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Matti Narkia

Calorie intake linked to cell lifespan, cancer development - 0 views

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    "ScienceDaily (Dec. 17, 2009) - Researchers from the University of Alabama at Birmingham (UAB) have discovered that restricting consumption of glucose, the most common dietary sugar, can extend the life of healthy human-lung cells and speed the death of precancerous human-lung cells, reducing cancer's spread and growth rate. The research has wide-ranging potential in age-related science, including ways in which calorie-intake restriction can benefit longevity and help prevent diseases like cancer that have been linked to aging, said principal investigator Trygve Tollefsbol, Ph.D., D.O., a professor in the Department of Biology. "These results further verify the potential health benefits of controlling calorie intake." Tollefsbol said. "Our research indicates that calorie reduction extends the lifespan of healthy human cells and aids the body's natural ability to kill off cancer-forming cells.""
Matti Narkia

Anticancer Properties of Ganoderma Lucidum Methanol Extracts In Vitro and In Vivo - Nutrition and Cancer - 0 views

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    Anticancer properties of Ganoderma lucidum methanol extracts in vitro and in vivo. Harhaji Trajković LM, Mijatović SA, Maksimović-Ivanić DD, Stojanović ID, Momcilović MB, Tufegdzić SJ, Maksimović VM, Marjanović ZS, Stosić-Grujicić SD. Nutr Cancer. 2009;61(5):696-707. PMID: 19838944 DOI: 10.1080/01635580902898743 Anticancer activities of various extracts of the medicinal mushroom, Ganoderma lucidum, have been widely demonstrated and are mainly associated with the presence of different bioactive polysaccharides and triterpenoids. We have evaluated and compared in vitro and in vivo the antitumor effects of two preparations from Ganoderma lucidum: a methanol extract containing total terpenoids (GLme) and a purified methanol extract containing mainly acidic terpenoids (GLpme). Both extracts inhibited tumor growth of B16 mouse melanoma cells inoculated subcutaneously into syngeneic C57BL/6 mice and reduced viability of B16 cells in vitro, whereby GLme exhibited stronger effect. Furthermore, anticancer activity of GLme was demonstrated for the first time against two other rodent tumor cell lines, L929-mouse fibrosarcoma and C6-rat astrocytoma. The mechanism of antitumor activity of GLme comprised inhibition of cell proliferation and induction of caspase-dependent apoptotic cell death mediated by upregulated p53 and inhibited Bcl-2 expression. Moreover, the antitumor effect of the GLme was associated with intensified production of reactive oxygen species, whereas their neutralization by the antioxidant, N-acetyl cysteine, resulted in partial recovery of cell viability. Thus, our results suggest that GLme might be a good candidate for treatment of diverse forms of cancers.
Matti Narkia

Uffe Ravnskov - Wikipedia, the free encyclopedia - 0 views

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    "Uffe Ravnskov (born 1934) is a Danish independent researcher, a member of various international scientific organisations, and a former private medical practitioner in Sweden. In recent years he has gained international recognition for his research into numerous scientific studies, leading to the publication of a book which stated that the widely popularised Lipid Hypothesis is scientifically invalid."
Matti Narkia

Hyperlipid: Physiological insulin resistance and palmitic acid again - 0 views

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    "I like palmitic acid. It causes insulin resistance. Thank goodness. Ted sent me this link. It's depressing. I'm going to discuss a thought drug. I'm going to call it Palmitofake, and it can be developed by Pfizer, no, Fort Dodge. I particularly dislike FD for anaesthesia related reasons. So what does Palmitofake do? BTW, if you didn't need any other hint you can tell this drug is going to bomb as there is neither an x, y or z in its name. Trust FD to screw up (in my mind). Palmitofake is a fluoride substituted analogue of palmitic acid which irreversibly binds to the acyl-CoA interaction site of JNK1 and so inhibits the pathway by which palmitic acid keeps GLUT4 transporters off of the cell surface membrane, whole body-wide. The logic to this is that the lipotoxin, palmitic acid (nature's second biggest mistake, the biggest was obviously cholesterol) can no longer keep glucose out of cells and metabolism can run, unimpaired by fat, for ever on glucose. Woo hoo bring on the glucose."
Matti Narkia

n-3 Fatty acids and cardiovascular disease evidence explained and mechanisms explored. - Clinical Science (2004) 107, 1-11 - P.C. Calder - 0 views

