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Vitamin D3 shown to reduce CRP, TNF, IL-6, IL-1B, IL-8 in colorectal adenoma patients. This study supports the anti-inflammatory, anti-cancer benefits of vitamin D3.

sespquiterpenes show anti-inflammatory and anti-cancer effects.

Very nice study.  The authors looked at normal prostate, early disease and late stage prostate cancer.  The authors found that ER beta expression, as a general rule, was lost as progression occurred to the high-grade dysplasias and grad 4/5 carcinomas of the prostate.  Early low/moderate dysplasia was associated with an increase in ER beta--the authors propose that this was due to an attempt of the basal epithelium to counter the paracrine effect of ER alpha.   In contrast, androgen receptors appeared to be equally expressed across all.

Artesunate induces apoptosis in esophageal cell lines.

ART inhibited breast cancer cell proliferation via a reactive oxygen species (ROS)-dependent G2/M arrest and ROS-independent G1 arrest. ART-treated MDA-MB-468 and SK-BR-3 cells also experienced apoptotic cell death, which was both ROS- and iron-dependent. ART-induced oxidative stress caused the loss of mitochondrial outer membrane integrity and damage to the cellular DNA of MDA-MB-468 and SK-BR-3 cells. Only abstract available...I will post full article once available.

Review of the targeted effects of CBDA CBD and THC in cancer treatment

Great review of androgen dependent and androgen independent prostate cancer.

This article describes the underlying transcription responses to the anti-inflammatory effects provided through progesterone receptors (PR) in breast cancer.

Great review on the anti-cancer properties of melatonin.  Well referenced.

Very interesting study.  In ER/PR + breast cancer cells, Estradiol and 5alpha-dihydroprogestorone increase the membrane expression of 5alpha-dihydroprogesterone receptors.  This has a pro-growth, pro-metastatic potential.  In contrast, the metabolites 3alpha-dihdroprogesterone and 20alpha-HP inhibit the same membrane receptor expression thus giving an antigrowth, anti-metastatic potential.

Anti-oxidant therapy for cancer patients

Another animal study finds Testosterone plays a role in bladder cancer development.  The study used anti androgen and 5 alpha reductase inhibitor therapy to see if these add on therapies provided anything to ADR whether via castration or pituitary suppression--the answer was no.  The authors concluded that Testosterone played more of a role with AR versus the more active 5alpha-DHT metabolite.

The evidence of probiotics in cancer is limited.  The limited evidence points to an increase in anti-oxidative enzymes i.e. glutathion-S-transferase, glutathione perioxidase, catalase, SOD.

Great early review of peptide therapeutics in cancer. There are anti-microbial peptides (AMPs), cell penetrating peptides (CPPs), and tumor targeting peptides (TTPs)

Incredible review to the evidence of action of artemisinin and its metabolites in cancer: apoptotic, arrest of cell growth, anti-inflammatory, immunomodulation...

Wide benefits of melatonin in the battle against cancer: HIF-1alpha inhibitor, aromatase inhibitory, anti-angiogenesis, triggers apoptosis...

Artesunate has anti-cancer effects.

Melatonin has broad anti-cancer properties.

CBD tops CBG and CBC in anti-breast cancer effects.