Skip to main content

Home/ Dr. Goodyear/ Group items matching "without" in title, tags, annotations or url

Group items matching
in title, tags, annotations or url

Sort By: Relevance | Date Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Higher Free Thyroxine Levels Predict Increased Incidence of Dementia in Older Men: The Health In Men Study - 0 views

  •  
    what a silly study!  They look at free T4, the weakest thyroid hormone and found high levels to be associated with dementia.  However, they failed to assess free T3, the most biologically active, and reverse T3, inactive.  This study was like they intentionally blinded themselves of the body's physiology to study dementia.  This is the problem with a lot of research today: they have forgotten their foundation. Many older adults struggle with poor free T4 to free T3 conversion and high reverse T3 conversion.  So, without knowing what these clients were doing in these pathways makes their conclusion obsolete.
Nathan Goodyear

Treatment of Obesity-Related Complications with Novel Classes of Naturally Occurring PPAR Agonists - 0 views

  •  
    natural PPAR agonists.  Maybe provide some of the anti-inflammatory improved lipid metabolism without the side effects found in their synthetic counterpart avandia
Nathan Goodyear

Xanthohumol, a chalcon derived from hops, ... [Mol Nutr Food Res. 2010] - PubMed - NCBI - 0 views

  •  
    xanthohumol again shows to inhibit NF-kappaB.  This time in individuals with NAFLD and chronic liver disease.  The effect was shwon to be dose dependent, without plateau with dosing up to 50 Mcriomoloar
George Thomas

TPE kills pathogens without toxins - 0 views

  •  
    Plastics News Portal, Plastics Jobs, Plastics Directory And Trade Website for World and India - Plasticsinfomart.com
Nathan Goodyear

Thyrotropin suppression by metformin in a cohort of patients with differentiated thyroid cancer in follow-up - 0 views

  •  
    Again, showing that metformin suppresses TSH secretion without change in actual thyroid hormone levels.  We know that inflammation plays a role in HPA suppression, why not with TSH?
Nathan Goodyear

Thyrotropin Suppression by Metformin - 0 views

  •  
    Metformin shown to suppress TSH secretion without change in free t4 or free t3 levels.  This again, shows the lack of reliability of the test TSH.  With the suppression of TSH indicated in this study, the free t4 and t3 should have been elevated, but were obviously not.
Nathan Goodyear

Mortality and Other Important Diabetes-Related Outcomes With Insulin vs Other Antihyperglycemic Therapies in Type 2 Diabetes - 0 views

  •  
    Insulin therapy in people with type II diabetes shown to increase complications, cancer, and mortality.  The reason?  Insulin is not the problem.  Treat the cause.  Diabetes can not be properly managed without dietary changes and weight loss.
Nathan Goodyear

Brown adipose tissue activity after a high-calorie meal in humans - 0 views

  •  
    Interesting study.  Studies have found brown fat to be thermogenic.  This study found no such association. In fact, a high calorie diet increased glucose uptake by brown fat without resultant thermogenesis.  
Smile Reef

Enjoying Halloween Treats While Ensuring Children's Dental Health - Smile Reef Pediatric Dentistry - 0 views

  •  
    Every child loves Halloween. It's always a fun time to go out in costume and get treats. If they are lucky they are bound to take home a bag full of candy. That is always good for the kids, but bad for their dental health. Taking care of children's dental health can already be a challenge for some without the constant temptation of sweets.
Nathan Goodyear

Telomerase at the intersection of cancer and aging - 0 views

  • The anti-aging role of telomerase has been demonstrated to be largely mediated by its canonical role in elongating telomeres, which prevents the accumulation of critically short telomeres and loss of tissue homeostasis
  • Short telomeres, and subsequent DDR activation, could occur both in cancer and aging
  • increased abundance of short telomeres correlates with higher genomic instability and decreased longevity in various organisms, including mice, zebrafish, and yeast
  • ...15 more annotations...
  • mice deficient for telomerase or for telomere binding proteins are characterized by accelerated age-related defects
  • In humans, short telomeres are considered good indicators of an individual’s health status and correlate with both genetic and environmental factors
  • Although recent findings strongly support the idea that short telomeres drive several age-related diseases 38 we cannot exclude the possibility that in some situations short telomeres may be a consequence of the disease itself.
  • the current view is that telomerase deficiency may contribute to the early steps of cancer development by fueling chromosomal instability, while subsequent activation of telomerase may be necessary to allow tumor growth and tumor progression towards more malignant states
  • telomerase activation can be an early event in cancer, it is not necessary for cancer initiation
  • telomerase can stimulate tumor progression by ensuring maintenance of telomeres above a critically short length, thus preventing induction of cellular senescence or apoptosis
  • Almost all human cancers present activation of telomerase as a hallmark, most likely as a mechanism to allow unlimited cell proliferation of tumor cells
  • recent evidence demonstrated that short telomeres alone could lead to genomic instability and cancer
  • Getting rid of telomerase can also be problematic; the lack of telomerase could lead to increased chromosomal instability, which in turn could be at the basis for cancer initiation when tumor suppressor barriers are bypassed
  • telomerase activation is a potential therapeutic strategy for the treatment of age-related diseases
  • telomerase activation in adult or old mice by means of a gene therapy strategy was shown to be sufficient to improve metabolic fitness, neuromuscular capacity, and prevent bone loss, as well as significantly increase both median and maximum longevity, without increased cancer incidence
  • These studies suggest that telomerase expression could be considered a feasible approach to reverse tissue dysfunction and extend healthy lifespan without increasing cancer incidence
  • humans almost completely lose telomerase activity from somatic tissues in the adulthood
  • a change of paradigm seems to be occurring in telomerase biology, with a switch from viewing telomerase as fueling cancer to reversing aging
  • Telomerase expression in a background of high levels of tumor suppressors or in aged organisms seems to prevent its expected pro-cancer activity and yet it still functions as an anti-aging factor
  •  
    Telomerase activity and longer telomere length is shown to correlated inversely with many chronic diseases of aging.  In contrast, telomerase activity is found to be involved in carcinogenesis.  Increased carcinogenic potential of telomerase activity has not borne out in studies.  In addition, increased CD8 cell activity as a result of telomerase activation will actually decrease carcinogenic potential via NK activation.
Windows Customer Support Number