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    n-3 Fatty acids and cardiovascular disease: evidence explained and mechanisms explored. Calder PC. Clin Sci (Lond). 2004 Jul;107(1):1-11. Review. PMID: 15132735 DIETARY RECOMMENDATIONS FOR INTAKE OF LONG-CHAIN n-3 PUFAS It is clear from the forgoing discussion that long-chain n-3 fatty acids have been proven to be effective in secondary prevention of MI, with a particularly marked effect on sudden death. Thus it would be prudent to advise post-MI patients to increase long-chain n-3 PUFA consumption. Epidemiological studies, studies investigating effects on classic and emerging risk factors and mechanistic studies indicate that long-chain n-3 fatty acids also play a key role in primary prevention. This is supported by studies in animal models, including monkeys. Thus long-chain n-3 fatty acid consumption should be promoted for all individuals especially those at risk of developing cardiovascular disease. This is the reason why a number of organizations have now made recommendations relating to the intake of fatty fish (for example [3]) and of long-chain n-3 PUFAs (Table 6). It is clear that there is a wide gap between current intakes of long-chain n-3 PUFAs and many of these recommendations (Table 6). To meet these recommendations strategies other than increased consumption of fatty fish may be required.
Matti Narkia

ERA JUMP: Omega-3 fatty acids and plaque - The Heart Scan Blog - 0 views

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    "The results of the uniquely-constructed ERA JUMP Study were just released, a fascinating study of the relationship of omega-3 fatty acids to coronary and carotid plaque. The study adds insight into why the Japanese experience only one third of the heart attacks of Americans, and why Japan occupies the bottom of the list for least heart attacks among all developed countries. The Electron-Beam Tomography, Risk Factor Assessment Among Japanese and U.S. Men in the Post-World War II Birth Cohort Study (ERA JUMP), a collaborative U.S.-Japanese effort, compared three groups of men: -- 281 Japanese men living in Japan -- 306 non-Japanese men living in the U.S. (Pittsburgh, Pennsylvania) -- 303 Japanese Americans (having both parents Japanese without "ethnic admixture") living in Hawaii. The last group represents a group that is genetically similar to the group in Japan, but exposed to an American diet and lifestyle. Three main measures were compared: -- Blood levels of omega-3 fatty acids, EPA and DHA) -- Carotid intimal-medial thickness (CIMT, the thickness of the carotid artery lining that can serve as an index of body-wide atherosclerosis) -- Coronary calcium (heart scan) scores."
Matti Narkia

High doses of vitamin D could cut relapse rate among MS sufferers - Times Online - 0 views

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    "Powerful new evidence about the ability of vitamin D to stem a wide range of diseases has brought the prospect of a nationwide programme to prescribe it in Scotland as a dietary supplement significantly closer. Reports at the weekend suggested that experts were increasingly convinced that the so-called sunshine drug - whose significance was first revealed in detail by The Times last year - could make a difference to the country's appalling health record. New research suggests that high doses of vitamin D could dramatically cut the relapse rate in people with multiple sclerosis. According to scientists in Canada, more than a third of sufferers taking high levels of supplement
Matti Narkia

Mechanisms of Berberine (Natural Yellow 18)-Induced Mitochondrial Dysfunction: Interaction with the Adenine Nucleotide Translocator -- Pereira et al. 105 (2): 408 -- Toxicological Sciences - 0 views

