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Nathan Goodyear

Measurement of steroid hormones in s... [Scand J Clin Lab Invest. 2013] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...24033227

saliva salivary hormone testing hormones measurement

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    Study deals with the storage temp of salivary hormone samples.
Nathan Goodyear

Long-term stability of salivary cort... [Scand J Clin Lab Invest. 2005] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16081365

saliva salivary hormone hormones

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    Salivary cortisol samples shown to be stable for long length of time.
Nathan Goodyear

The association between erectile dysfu... [Scand J Public Health. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25114066

ED erectile dysfunction free Testosterone Total Testosterone Testosterone men male hormone hormones depression

shared by Nathan Goodyear on 13 Aug 14 - No Cached
  • Nathan Goodyear on 13 Aug 14
     
    Finnish study found no association between free Testosterone and Total Testosterone, and ED.
Nathan Goodyear

Triiodothyronine and breast cancer. [World J Clin Oncol. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25114863

T3 thyroid triiodothyronine breast cancer E2

shared by Nathan Goodyear on 13 Aug 14 - No Cached
  • Nathan Goodyear on 13 Aug 14
     
    T3 may have effects similar to Estradiol in breast cell proliferation.  This may be, but what about the effects on increased metabolism and resultant fat loss which leads to reduce inflammation...I believe this is all about context of the environment in the individual and the importance of customizing therapy.
Nathan Goodyear

Effects of thyroid hormones on hu... [J Steroid Biochem Mol Biol. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18328691

triiodothyronine T3 thyroid hormone hormones breast cancer E2 Estradiol

shared by Nathan Goodyear on 13 Aug 14 - No Cached
  • Nathan Goodyear on 13 Aug 14
     
    T3 may promote cancer cell proliferation says study.  Triiodothyronine was found to enhance the MCF-7 and T47-D breast cancer cell lines.  The conclusion of the abstract discusses a role of T3 in breast cancer development and progression.  This likely has more to do with progression than development through increased metabolism of the cell lines.
Nathan Goodyear

Androgen deficiency and mitochondrial dysfunction: implications for fatigue, muscle dys... - 0 views

www.degruyter.com/...hmbci.2011.132.xml

men male hormone hormones androgens low T low Testosterone low T Testosterone insulin resistance IR diabetes metabolic syndrome obesity mortality disease cardiovascular

shared by Nathan Goodyear on 12 Aug 14 - No Cached
  • Nathan Goodyear on 12 Aug 14
     
    low Androgens, or low T to be specific, associated with insulin resistance, diabetes, metabolic syndrome, obesity, and mortality.
Nathan Goodyear

Correlation between inflammatory markers a... [J Obstet Gynaecol. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25111421

TNF-alpha pregnancy IR insulin resistance GDM gestational diabetes hsCRP

shared by Nathan Goodyear on 13 Aug 14 - No Cached
  • Nathan Goodyear on 13 Aug 14
     
    Interesting, yet not surprising.  TNF-alpha has strong correlation with IR in pregnancy.  This follows metabolic endotoxemia pathophysiology.  I believe this could be used to assess risk for PIH...
Nathan Goodyear

The role of testosterone in the m... [J Steroid Biochem Mol Biol. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19444934

low T Testosterone low T low Testosterone lipids glucose diabetes metabolic syndrome SHBG metabolic syndrome IR insulin resistance

shared by Nathan Goodyear on 14 Aug 14 - No Cached
  • Nathan Goodyear on 14 Aug 14
     
    Testosterone plays an important role in glucose and lipid metabolism.  Thus, low Testosterone, will result in increased disruption in the homeostasis of glucose and lipids resulting in increased weight, insulin resistance, diabetes, metabolic syndrome... Low SHBG was also shown to be associated with MetS
Nathan Goodyear

Testosterone and benign prostatic hyperplasia Jarvis TR, Chughtai B, Kaplan SA, - Asian... - 0 views

www.ajandrology.com/preprintarticle.asp

Testosterone BPH low T low Testosterone prostate cancer men male hormone hormones

shared by Nathan Goodyear on 01 Dec 14 - No Cached
  • The prevalence of hypogonadism (often defined as serum testosterone < 300 ng dl−1 ) ranges from 6% [10] to as high as 38%
  • The process of BPH, however, continues as men age and despite the fact their serum testosterone decreases
  • Liu et al. [12] demonstrated that in a group of older males (mean age 59.8 years) that there was not a significant correlation of serum testosterone levels (total, free or bioavailable) with either prostate volume or International Prostate Symptom Score (IPSS)
  • ...11 more annotations...
  • in eugonadal men, studies have demonstrated that the prostate can increase in volume by approximately 12%
  • There seems to be little doubt that the treatment with testosterone of a young hypogonadal male leads to significant growth of the prostate
  • Behre et al. [22] demonstrated increased prostate volume and prostate-specific antigen (PSA) levels in hypogonadal men
  • Most studies, however, have shown no effect of exogenous androgens on PSA or prostate volume for older hypogonadal males
  • They argue that the prostate is relatively insensitive to changes in androgen concentration at normal levels or in mild hypogonadism because the AR is saturated by androgens and therefore maximal androgen-AR binding is achieved. Conversely, the prostate is very sensitive to changes in androgen levels when testosterone is low
  • saturation model
  • visceral obesity (one of the most significant components of metabolic syndrome) is associated with prostate volume and influences prostate growth during TRT.
  • This hypothesis of inflammation induced LUTS is also argued to be a mechanism for improvement of LUTS with PDE5I
  • The concept, therefore, that treatment with TRT of hypogonadal males with metabolic syndrome might lead to improvement/stabilization of their LUTS, appears to be confirmed in recent work by Francomano et al.
  • There was also an improvement in components of the patient's metabolic syndrome (such as BMI, waist circumference, hemoglobin A1c [HbA1c], insulin sensitivity, and lipid profile) as well as inflammatory markers and C-reactive protein.
  • They concluded that TRT was safe in this group of men, and hypothesize that TRT mitigates the pro-inflammatory factors associated with metabolic syndrome.
  • Nathan Goodyear on 01 Dec 14
     
