Skip to main content

Home/ Dr. Goodyear/ Group items tagged MET

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
Nathan Goodyear

Chronic Inflammation in Obesity and the Metabolic Syndrome - 0 views

www.hindawi.com/...289645

inflammation obesity metabolic syndrome metabolic syndrome

shared by Nathan Goodyear on 12 Sep 14 - No Cached
  • Nathan Goodyear on 12 Sep 14
     
    Nice review/summary of inflammation and the systemic dysfunction that results leading to MetS.
Nathan Goodyear

Associations between Circulating Reproductive Hormones and SHBG and Prevalent and Incid... - 1 views

press.endocrine.org/...jc.2014-2464

metabolic syndrome metabolic syndrome men male hormone hormones health Testosterone DHT SHBG cFT free Testosterone

shared by Nathan Goodyear on 06 Oct 14 - No Cached
  • Nathan Goodyear on 06 Oct 14
     
    The best marker associated with MetS in older men was low SHBG. Low T, DHT, and cFT were found to be more biomarkers of poor health rather than causal.
Nathan Goodyear

Fifty- two-Week Treatment With Diet and Exercise Plus Transdermal Testosterone Reverses... - 0 views

onlinelibrary.wiley.com/...full

diet exercise nutrition diabetes metabolic syndrome men male hormone hormones low T low Testosterone

shared by Nathan Goodyear on 04 Mar 15 - No Cached
  • there appears to be a positive correlation between serum testosterone levels and insulin sensitivity in men across the full spectrum of glucose tolerance (Pitteloud et al, 2005), and this relationship is at least partially direct and not fully dependent on (changes in) elements of the MetS
  • supervised D&E alone led to significant improvements in testosterone concentrations, glycemic control, and components of the MetS
  • diet control, exercise, and testosterone supplementation may be beneficial in the management of men with T2D
  • ...7 more annotations...
  • androgen-deprivation therapy in males with prostatic cancer may be associated with an increased risk for T2D, which may be caused by negative effects on insulin sensitivity
  • insulin sensitivity, measured by HOMA, improved in both groups and with a significantly greater degree when testosterone was added to supervised D&E
  • Fasting insulin concentrations, a good representative of insulin sensitivity, did show a significant correlation with changes in circulating androgen levels, an observation in support of Pitteloud et al (2005), who showed a direct relationship between insulin sensitivity and circulating testosterone concentrations using the hyper-insulinemic euglycemic clamp technique
  • 52 weeks of testosterone treatment also significantly improved circulation levels of adiponectin and hsCRP, key serum markers of insulin sensitivity and hepatic steatosis
  • The changes in both adiponectin and hsCRP were significantly correlated with the therapy-induced changes in bioavailable testosterone
  • a negative correlation was found between hsCRP levels and bioavailable testosterone
  • serum PSA concentrations did not differ between the 2 treatment groups, indicating that short-term testosterone administration appears to be acceptably safe
  • Nathan Goodyear on 04 Mar 15
     
    Study of men with metabolic syndrome and type II Diabetes finds that diet and exercise alone improved glucose control and metabolic syndrome components by 31%.  The addition of Testosterone therapy increased this % to 81%.
Nathan Goodyear

PLOS ONE: Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men:... - 0 views

journals.plos.org/...article

Testosterone metabolic syndrome total Testosterone free Testosterone SHBG men male hormone hormones

shared by Nathan Goodyear on 03 Mar 15 - No Cached
  • Nathan Goodyear on 03 Mar 15
     
    Meta-analysis finds that men with low total Testosterone, free Testosterone, and SHBG are more at risk for MetS than those with elevated levels.
Nathan Goodyear

PLOS ONE: Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men:... - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0100409

metabolic syndrome Total Testosterone Total Testosterone free free Testosterone SHBG BMI obese overweight men male hormone hormones

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    Association of low TT, SHBG, and free Testosterone with MetS was found in this study on men.  The association was influenced by BMI i.e. the overweight were found to have a higher association than the normal BMI.
Nathan Goodyear