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    Mechanisms of berberine (natural yellow 18)-induced mitochondrial dysfunction: interaction with the adenine nucleotide translocator. Pereira CV, Machado NG, Oliveira PJ. Toxicol Sci. 2008 Oct;105(2):408-17. Epub 2008 Jul 3. PMID: 18599498 doi: 10.1124/jpet.107.128017 The data from the present work appear to show that berberine also presents some degree of toxicity to "nontumor" systems, which should be carefully understood. ANT inhibition in nontumor cells by berberine would be responsible for a decrease in energy production and could also result in MPT induction. To the best of our knowledge, no full toxicity assessment exists for berberine in humans, although its use in several commercially available supplements suggests that the compound may present a relatively wide safety interval. In fact, a study with patients with congestive heart failure treated with 1.2 g/day of oral berberine revealed low toxicity and resulted into an average plasma concentration of 0.11 mg/l which would translate into 0.3µM (Zeng and Zeng, 1999Go). Repeated cumulative treatments, alternative forms of formulation (e.g., topical application vs. injection) or more importantly, active mitochondrial accumulation due to its positive charge would be expected to increase its concentration in cells into the range of concentrations used in this study. Empirical data from nontraditional medicines plus the use of extensive clinical assays would allow the use of berberine as a promising antimelanoma agent while maintaining its safety for humans. In radial/vertical forms of melanoma, a possible topical application of berberine would also be possible, thus minimizing side effects on other organs. In conclusion, the present work identifies the ANT as an important target for berberine, with clear relevance for its proposed antitumor effects.
Matti Narkia

Berberine - Wikipedia, the free encyclopedia - 0 views

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    "Berberine is a quaternary ammonium salt from the group of isoquinoline alkaloids. It is found in such plants as Berberis, goldenseal (Hydrastis canadensis), and Coptis chinensis, usually in the roots, rhizomes, stems, and bark. Berberine is strongly yellow colored, which is why in earlier times berberis species were used to dye wool, leather and wood. Wool is still today dyed with berberine in Northern India Berberine (BBR) is a natural compound with up-regulating activity on both low-density-lipoprotein receptor (LDLR) and insulin receptor (InsR). This one-drug-multiple-target characteristic might be suitable for the treatment of metabolic syndrome.[12] Berberine has been tested and used successfully in experimental[13] and human diabetes mellitus.[14][15][16] Berberine has been shown to lower elevated blood glucose as effectively as metformin.[17] The mechanisms include inhibition of aldose reductase,[18] inducing glycolysis,[19] preventing insulin resistance[20] through increasing insulin receptor expression[14] and acting like incretins. Berberine has drawn extensive attention towards its antineoplastic effects.[43][44] It seems to suppress the growth of a wide variety of tumor cells including breast cancer,[45] leukemia, melanoma,[46] epidermoid carcinoma, hepatoma, oral carcinoma, tongue carcinoma,[47] glioblastoma, prostate carcinoma, gastric carcinoma.[48][49] Animal studies have shown that berberine can suppress chemical-induced carcinogenesis, tumor promotion, tumor invasion,[50][51][52][53][54] prostate cancer,[55][56][57][58] neuroblastoma,[59][60] and leukemia.[34][61] It is a radiosensitzer of tumor cells but not of normal cells
Mango Dash india

Mango Dash: Beneficial Of Mango Juice During Pregnancy - 0 views

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    Mango is useful fruit for pregnant women as it contain good amount of iron that enables to maintain the HB level and proper oxygen flow. It is suggested that problems during menstruation. Mango relaxes the muscles and prevent abortion due to presence of calcium and magnesium.

    Beneficial in pregnancy of the Mango shakes are having important health benefits during pregnancy due to presence of iron both in milk and mango. Iron is an important mineral required during pregnancy.

