Skip to main content

Home/ Dr. Goodyear/ Group items matching "fatty" in title, tags, annotations or url

Group items matching
in title, tags, annotations or url

Sort By: Relevance | Date Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

ω-3 Fatty Acid Supplementation as a Potential Therapeutic Aid for the Recovery from Mild Traumatic Brain Injury/Concussion - 0 views

advances.nutrition.org/...268.full

omega 3 DHA EPA fish oil TBI traumatic brain injury concussions concussion brain injury

shared by Nathan Goodyear on 30 Aug 15 - No Cached
  • There is a growing body of preclinical literature suggesting that ω-3 FAs, and DHA in particular, may play a therapeutic role in mTBI
  • the potential for ameliorating or possibly even preventing the complications associated with concussions
  • DHA is the predominant ω-3 FA present in the brain, and, consistent with this finding, DHA, and not EPA, has been demonstrated to be critical for brain development and cognitive function throughout life
  • ...7 more annotations...
  • the concentration of EPA in the brain is negligible (77–80), suggesting that EPA plays a limited role in mediating the beneficial effects of LCPUFA supplementation on mTBI pathology
  • the current state of the science regarding LCPUFA supplementation for the treatment of concussion is based primarily on animal models
  • there is evidence that the amount of DHA in brain tissue is decreased after mTBI (65, 66), suggesting an elevated need for DHA in mTBI recovery.
  • the well-established role of DHA in supporting the structure and function of the brain throughout the lifespan (26, 27, 46, 47, 53) provides encouragement that LCPUFAs may also prove beneficial in the context of concussion recovery.
  • no therapies are currently available to aid the recovery from this injury
  • Previously discussed reports outlining the use of ω-3 FAs in the recovery from severe TBIs (reviewed in Ref. 92) described the use of very-high doses of LCPUFAs (16.2 g/d EPA plus DHA) in the recovery of these patients
  • Within the context of mTBIs/concussions, translating a DHA intake used in several rat studies of mTBI recovery (40 mg ⋅ kg−1 ⋅ d−1 DHA) (57, 63, 64) using body surface area conversion methods (93) amounts to an estimated human intake of 387 mg/d DHA
  • Nathan Goodyear on 30 Aug 15
     
    nice review of the evidence of n-3, particularily DHA, in concussions and concussion recovery.
Nathan Goodyear

Dietary Supplementation With the Omega-3 Fatty Acid Docosahe... : Neurosurgery - 0 views

journals.lww.com/...with_the_omega_3_fatty.31.aspx

brain injury brain TBI traumatic brain injury DHA

shared by Nathan Goodyear on 31 Aug 15 - No Cached
  • Nathan Goodyear on 31 Aug 15
     
    Animal study finds pre-emptive DHA at 40 mg/kg reduced injury response during medically induced TBI.  Not only can DHA be used with TBI, but this study suggests it can be used in a prevention mode.
Nathan Goodyear

Omega Research - 0 views

www.omega-research.com/researchview.php

Omega-3 vitamin C E antioxidants oxidative stress infertility

shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • These data have important implications for the supplementation of a combination of omega-3 fatty acids and antioxidants in the successful management of female infertility.
  • Nathan Goodyear on 15 Dec 10
     
    omega 3 and antioxidants aid in infertility
Nathan Goodyear

Dietary factors and growth and metabolism in experimental tumors - 0 views

www.jnutbio.com/...abstract

omega-6 inflammation tumor cancer dietary

shared by Nathan Goodyear on 10 Feb 11 - No Cached
  • Linoleic acid (LA), an essential n-6 polyunsaturated fatty acid (PUFA), was identified as an agent in dietary fat that is responsible for an up-regulation of tumor growth in vivo
  • Nathan Goodyear on 10 Feb 11
     
    High omega-6 intake in diet increases tumor growth
Nathan Goodyear

The Effect of Dietary Supplementation with n-3 Polyunsaturated Fatty Acids on the Synthesis of Interleukin-1 and Tumor Necrosis Factor by Mononuclear Cells - NEJM - 0 views

www.nejm.org/...NEJM198902023200501

Omega-3 inflammation anti-inflammatory

shared by Nathan Goodyear on 11 Feb 11 - No Cached
  • Nathan Goodyear on 11 Feb 11
     
