Simultaneous determination of salivary testosterone and dehydroepiandrosterone using LC... - 0 views

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    salivary testosterone and DHEA using LC-MS/MS accuracy exceeds 98.5%.  Compare that with historical 50% resolution of pain with a hysterectomy.  There is no perfect test, but if accuracy exceeds 98%, you have  reliable test.
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North Korea missile exploded shortly after lift-off: Seoul - Locality News - 0 views

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      North Korea tested a Musudan missile, which is capable of hitting US bases as far away as Guam. Seoul: An outburst almost immediately after takeoff was behind the failure of North Korea’s latest test-firing of a powerful medium-range missile, the South Korean military established on Monday. North Korea tested a Musudan missile - which ...
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Late-night salivary cortisol in normal subjects and in patients with Cushing's syndrome... - 1 views

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    specificity of saliva/salivary cortisol testing for Cushing's syndrome is 100%; but sensitivity was 69%.  testing not done via LC-MS which is the gold standard.  This could explain the low sensitivity as compared to other studies.
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Hypocortisolism: An Evidence-based Review - 1 views

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    Fantastic review of the literature as it relates to hypocortisolism. This paper reviews the various proposed pathophysiologic mechanisms for the development of hypocortisolism. It also discusses the proper diagnostic test of choice: salivary cortisol testing.
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The Diagnosis of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline - 0 views

  • late night salivary cortiso
  • high diagnostic accuracy
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    salivary cortisol testing recommended as first-line test for Cushing's syndrome due to "high diagnostic accuracy".  So, I wonder why so many state medical boards and insurance companies have missed this one?
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Human saliva as a diagnostic specimen. [J Nutr. 2001] - PubMed result - 0 views

  • Saliva can be used as a diagnostic specimen not only to obtain information more inexpensively and efficiently than serum, but also to provide information not readily available from serum testing.
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    saliva testing validated for diagnostic testing
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Overnight dexamethasone suppression test: comparis... [Eur J Endocrinol. 1996] - PubMed... - 0 views

  • In conclusion we recommend the overnight dexamethasone suppression test with measurement of salivary cortisol as a screening test for Cushing's syndrome.
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    saliva testing of cortisol preferred for screening for Cushing's syndrome
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Alt/Trad Medical Review - 0 views

  • Vitamin C interferes with several glucose tests, including tests diabetics use at home. U
  • rinary glucose test strips will test false positive with as little as 2,000mg of vitamin C daily
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    Vitamin C will induce false positives on glucose test strips

Sleep Apnea Test That Can Be Done at Home - 2 views

started by Meredith Blige on 21 Jun 11 no follow-up yet
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Which Patients Do Not Require a GH Stimulation Test for the Diagnosis of Adult GH Defic... - 0 views

  • Four studies have reported that the probability of GHD (peak GH criteria ranging from < 2.3 to < 5 μg/liter) in patients with three to four PHDs ranges from 91% to 100%
  • 95% accuracy by the presence of either three or more PHDs or a serum IGF-I concentration less than 84 μg/lite
  • adult GHD could be predicted with 95% accuracy by the presence of either three or four PHDs or a serum IGF-I concentration less than 84 μg/liter
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  • Hypopituitary adults with GHD have been reported to have normal serum IGF-I levels in 37–70% of patients in various studies (5, 9, 18, 21, 22). This is owing in part to the fact that multiple factors regulate serum IGF-I concentrations including nutritional status; hepatic and renal function; and circulating concentrations of thyroid hormone, androgens, and estrogens
  • changes in concentrations of IGF-binding proteins (IGFBPs) influence the total concentration of IGF-I in plasma
  • Among patients with an IGF-I sd score above −1 in the present study, 46% had a peak GH less than 2.5 μg/liter and 67% had a peak GH less than 5 μg/liter.
  • In summary, adult GHD can be predicted with 95% accuracy by the presence of either three or four PHDs or a serum IGF-I concentration less than 84 μg/liter
  • We propose that adult patients with three or four PHDs (three or four of the following deficiencies: TSH, ACTH, gonadotropins [LH and/or FSH], and AVP [central diabetes insipidus]) do not require a GH stimulation test to make the diagnosis of adult GHD
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    Insulin Tolerance Test is the gold standard for HGH diagnosis, but this an unpopular Test do to long list of side effects.  This study finds a 95% accuracy for IGF-1 less than 84 with 3 or more coexisting pituitary hormone deficiencies.
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Blood Test at Home - 0 views

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    We offer the full range of blood test at home with results available as early as 48 hours. Mobile Phlebotomy offered for blood sample collection.
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LeanBiome™ (Official) | Get Save UpTo $540 Today Only! - 0 views

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    LeanBiome™ (Official) | Get Save UpTo $540 Today Only! usleanbiome.com LeanBiome™ Hurry Up! Offer Expires in: 00 HOUR 29 MINUTE 59 SECOND LeanBiome Attention! Get Special 84% Discount Today Faster fat burning and weight loss Healthy cholesterol and sugar levels Higher energy levels Regular price: $129 Only for: 39$ What Is LeanBiome? LeanBiome Lean for Good is a weight loss dietary supplement derived from scientifically researched ingredients and comprehensively developed to help people achieve sustainable weight control. The formula comes in a capsule format that is easy to take and is made with natural ingredients from plants and other sources to achieve its goals. The main ingredient in LeanBiome is piperine, which has been found to affect the body's ability to absorb micronutrients and other compounds more effectively. LeanBiome is a dietary supplement that claims to help weight management. It contains 100% natural ingredients that support healthy weight loss. It does not interfere with any natural process making it safe for use. It ranks among the top weight loss supplements that claim to provide a permanent solution. LeanBiome is made by a company named Lean for Good. It is made with natural and research-backed ingredients that help you lose excess fat without hassles. It is sold in capsule form. The company assures the composition is GMO, gluten, and soy-free. As for manufacturing standards, you need not fret. The company makes the supplement in a facility certified by the FDA. How Does LeanBiome Work? The starting period of the LeanBiome program includes a detoxification process that effectively removes any accumulated ree radicals, toxins, fand oxidative stress. This cleansing enables improved blood circulation, setting the stage for the body to initiate its own fat-burning mechanisms. To enhance metabolic activity, introducing the lean bacteria contained in LeanBiome to your gut microbiome is a beneficial approach. This activation triggers r
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Dr. Ajay Kaul India in Favor of a Test for Aortic atresia, Raise your Hand - 0 views

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    For at least the past two decades, Dr. Ajay Kaul India said, he and his colleagues have included the thumb-palm test in lectures to medical students and used the test for patients who might be at risk of carrying atresia. Dr. Ajay Kaul Phone No.: +91-9370586696 Email: drajaykaul@indiacardiacsurgery.com
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Neurotransmitters excreted in the urine as biomarkers of nervous system activity: Valid... - 0 views

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    article discusses testing of neurotransmitters in urine specimens. Both the clinical usefulness, and pros/cons of urine testing for neurotransmitters
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Diagnostic Potential of Saliva: Current State and Future Applications - 0 views

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    saliva testing is the new "gold standard" for hormone evaluation.  No testing method is perfect and thus there are guidelines for salivary collections.  However, saliva is equal too or superior to blood for hormone evaluation.
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