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Nathan Goodyear

Recovery after an Ironman triathlon: sustained inflammatory respons... - PubMed - NCBI - 0 views

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    Recovery period of Ironman triathlon associated with significantly increased inflammatory response.  The vast majority is resolved by day 5 in this study, though low-grade inflammation persisted beyond day 5.  Cortisol was significantly elevated and Testosterone was significantly decreased in the early recovery period.  Muscle damage and significant inflammation is a prominent finding in the recovery phase of a triathlon.
Nathan Goodyear

Fluid Balance During and After an Ironman Triathlon - ResearchGate - 0 views

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    ultra distance triathlon athletes lost 2.5 kg weight during event.  Athletes that developed hyponatremia appeared to be fluid overloaded during event.
Nathan Goodyear

The endurance triathlon: metabolic changes after each event and dur... - PubMed - NCBI - 0 views

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    Serum lactate elevates early in triathlon.  The greatest increase is associated with the swim event.  Muscle damage progressed through the 3 events (creatine phosphokinase and LDH).  Uric acid levels increased.  Recovery was seen out to 6 days post event.
Nathan Goodyear

Diagnosis and prevention of hyponatremia at an ultradistance triath... - PubMed - NCBI - 0 views

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    over hydration increases risk of hyponatremia.  Body weight is inversely associated with Na levels.  Weight evaluations are an appropriate means to evaluate.  Endurance triathlon athletes can lose up to 5% without any negative physiologic impact.
Nathan Goodyear

No indications of persistent oxidative stress in response to an iro... - PubMed - NCBI - 0 views

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    Oxidative stress markers remain elevated up to 5 days post ironman triathlon.
Nathan Goodyear

Exercise-induced right ventricular dysfunction and structural remodelling in endurance ... - 0 views

  • In a cohort of well-trained athletes, we demonstrated that intense endurance exercise causes an acute reduction in RV function that increases with race duration and correlates with increases in biomarkers of myocardial injury
  • no relationship between LV function and biomarker levels
  • focal gadolinium enhancement and increased RV remodelling were more prevalent in those athletes with a longer history of competitive sport, suggesting that repetitive ultra-endurance exercise may lead to more extensive RV change and possible myocardial fibrosis
  • ...22 more annotations...
  • he cardiac impact of both acute and cumulative exercise is greatest on the RV.
  • Greater reductions in RV function occurred in those athletes competing for a longer duration, suggesting that the heart has a finite capacity to maintain the increased work demands of exercise
  • cardiac injury is greatest in the least trained
  • Previous investigators have documented reductions in RV function in less trained subjects over the marathon distance
  • We enrolled elite and subelite athletes and found a significant association between fitness (VO2max) and the reduction in post-race RVEF
  • Even after many years of detraining, cardiac dilation may not completely regress in elite athletes
  • The focus on well-trained athletes may be of particular relevance, given that they perform exercise of highest intensity and duration most frequently, and, thus, may be at a greater risk of cumulative injury.
  • The lack of correlation between increases in troponin and changes in LV function seen in this study has been previously interpreted as evidence that post-exercise elevations in cardiac biomarkers are benign.
  • a significant correlation between changes in RVEF and post-race biomarker levels and this relationship was even stronger in the athletes who completed the race of longest duration, the ultra-triathlon
  • The correlations with RVEF, but not LVEF, provide further evidence of the differential effects of intense exercise on RV and LV function
  • BNP release during intense exercise is associated with greater relative increases in RV systolic pressures, but not LV pressures
  • BNP may provide a measure of both acute RV load and the resultant fatigue which occurs when this load is sustained
  • It has been demonstrated that ventricular load increases with exercise intensity and is greater for the RV than the LV,29 thus potentially explaining why the RV is more susceptible to fatigue after prolonged exercise.
  • This study demonstrates, for the first time, an association between endurance exercise of increasing duration and structural, functional, and biochemical markers of cardiac dysfunction in highly trained athletes
  • Functional abnormalities were confined to the RV and were largely reversible 1 week following the event
  • there remained a significant minority of athletes in whom there was evidence of myocardial fibrosis in the interventricular septum
  • RV abnormalities may be acquired through cumulative bouts of intense exercise and provides direction for prospective investigations aimed at elucidating whether extreme exercise may promote arrhythmias in some athletes.
  • the acute injury and chronic remodelling of the myocardium both disproportionately affect the RV and it remains possible that the two are linked.
  • focal DGE was confined to the interventricular septum and commonly at the site of RV attachment
  • emerging evidence that intense endurance exercise may be associated with an excess in arrhythmic disorders, the mechanisms for which remain unexplained
  • RVEF (and not LVEF) was reduced in athletes with complex ventricular arrhythmias when compared with healthy athletes and non-athletes without arrhythmias
  • it is premature to conclude that these changes may represent a proarrhythmic substrate
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    Study finds endurance racing results in reduce Right ventricle ejection fraction even in elite athletes.  This post-race RVEF reduction is associated with VO2max.
Nathan Goodyear

http://www.msma.org/docs/communications/momed/Excessive_Endurance_Exercise_and_Heart_Di... - 0 views

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    great review of data on cardiac damage associated with extreme endurance training.  These EEEs, that they are called, are rare in those < 40 and usually involved genetic defects.  This article points to aggressive preventive testing in those > 50.
Nathan Goodyear

Weight changes, sodium levels, and performance in the South African... - PubMed - NCBI - 0 views

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    Body weight post race was inversely associated with serum sodium i.e.  less weight loss was associated with lower serum sodium.  Body weight loss was unrelated to marathon time.
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