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Nathan Goodyear

Comparisons of normal saline and lactated Ringer's resuscitation on hemodynamics, metab... - 0 views

www.ncbi.nlm.nih.gov/...PMC4029282

IV fluids lactated ringers normal saline LR NS

shared by Nathan Goodyear on 03 Jul 18 - No Cached
  • NS contains 154 mM Na+ and Cl-, with an average pH of 5.0 and osmolarity of 308 mOsm/L.
  • LR solution has an average pH of 6.5, is hypo-osmolar (272 mOsm/L), and has similar electrolytes (130 mM Na+, 109 mM Cl-, 28 mM lactate, etc.) to plasma
  • hyperchloremic acidosis
  • ...26 more annotations...
  • LR’s acid base balance is superior to that of NS’s
  • There were no significant differences between LR and NS groups in fibrinogen concentrations or platelet count
  • Total protein dropped
  • no significant differences in Hct (Table  1) or total protein between LR and NS groups
  • Bicarbonate HCO3- levels were decreased by hemorrhage but returned to pre-hemorrhage values by 3 h after LR resuscitation, whereas no return was observed with NS resuscitation
  • Na+ was increased after NS resuscitation
  • No changes in Na+ or K+ were observed
  • K+ did not change initially after NS resuscitation but was elevated at 6 h afterwards
  • Ca++ was similarly decreased
  • Cl- was elevated for 6 h after NS resuscitation, with no changes shown after LR resuscitation
  • PT was similarly prolonged by resuscitation with LR (from 11.2 ± 0.2 sec at baseline to 12.1 ± 0.2 sec at 6 h) and NS
  • Plasma aPTT was also similarly prolonged by resuscitation with LR (from 17.1 ± 0.5 sec baseline to 20.1 ± 1.2 sec at 6 h) or NS
  • NS resuscitation resulted in better oxygen delivery and oxygen delivery-to-oxygen demand ratio as an index of oxygen debt
  • NS had better tissue perfusion and oxygen metabolism than LR
  • LR resuscitation returned BE and bicarbonate to pre-hemorrhage levels within 3 h, but no return of BE or bicarbonate was observed for 6 hr with NS resuscitation
  • current blood bank guidelines state that LR should not be mixed with blood to prevent the risk of clot formation from calcium included in LR
  • LR resuscitation should not be given with blood through the same iv-line and crystalloids should be avoided in patients with blood transfusion
  • PT and aPTT were prolonged for 6 h after hemorrhage and resuscitation, suggesting a hypocoagulable states
  • potential thrombotic risk from LR resuscitation is unlikely.
  • we suspected that the blood pressure after NS resuscitation would be lower than that of LR due to its vasodilator effects
  • NS required a larger resuscitation volume and was associated with poor acid base status and elevated serum potassium in this model
  • NS required 50% more volume and was associated with a higher cardiac output and lower peripheral resistance, as compared to LR resuscitation
  • These differences are possibly due to the vasodilator effects from NS
  • an elevation of K+ was observed at 6 h post NS resuscitation, while no change of K+ was observed after LR resuscitation
  • The mechanism for the increase of K+ from NS is not fully known
  • NS is associated with vasodilator effects and the risks of metabolic acidosis and hyperkalemia
  • Nathan Goodyear on 03 Jul 18
     
    LR vs NS crystalloid.
Nathan Goodyear

Thyroid hormones in fibrocystic breast dise... [Eur J Endocrinol. 1995] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...7788004

estrogen estradiol thyroid free T3 breast cyst cystic disease fibrocystic cancer

shared by Nathan Goodyear on 16 Nov 11 - No Cached
  • Nathan Goodyear on 16 Nov 11
     
    free T3 levels found to be higher in breast cyst fluid than in serum. This correlated with elevated K+/Na+ ratio which is associated with malignant transformation.  This elevated free breast cyst fluid correlated with estradiol concentration
Nathan Goodyear

Exercise-associated hyponatremia. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19523574

exercise induced hyponatremia hyponatremia endurance athletes endurance sports endurance athletes

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    hyponatremia due to exercise, or exercise induced hyponatremia, is multifactorial: over-hydration, poor renal clearance, SIADH thus inhibition of renal fluid clearance, and excessive Na loss through sweat.
Nathan Goodyear