BMC Endocrine Disorders | Full text | The prevalence of metabolic syndrome and metaboli... - 0 views

www.biomedcentral.com/...9

metabolic syndrome metabolic syndrome obesity health europe Europeans

shared by Nathan Goodyear on 02 Aug 14 - No Cached
  • Nathan Goodyear on 02 Aug 14
     
    metabolic syndrome incidence in Europe far below that of the US.  One of the primary driving forces of MetS is obesity.
Nathan Goodyear

The role of testosterone in the m... [J Steroid Biochem Mol Biol. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19444934

low T Testosterone low T low Testosterone lipids glucose diabetes metabolic syndrome SHBG metabolic syndrome IR insulin resistance

shared by Nathan Goodyear on 14 Aug 14 - No Cached
  • Nathan Goodyear on 14 Aug 14
     
    Testosterone plays an important role in glucose and lipid metabolism.  Thus, low Testosterone, will result in increased disruption in the homeostasis of glucose and lipids resulting in increased weight, insulin resistance, diabetes, metabolic syndrome... Low SHBG was also shown to be associated with MetS
Richard Joseph

Sunglasses & Sunwear in Wentzville | St.Peters - 0 views

www.mobypicture.com/...17768077

sunwear in O'Fallon Optometrist in O'Fallon sunwear in Wentzville Optometrist in Wentzville Optometrist in St. peters sunwear in Bridgeton Optometrist in Bridgeton sunglasses in St. Louis

shared by Richard Joseph on 31 Jan 15 - No Cached
  • Richard Joseph on 31 Jan 15
     
    You simply come in for a routine eye exam or you are seeking treatment for an eye disease or condition, we are here to serve you. We happily accept vision insurance and work hard to make sure your eye care needs can be met within your budget.
Nathan Goodyear

Cyclooxygenase-2 Induces EP1- and HER-2/Neu-Dependent Vascular Endothelial Growth Facto... - 0 views

cancerres.aacrjournals.org/...554

COX-2 cancer HER-2 Celebrex VEGF metastasis prostate cancer lung cancer colorectal cancer

shared by Nathan Goodyear on 07 Aug 18 - No Cached
  • Nathan Goodyear on 07 Aug 18
     
    COX-2 is overexpressed in a variety of human cancers i.e. colorectal, prostate, lung adenocarcinoma.  This study hightlights the increased tumor metastatic potential via upregulation of VEGF-C via EP1 and HER-2 dependent pathways.  This upregulation was correlated with survival and mets.
Nathan Goodyear

Hypercalcemia: A Complication of Advanced Chronic Liver Disease | JAMA Internal Medicin... - 0 views

jamanetwork.com/...607804

liver hypercalcemia liver disease

shared by Nathan Goodyear on 21 Aug 18 - No Cached
  • Nathan Goodyear on 21 Aug 18
     
    Hypercalcemia is a common finding in liver disease, especially cancer of the liver, whether primary or mets.  Also, consider hyperparathyroidism and excessive vitamin D supplementation.
Nathan Goodyear

Interpreting raised serum ferritin levels | The BMJ - 1 views

www.bmj.com/...bmj.h3692

ferritin liver cancer inflammation liver disease renal failure metabolic syndrome

shared by Nathan Goodyear on 23 Aug 18 - No Cached
  • Nathan Goodyear on 23 Aug 18
     
    good read, though only abstract available here.  Elevated Ferritin is usually caused by inflammation, chronic alcohol use, liver disease, renal failure, MetS, or cancer.
Nathan Goodyear

Low serum albumin levels and liver metastasis are powerful prognostic markers for survi... - 0 views

onlinelibrary.wiley.com/...cncr.22300

albumin cancer liver metastasis

shared by Nathan Goodyear on 09 Jul 18 - No Cached
  • poor PS,8-10 the presence of liver metastases,7, 9, 10 and elevated LDH levels10 were independent prognostic factors
  • lymphopenia (HR of, 1.89; P = .04) and hypoalbuminemia (HR of 2.7; P < .0001) were independent prognostic factors for overall survival
  • lymphopenia in cancer patients remain unclear and may reflect in part poor nutrition
  • ...2 more annotations...
  • may result in part from the destruction of lymphocytes by the tumor and/or an impaired differentiation of lymphocytes progenitors
  • presence of liver metastasis (HR of, 2.27; P = .0003) and hypoalbuminemia were the 2 most powerful adverse prognostic factors
  • Nathan Goodyear on 09 Jul 18
     
    study finds that lympohopenia and low albumin was associated with the worse prognosis in 317 patients with liver mets with unknown primary cancer. 
Nathan Goodyear