1-800-485-4057 Windows tech support help (Computers - Software) - 0 views

  •  
    1-800-485-4057 Windows tech support help is the toll free number for Windows technical support, we troubleshoot all the queries and offering a solutions for all the queries in very short periods of time and also without wasting any time, you can also visit our websites as http://technicalsupportnumberforwindows.com/
Nathan Goodyear

Vitamin C Improves Endothelium-Dependent Vasodilation by Restoring Nitric Oxide Activity in Essential Hypertension | Circulation - 0 views

  •  
    vitamin C, in small study in patient with/without hypertension, found to increase endothelial vasodilation via increasing eNOS activity.
Alan Rann

Plastic Surgery Loans- Get Implausible Look with Simple Financial Assistance! - 0 views

  •  
    Plastic Surgery Loans are provided an opportunity to obtain sufficient cash support for your health conscious problems. This cash advance is very helpful to all as they give you a new life and a new meaning to live for so without any second thought apply with us.
Nathan Goodyear

Testosterone treatment and risk of venous thromboembolism: population based case-control study | The BMJ - 0 views

  •  
    Testosterone is great when needed, not doped; but Testosterone is not without risks.  Population case-control study finds increased blood clot risk in first 6 months of Testosterone therapy.  To many variables left unanswered by this study.  
Nathan Goodyear

http://hyper.ahajournals.org/content/hypertensionaha/45/5/874.full.pdf - 0 views

  •  
    study finds alcohol increases blood pressure in those without elevated blood pressure.
Alan Rann

Cosmetic Surgery Loans- Get the Natural Beauty With Surgery Treatment in Easy Manner! - 0 views

  •  
    Cosmetic surgery loans arrange quick and hassle free monetary support to the needy person for meet surgery expenses. These loans scheme is easily available online and you can apply anytime from anywhere in hassle free manner. The loan amount will be deposited applicant's bank account without paperwork.
Windows Customer Support Number

Windows support number 1-800-261-4071 - 0 views

  •  
    Dail our Windows tech support phone number 1-800-261-4071 for a moment arrangement from our best experts, who gives the boundless technical support help. Our professionals will constantly prepared to help you whenever, We finding every one of the issues and resolve every one of the inquiries in a brief time frames Without any challenges. simply dial our windows customers support number 1-800-261-4071 for a moment help, you likewise visit our sites as http://technicalsupportnumberforwindows.com/ computer San Jose
Windows Customer Support Number

Windows support number 1-800-261-4071 - 0 views

  •  
    Just dial our Windows support number 1-800-261-4071 for an urgent need, if you facing any issues regarding Windows software, Levon tech services provides the proper tech support help and troubleshoot all the issues in a very limited time without facing any difficulties.
Windows Customer Support Number

Windows technical support number 1-800-261-4071 - 0 views

  •  
    Dail our Windows support number 1-800-261-4071 for an instant solution from our best technicians, who provides the unlimited tech support help. Our technicians will always ready to assist you at any time, We diagnosis all the issues and resolve all the queries in a short periods of time Without any difficulties. just dial our windows customers support number 1-800-261-4071 for an instant help
Windows Customer Support Number

Windows support number 1-800-261-4071 - 0 views

  •  
    Levon tech services is offers you the best Windows support number 1-800-261-4071 for all our clients who having any issue with your Windows software, We also ensure that your problems can be resolved in the comfort of your home without exposing you to stress and un-certified technicians. call us any time on our Windows technical support phone number 1-800-261-4071, or you can also visit our websites as http://technicalsupportnumberforwindows.com
« First ‹ Previous 41 - 60 of 295 Next › Last »
Showing 20 items per page