Diagnosis and prevention of hyponatremia at an ultradistance triath... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10695851

hyponatremia triathlon endurance athletes endurance exercise endurance athletes weight

shared by Nathan Goodyear on 27 Jan 15 - No Cached
  • Nathan Goodyear on 27 Jan 15
     
    over hydration increases risk of hyponatremia.  Body weight is inversely associated with Na levels.  Weight evaluations are an appropriate means to evaluate.  Endurance triathlon athletes can lose up to 5% without any negative physiologic impact.
ashleyobama

Nembutal Liquid | pills nembutal |Nembutal Liquid | - 0 views

www.roidsmeds.com/...nembutal-liquid

shared by ashleyobama on 28 May 20 - No Cached
  • ashleyobama on 28 May 20
     
    Nembutal Liquid is best quality and prices at First Trust Chemicals. Visit our website and place your order online. Nembutal Liquid Pentobarbital (trade name: Nembutal) is a drug from the barbiturate class. It was widely used during the 1940s and 1950s as a sleeping pill (i.e. hypnotic) or anti-anxiety drug (i.e. sedative). Unlike modern sleeping pills, Nembutal is highly lethal in overdose. Because it is very reliable and brings about peaceful death, it is one of drugs of choice for assisted suicide. Nembutal is used by euthanasia organizations in the United States (Oregon Death With Dignity Act), Switzerland (Dignitas) and The Netherlands. Nembutal Liquid Since it was so easy to overdose on Nembutal (whether accidentally or intentionally), it was almost universally taken off the market and replaced by safer sleeping pills. Nembutal was removed from the Australian prescribing schedule in 1998. However, Nembutal remains in use by veterinary surgeons in order to euthanase bigger animals. Many people were successful in obtaining veterinary Nembutal for their suicide. The famous American actress Marilyn Monroe supposedly used Nembutal to end her life. The brand name "Nembutal" was coined by Dr. John S. Lundy, who started using it in 1930, from the structural formula of the sodium salt-Na (sodium) + ethyl + methyl + butyl + al (common suffix for barbiturates). Nembutal is trademarked and manufactured by the Danish pharmaceutical company Lundbeck
giselabreu

Homeopatia - 0 views

www.pharmalisboa.pt/...homeopatia

homeopathy medicine health

shared by giselabreu on 28 Feb 14 - No Cached
  • giselabreu on 28 Feb 14
     
    A Homeopatia é um método terapêutico baseado na prescrição de medicamentos produzidos a partir de substâncias extraídas da natureza e que podem ser de origem vegetal, mineral e animal. Cerca de 3.000 substâncias denominadas cepas, são a base dos medicamentos homeopáticos.
Nathan Goodyear

Neonatal abstinence syndrome and associated health care... [JAMA. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22546608

opioid opiates infants neonatal abstinence syndrome NAS pregnancy

shared by Nathan Goodyear on 14 Apr 14 - No Cached
  • Nathan Goodyear on 14 Apr 14
     
    Very disturbing trend.  Study finds that opioid addicted infants are on a dramatic risk in the US.  This study looked at Neionatal abstinence syndrome from 2000 to 2009.  This follows the significant increase in maternal opioid prescription use.  We physicians must do better.  Patients must demand better.  This study just focused on hospital costs directly associated with the Neonatal period.  No cost estimates are evaluated for long-term care.
Nathan Goodyear

Serum thymidine kinase 1 correlates to clinical stages and clinical reactions and monit... - 0 views

c.na2.content.force.com/...ervlet.EmailAttachmentDownload

thymidine kinase 1 TK-1 cancer

shared by Nathan Goodyear on 26 Jan 15 - No Cached
  • Nathan Goodyear on 26 Jan 15
     
    TK-1 to screen for cancer, as well as to follow therapy and recurrence.
Nathan Goodyear

https://www.cayugamed.org/docs/Nutrition_Update_for_the_Ultraendurance_Athlete%208.pdf - 0 views

www.cayugamed.org/...Ultraendurance_Athlete%208.pdf

endurance athletes endurance exercise nutrition athletes athlete

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    Nutrition for ultra endurance.  To be read.
golibeetscardio

Goli Nutrition Beets Cardio Gummies- Goli Beets Cardio Gummies, Reviews! - 1 views

https://goli-beets-cardio-gummies.company.site/ Goli Nutrition Beets Cardio Gummies Goli Beets Cardio Gummies Goli Beets Cardio Gummies Reviews ➢Direct purchase ➠Click here ➢ Product name ➠Go...

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