paroxetine, SSRI, shown to improve depressive symptoms without altering kynurenine levels. Revealing underlying issue of depression in many individuals is disordered tryptophan metabolism due to inflammation
increasing serotonin, in those with PTSD, increases hippocampal volume and memory. In this study, they used Paxil. Why not just give 5-HTP to raise serotonin?
Paxil is estrogen receptor agonist. What is interesting about this is that the FDA just approved this as a non-hormonal way to reduce hot flashes--but it is paxil under a different name. It is non-hormonal--yeah right. The organization making the approval doesn't know what they are doing at worse, or like the IOM stated are not up with the latest scientific knowledge.