    Omega-3 is anti-inflammatory
Nathan Goodyear

(n-3) Fatty Acids and Cancer Therapy - J. Nutr. - 0 views

jn.nutrition.org/...3427S.abstract

Omega-3 cancer

shared by Nathan Goodyear on 11 Feb 11 - No Cached
  • Used alone, an (n-3) supplement may be a useful alternative therapy for patients who are not candidates for standard toxic cancer therapies.
  • Nathan Goodyear on 11 Feb 11
     
    Omega-3 reduce inflammation, inhibit tumor growth, inhibit angiogenesis, induce cancer cell death, and inhibit estrogen signaling
Nathan Goodyear

Effect of dietary GLA+/−tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts - Kenny - 2001 - International Journal of Cancer - Wiley Online Library - 0 views

onlinelibrary.wiley.com/...pdf

GLA breast cancer estrogen receptor positive tamoxifen

shared by Nathan Goodyear on 11 Feb 11 - No Cached
  • Nathan Goodyear on 11 Feb 11
     
    GLA enhances the effectiveness of tamoxifen in the treatment of ER + breast cancer
Nathan Goodyear

Dietary supplementation with eicosapentaenoic and ... [Int J Cancer. 1998] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...9495237

Omega-3 DHA EPA cancer

shared by Nathan Goodyear on 11 Feb 11 - No Cached
  • t is concluded from the results of the present study that the anti-tumoral effect of EPA is related mainly to its inhibition of cell proliferation, whereas that of DHA corresponds with its induction of apoptosis. The alterations in fatty-acid composition induced by EPA or DHA appear to be factors underlying their differential actions on cell proliferation and apoptosis.
  • Nathan Goodyear on 11 Feb 11
     
    Omega-3, DHA and EPA, work differently in their anti-cancer effects
Nathan Goodyear

Arch Intern Med -- Abstract: Effect of Different Antilipidemic Agents and Diets on Mortality: A Systematic Review, April 11, 2005, Studer et al. 165 (7): 725 - 0 views

archinte.ama-assn.org/...725

Omega-3 fish oil lipids cholesterol

shared by Nathan Goodyear on 15 Feb 11 - No Cached
  • Statins and n-3 fatty acids are the most favorable lipid-lowering interventions with reduced risks of overall and cardiac mortality.
  • Nathan Goodyear on 15 Feb 11
     
    Omega-3 most favorable lipid lowering agent
Nathan Goodyear

Docosahexaenoic Acid but Not Eicosapentaenoic Acid Lowers Ambulatory Blood Pressure and Heart Rate in Humans -- Mori et al. 34 (2): 253 -- Hypertension - 0 views

hyper.ahajournals.org/...253

docosahexaenoic Omega-3 blood pressure heart rate

shared by Nathan Goodyear on 15 Feb 11 - No Cached
  • The results of this study suggest that DHA is the principal 3 fatty acid in fish and fish oils that is responsible for their BP- and HR-lowering effects in humans.
  • Nathan Goodyear on 15 Feb 11
     
    Omega-3, DHA lowers pressure and heart rate
Nathan Goodyear

Cell - GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects - 0 views

www.cell.com/...S0092-8674(10)00888-3

Omega-3 DHA EPA insulin resistance Diabetes

shared by Nathan Goodyear on 15 Feb 11 - No Cached
  • ω-3 FA receptor/sensor and mediates potent insulin sensitizing and antidiabetic effects in vivo
  • Nathan Goodyear on 15 Feb 11
     
    Omega-3 improves insulin sensitivity
Nathan Goodyear

The clinical efficacy of the adipocyte-derived hor... [Arch Physiol Biochem. 2006] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...16931453

leptin glucose metabolism dyslipidemia fatty liver elevated cholesterol

shared by Nathan Goodyear on 10 Mar 11 - No Cached
  • In hypoleptinemic patients with lipodystrophy, there is a dramatic improvement in glucose metabolism, dyslipidemia and hepatic steatosis
  • Nathan Goodyear on 10 Mar 11
     