    Mango is considered to have a rather beneficial effect on the baby's growth patterns. Mango juice for pregnancy is a delightful option. The fact that it has a low calorie count along with significant resources of vitamin C, fiber and vitamin A, it only serves to help increase the speed of the child's physical and mental development. Moreover, the beta carotene content within the fruit means that it significantly helps prevent the development of heart disease in both the mother as well as the child.

    A pregnant woman should eat at least one mango a day - the calcium and magnesium of the mango relaxes the muscles, relieves stress and prevents abortion.Mango is a tropical tree cultivated in many regions of India and now distributed wide across the world in many continents. Usually, fruits grow at the end of a long, string like stem, with sometimes more than one fruit to a stem.
Willow O'Donnell

Refurbished LifeCare Abbott Hospira Plum 5000 Infusion IV Pump - 0 views

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    Refurbished LifeCare Abbott Hospira Plum 5000 Infusion IV Pump is a single channel volumetric infusion pump with data port for external communications. It is a multi-line, general purpose infusion system designed to meet the need for hospital-wide device standardization. * Refurbished * 1-Year Warranty .
Mango Dash india

Alphonso Mango juice - 0 views

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    Mangoes have unlimited qualities which make them different from other seasonal fruits.Alphonso Mango juice is a seasonal fruit considered to be among the most superior varieties of the mango fruit in terms of sweetness, richness and flavour of mango juice.
    In this many variety of mangoes and mango juice is named after Alphonso Albuquerque,a nobleman and military expert who helped establish portuguese colonies in India. The Portuguese introduced grafting on mango trees to produce extraordinary varieties like Alphonso mango juice.The fruit alphonso mango was then introduced to the Konkan region in Maharashtra, Gujarat and parts of south India.
    Alphonso mango juice is also one of the most expensive varieties of mango and it is grown mainly in the western part of India including Sindhudurg, Ratnagiri and Raigad districts and in the Konkan region of India. Each mango weighs between 150 grammes and 300 grammes.

    Uses of alphonso mango is generally referred to as alphonso in Maharashtra and Gujarat, and alphonso mango juice is used to make sweets, candies and smoothies and mango drinks using Alphonso mango pulp.

    Alphonso Mango juice Products We offer wide variety of superior quality Alphonso Mango juice Products including mango juice pulp, mango slice, alphonso mango drink, fresh mango juice pulp and alphonso mango juice. The mango juice fruit pulp and juices are hygienically processed and packed. Natural taste of fruits are offered to clients across the market.
Mango Dash india

Mango Juice Tetra Pack - 0 views

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    Mango Juice In order to maintain our Best will among our valuable patrons, we are actively engaged in manufacturing, exporting and supplying superior quality of Mango Juice Tetra Pack. These Mango Juice tetra pack is highly demanded in the market due to its long lasting freshness, purity and unique flavor. A Mango Juice Tetra Pack skilled professionals processed this juice using the best quality of mango juice and other allied ingredients that are procured form the certified vendors of the industry. Additionally, it can be used for drinking purpose by our patrons in the summer season.
    Mango Juice are the foremost manufacturer, exporter and supplier of the superior quality of Litchi Juice Tetra Pack that is precisely processed using the quality assured Litchi juice and modern technology in compliance with the set industry guidelines. Our quality controllers check its quality against varied parameters before delivering it to our esteemed clients. Our offered Mango Juice tetra pack is highly demanded in the market due to its hygienically processed, freshness and long shelf life features. In addition to this, Everyone clients can use this tetra pack for the drinking purpose in the summer season.
    In Mango Drink order to meet the diverse requirements of our esteemed any clients, we are engaged in manufacturing and supplying an extensive range of Orange Juice Tetra Pack. The mango juice tetra pack offered by us is widely used in summer season for drinking in the any time. Our product offered tetra pack is precisely processed at our premises making use of the fine grade ingredients and Good processing techniques. High nutritious value, long shelf life and freshness are the features of this mango juice tetra pack. Additionally, it is available in the market at competitive prices.
Mango Dash india

