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Nathan Goodyear

Four Thrombotic Events Over 5 Years, Two Pulmonary Emboli and Two Deep Venous Thrombosi... - 0 views

journals.sagepub.com/...2324709616661833

VTE Testosterone venous thromboembolism testosterone therapy testosterone replacement therapy

shared by Nathan Goodyear on 30 Jul 17 - No Cached
  • Nathan Goodyear on 30 Jul 17
     
    VTE in man as a result of supra-physiologic Testosterone and high aromatase activity prior to and on anticoagulant therapy.
Nathan Goodyear

http://www.jpagonline.org/article/S1083-3188(15)00211-9/pdf - 0 views

www.jpagonline.org/...pdf

VTE contraception venous thromboembolism clotting

shared by Nathan Goodyear on 08 Sep 17 - No Cached
  • Nathan Goodyear on 08 Sep 17
     
    review of VTE risk in adolescent women on hormonal contraception.  Good review of the clotting cascade as well.  
Nathan Goodyear

Testosterone treatment and risk of venous thromboembolism: population based case-contro... - 0 views

www.bmj.com/bmj.i5968

low T low Testosterone Testosterone Testosterone therapy VTE venous thromboembolism thromboembolism

shared by Nathan Goodyear on 07 Dec 16 - No Cached
  • Nathan Goodyear on 07 Dec 16
     
    Testosterone is great when needed, not doped; but Testosterone is not without risks.  Population case-control study finds increased blood clot risk in first 6 months of Testosterone therapy.  To many variables left unanswered by this study.  
Nathan Goodyear

High D-dimer levels are associated with poor prognosis in cancer patients - 0 views

www.ncbi.nlm.nih.gov/...PMC3409812

cancer D-dimer

shared by Nathan Goodyear on 10 Jul 18 - No Cached
  • a systemic activation of blood coagulation and procoagulant changes in the hemostatic system have frequently been observed in cancer patients, even in the absence of venous thromboembolism
  • Thrombin is a pivotal enzyme in the process of blood coagulation and leads to the conversion of fibrinogen to fibrin, which is the end product of blood coagulation and finally results in the formation of a fibrin clot
  • deposition of fibrin, which has an important role in the formation of tumor stroma and hematogenous spread of tumor cells.
  • ...5 more annotations...
  • The interaction of fibrin, platelets and tumor cells leads to the formation of platelet-fibrin-tumor-cell aggregates that promote endothelial adhesion and metastatic spread, as well as tumor cell growth and tumor cell survival
  • fibrin degradation products have been shown to display strong angiogenic properties
  • D-dimer is a biomarker that globally indicates the activation of hemostasis and fibrinolysis
  • It is a degradation product of fibrin
  • high D-dimer levels were reported to be predictive of the occurrence of VTE in cancer patients
  • Nathan Goodyear on 10 Jul 18
     
    elevated D-Dimer associated with poor prognosis in cancer. Good review of cancer and ehmostasis.
Nathan Goodyear

Risk of Venous Thromboembolism in Men Receiving Testosterone Therapy - Mayo Clinic Proc... - 0 views

www.mayoclinicproceedings.org/...fulltext

testosterone therapy testosterone replacement therapy DVT PE VTE venous thromboembolism testosterone

shared by Nathan Goodyear on 30 Jul 17 - No Cached
  • Nathan Goodyear on 30 Jul 17
     
    Venous thromboembolism found not be associated with prior Testosterone therapy in men.
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