Group items tagged

Editorial from Dr. Moncrieff.  The title of the editorial tells you everything you need to know.  

Nice editorial response to "does testosterone treatment reduce mortality in men?"  This response points out the flaws with the study.   The point to be taken with all studies, is there will never be a study to end all studies that provides unequivocal results.  We as scientists must view the risks/benefits of all therapies from within the prism that is each person sitting in front of us.  First, and foremost, do no harm.

editorial discussion of the benefit of vitamin D in mitochondrial function.   Those in the vitamin D repletion arm of the study had a quicker recovery time to restored phospho-creatinine levels.  The quicker the recovery of phospho-creatinine levels, the shorter recovery phase and the likely improvement in athletic performance.

Running beyond 25 miles weekly is damaging to the heart according to this editorial.  

Editorial discussing the benefit of Metformin in prostate cancer.  The effect is through the inhbition of gluconeogenesis.  However, one wonders if a ketogenic diet with restriction of l-Glutamine would have the same effect without the potential side effects of Metformin?  The answer is logically yes.  

Great editorial on the complex metabolism of the cortisol:cortisone shunt.

high aromatase activity and conversion of testosterone to estrogen conversion plays a role in lupus and RA.  Inflammatory cytokines are shown to increase aromatase activity.

Growth hormone deficiency is safe and effective in those adults with GHD.

Influenza and other virus' induce cytokine production i.e. cytokine storm via TLR