    Authors review the literature behind Testosterone and BPH.  The authors highlight the 4 proposed theories behind BPH: Testosterone, Estrogen, inflammation, and metabolic.   The conclusion is mixed: pointing out that no high level of evidence exists on either side of the debate of Testosterone and BPH.
Nathan Goodyear

Testosterone and metabolic syndrome Cunningham GR, - Asian J Androl - 0 views

www.ajandrology.com/preprintarticle.asp

Testosterone metabolic syndrome

shared by Nathan Goodyear on 16 Feb 15 - No Cached
  • Nathan Goodyear on 16 Feb 15
     
    to be read
Nathan Goodyear

Testosterone therapy in men with prostate cancer: literature review, clinical experienc... - 0 views

www.ajandrology.com/preprintarticle.asp

Testosterone prostate cancer cancer prostate

shared by Nathan Goodyear on 16 Feb 15 - No Cached
  • Nathan Goodyear on 16 Feb 15
     
    To be read
Nathan Goodyear

Controversies in testosterone replacement therapy: testosterone and cardiovascular dise... - 0 views

www.ajandrology.com/preprintarticle.asp

Testosterone CVD cardiovascular disease

shared by Nathan Goodyear on 16 Feb 15 - No Cached
  • Nathan Goodyear on 16 Feb 15
     
    to be read.
Nathan Goodyear

Oestrogen receptor-β expression in melanocytic lesions - Schmidt - 2006 - Exp... - 0 views

onlinelibrary.wiley.com/...8D4792ABFD8FD5B93759596.f01t01

melanoma cancer skin ER alpha ER-alpha ER beta ER-beta ER estrogen receptor

shared by Nathan Goodyear on 21 Oct 14 - No Cached
  • Nathan Goodyear on 21 Oct 14
     
    ERbeta found to be associated with benign nevi and malignant melanomas.  No association was found with ERalpha.
Nathan Goodyear

Exercise and circulating cortisol levels... [J Endocrinol Invest. 2008] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...18787373

Cortisol exercise hormone hormones ACTH high intensity training low intensity testing

shared by Nathan Goodyear on 03 Aug 14 - No Cached
  • Nathan Goodyear on 03 Aug 14
     
    Study finds moderate and high intensity exercise associated with an elevated ACTH and serum Cortisol.
Nathan Goodyear

Dichloracetate and cancer: a new paradigm for an old drug. - 0 views

doi.org/...j.bbcan.2014.08.005

DCA dichloroacetate dichloracetic acid cancer

shared by Nathan Goodyear on 16 Nov 18 - No Cached
  • Nathan Goodyear on 16 Nov 18
     
    DCA in the treatment of cancer.
Nathan Goodyear

Mistletoe viscotoxins increase natural killer cell‐mediated cytotoxicity - Ta... - 0 views

febs.onlinelibrary.wiley.com/...j.1432-1033.2002.02932.x

cancer mistletoe NK NK cells

shared by Nathan Goodyear on 08 Jul 18 - No Cached
  • Nathan Goodyear on 08 Jul 18
     
    Study finds that mistletoe augments NK activity not via an increase in NK numbers.
Nathan Goodyear

The effectiveness of vitamin C i... [J Manipulative Physiol Ther. 1999] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...10543583

vitamin C flu influenza

shared by Nathan Goodyear on 02 Oct 11 - No Cached
  • Nathan Goodyear on 02 Oct 11
     
    High dose vitamin C therapy reduces symptoms by 85%
Nathan Goodyear

BPS Publications - 0 views

bpspubs.onlinelibrary.wiley.com/...j.1476-5381.2012.02027.x

CBD prostate cancer

shared by Nathan Goodyear on 13 Feb 19 - No Cached
  • Nathan Goodyear on 13 Feb 19
     
    CBD and prostate cancer
Nathan Goodyear

Non-toxic potentiation of cancer chemotherapy b... [Int J Cancer. 1987] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...3666992

IV vitamin C IV vitamin K3 vitamin C K K3 chemotherapy vitamin C vitamin K3

shared by Nathan Goodyear on 16 Oct 13 - No Cached
  • Nathan Goodyear on 16 Oct 13
     
    IV vitamin C and K3 induces cancer cell death through production of H2O2 in catalase deficient cancer cells.  Pretreament shown to potentiate traditional chemotherapy.
Nathan Goodyear

DISTRIBUTION OF ASCORBIC ACID, METABOLITES AND ANALOGUES IN MAN AND ANIMALS - Hornig - ... - 0 views

onlinelibrary.wiley.com/...full

vitamin C brain adrenals heart

shared by Nathan Goodyear on 28 Feb 18 - No Cached
  • Nathan Goodyear on 28 Feb 18
     
    The tissues that have the highest concentrations of vitamin C are adrenal, pituitary, brain, heart, pancrease, and kidneys.
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