    leptin helps to correct metabolic dysfunction
Nathan Goodyear

ingentaconnect Immunonutrition in Surgical Patients - 0 views

www.ingentaconnect.com/...art00009

immunonutrition surgery surgical patients

shared by Nathan Goodyear on 21 Mar 11 - No Cached
  • Surgery induces an inflammatory response
  • A range of nutrients, including several amino acids, antioxidant vitamins and minerals, ω-3 fatty acids, and nucleotides, are able to modulate inflammation and the associated oxidative stress, and maintain or improve immune function
  • parenteral glutamine is recommended in patients receiving parenteral nutrition
  • ...2 more annotations...
  • Antioxidants, particularly selenium, should be considered for critically ill patients
  • enteral formulas enriched with fish oils are recommended for patients with acute respiratory distress syndrome.
  • Nathan Goodyear on 21 Mar 11
     
    nutrition to improve inflammation in surgical patiens
Nathan Goodyear

Mechanism of Human SIRT1 Activation by Resveratrol - 0 views

www.jbc.org/...17187.short

Resveratrol SIRT1

shared by Nathan Goodyear on 18 Mar 11 - No Cached
  • The NAD+-dependent protein deacetylase family, Sir2 (or sirtuins), is important for many cellular processes including gene silencing, regulation of p53, fatty acid metabolism, cell cycle regulation, and life span extension
  • resveratrol was shown to increase life span in three model organisms through a Sir2-dependent pathway.
  • Nathan Goodyear on 18 Mar 11
     
    Resveratrol potentially increases life span through SIRT1 activation
Nathan Goodyear

Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic fatty rats - Agil - 2010 - Journal of Pineal Research - Wiley Online Library - 0 views

onlinelibrary.wiley.com/...abstract

obesity weight loss melatonin LDL HDL

shared by Nathan Goodyear on 27 May 11 - No Cached
  • Nathan Goodyear on 27 May 11
     
    melatonin appears to help in weight loss and improve LDL and HDL cholesterol levels
Nathan Goodyear

SpringerLink - Diabetologia, Volume 42, Number 2 - 0 views

www.springerlink.com/...l50vrq37getytvjw

fatty acids saturated fats glucose insulin

shared by Nathan Goodyear on 27 May 11 - No Cached
  • Nathan Goodyear on 27 May 11
     
    The type of fat you eat can increase the insulin response to glucose.  For example, saturated fats + glucose  promote a larger insulin response than does glucose alone.
Nathan Goodyear

Polyunsaturated fatty acids inhibit hepatic stearo... [Lipids. 1996] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...8729090

Omega-3 SCD stearoyl-CoA desaturease obesity weight gain

shared by Nathan Goodyear on 27 May 11 - No Cached
  • Nathan Goodyear on 27 May 11
     
    Poly-unsaturated fats, particularily Omega-3, blocks SCD activity
Nathan Goodyear

Hormonal and metabolic effects of polyunsaturated fatty acids in young women with polycystic ovary syndrome: results from a cross-sectional analysis and a randomized, placebo-controlled, crossover trial - 0 views

www.ajcn.org/...652.abstract

metabolic syndrome Omega-3 PCOS

shared by Nathan Goodyear on 09 May 11 - No Cached
  • n−3 PUFAs improves androgenic profiles in PCOS
  • Nathan Goodyear on 09 May 11
     
    omega shown to reduce androgens in women with PCOS
Nathan Goodyear

Anti-obesity effects of green tea: from bedside to... [Mol Nutr Food Res. 2006] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...16470636

obesity weight loss green tea extract

shared by Nathan Goodyear on 05 May 11 - No Cached
  • Green tea, green tea catechins, and epigallocatechin gallate (EGCG) have been demonstrated in cell culture and animal models of obesity to reduce adipocyte differentiation and proliferation, lipogenesis, fat mass, body weight, fat absorption, plasma levels of triglycerides, free fatty acids, cholesterol, glucose, insulin and leptin, as well as to increase beta-oxidation and thermogenesis.
  • Studies conducted with human subjects report reduced body weight and body fat, as well as increased fat oxidation and thermogenesis and thereby confirm findings in cell culture systems and animal models of obesity
  • Nathan Goodyear on 05 May 11
     
    Green tea and Green tea extract aid in many areas of weight loss
« First ‹ Previous 141 - 160 of 189 Next › Last »
Showing 20▼ items per page