High expression of Toll-like receptor 4/myeloid differentiation factor 88 signals corre... - 0 views

www.ncbi.nlm.nih.gov/...PMC2833250

colon cancer colorectal cancer cancer LPS lipopolysaccharides

shared by Nathan Goodyear on 11 Sep 17 - No Cached
  • Nathan Goodyear on 11 Sep 17
     
    High TLR4 and MyD88 expression on the surface of colorectal cancer cells associated with increase liver mets potential and worsened prognosis.  LPS works through TLR4 and MyD88.
Nathan Goodyear

Lipopolysaccharide-induced toll-like receptor 4 signaling enhances the migratory abilit... - 0 views

www.sciencedirect.com/...S0039606013001050

LPS lipopolysaccharides cancer

shared by Nathan Goodyear on 11 Sep 17 - No Cached
  • Nathan Goodyear on 11 Sep 17
     
    LPS stimulation induced increased mets potential in esophageal cell culture study.
Nathan Goodyear

Thus, these opinions are not based on all the relevant research that is available and a... - 0 views

Thus, these opinions are not based on all the relevant research that is available and are, therefore incomplete and biased

CD57 cancer metastasis NK cells NK immune system immunotherapy

shared by Nathan Goodyear on 05 Feb 19 - No Cached
  • Nathan Goodyear on 05 Feb 19
     
    CD 57 cells infiltrating solid tumor microenvironment yields positive prognosis. Inverse relationship for Mets.
Nathan Goodyear

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling | O... - 0 views

ocg.cancer.gov/...ately-activates-mapk-and-met-0

PAK1 oncogene oncogenes cancer

shared by Nathan Goodyear on 21 Mar 18 - No Cached
  • Nathan Goodyear on 21 Mar 18
     
    PAK1 is an oncogene. Here that is linked to genesis of breast cancer through the RAS-RAF-MEK-ERK-MAPK pathway. Ivermectin, a common anti-parasitic, is know to block this oncogene activity.
Nathan Goodyear

Importance of serum prolactin determinations in metastatic breast cancer patients | Ham... - 0 views

www.academia.edu/...astatic_breast_cancer_patients

cancer breast cancer liver prolactin

shared by Nathan Goodyear on 11 May 18 - No Cached
  • Nathan Goodyear on 11 May 18
     
    Prolactin is a useful marker for prognosis and metastatic potential for women with breast cancer and liver mets risk.
Nathan Goodyear

http://cancerres.aacrjournals.org/content/canres/62/6/1588.full.pdf - 0 views

cancerres.aacrjournals.org/...1588.full.pdf

doxycycline cancer

shared by Nathan Goodyear on 07 Jun 18 - No Cached
  • Nathan Goodyear on 07 Jun 18
     
    doxycycline to treat bone mets.
Nathan Goodyear

Hyperuricemia at The Time Of Diagnosis is a Factor for Poor Prognosis in Patients With ... - 0 views

www.ncbi.nlm.nih.gov/...PMC5454747

colorectal cancer uric acid

shared by Nathan Goodyear on 29 Aug 19 - No Cached
  • Nathan Goodyear on 29 Aug 19
     
    Small cross-sectional study finds that increased uric acid is associated with early Mets and poor prognosis.
Nathan Goodyear

Chemotherapeutic potential of curcumin for colorectal cancer. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12171541

curcumin tumeric cancer

shared by Nathan Goodyear on 11 Sep 17 - No Cached
  • Nathan Goodyear on 11 Sep 17
     
    Only abstract available here.  Good discussion of the effects of curcumin: curcumin inhibits carcinogenesis, increases glutathione production, inhibits promotion and progression (mets) of cancer, induces cell apoptosis (cell death).
« First ‹ Previous 61 - 80 of 134 Next › Last »
Showing 20▼ items per page