Mango Dash: Mango Juice Pet Bottles Manufacturers - 0 views

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    Mango Juice are involved in the distribution, import and export of high-quality Mango Juice to our clients. Made using the best quality Mangoes, this juice is rich in nutritional content and contains no preservatives or added flavors. It is completely natural. Product specification With the help of our professionals, we have been engaged in manufacturing, exporting and supplying Mango Juice Pet Bottle. The offered juice is processed using fresh mangoes extracts to give a natural flavor. This juice is processed under the supervision of our experts under the utmost hygiene environment as per the food processing industry norms. We offer this healthy Mango Juice Pet Bottle in different capacity bottles as per the requirements of clients. Features: Rich taste Natural flavor Long shelf life Purity Mango Juice in Pet Bottles is a complete rejuvenator and helps in maintaining overall health by balancing digestive functions and cleansing the stomach. Our products are highly appreciated from various clients for accurate composition, purity and delightfully tasty. These fruits juice is very effective in case of heat strokes, which is extracted from fresh fruits, which is extremely durable. Clients can avail from us at affordable price. We supply Mango Juice in Pet Bottles which is very much nutritious, and rich in vitamins and other minerals. We manufacture these mango juices using quality mangoes nutritious as well extracted from latest technology. These mango juices offered by us natural Mango Drinks and do not contain any artificial ingredients. Our mango juice drink is refreshing, nutritious and is an abundant source of minerals and energy. Packaging Materials Packaging materials are considered to be an essential material for proper and safe delivery of goods. These are widely demanded for protecting perishable as well as non perishable goods. With the hep of these materials, different kind of commodities are packed like plastic containers,elec
Willow O'Donnell

Refurbished LifeCare Abbott Hospira Plum 5000 Infusion IV Pump - 0 views

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    Refurbished LifeCare Abbott Hospira Plum 5000 Infusion IV Pump is a single channel volumetric infusion pump with data port for external communications. It is a multi-line, general purpose infusion system designed to meet the need for hospital-wide device standardization.
Shelia Morales

Skincare & Skinmedica Laser Treatments St. louis | O'Fallon - 0 views

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    Cutera was founded in 1998 and has quickly become a leader in the laser and light-based aesthetic market. Their lasers are used widely by primary care physicians, dermatologists, plastic surgeons and gynecologists for safe, effective and non-invasive aesthetic treatments for their patients.
Mango Dash india

Mango Dash: Mango Juice Exporter and Manufacturer In India - 0 views

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    Exporter and Manufacturer In India, an online business directory offering a comprehensive database of companies engaged in export of Mango Juice. Buyers can browse the catalogs of these exporters of Mango Juice and send a request for product details. Mango Dash All our products are made with real fruit juice or pulp. Mango Pulp used for making the drinks is made from choicest mangoes brought from South India which is the World's largest producer of Mangoes. Our assortment of juicy mango and other drinks offer essential minerals, antioxidants, fiber and vitamin A and C, and is an excellent way of repletion of lost potassium. Our products are available in a wide range of flavours and pack sizes. Exporter and Manufacturer of packaged mango juice, fresh mango juices, mango juice, mango drinks, dash mango juice (1.ltr.) mango juice 180ml, mango New SKU 125 ml launched. Contact Details Vishal Beverages Private Limited 43-A, Industrial Estate, Laxmi Bai Nagar, Kila Maidan, Indore, Madhya Pradesh -452006, India Catalogs :http://mangodashindia.com/ Real Juices, Vyara Manufacturer of packaged fruit juices, mango juice, packaged fruit juices, apple juice, mango juice, grapes juice Contact Details Opp. Kbp Township Main Gate, Anumala Post, Dist. Tapi, Vyara, Gujarat -394651, India Yummy Juice, Bihar Manufacturer of packaging juice, mango, packaging juice, apple, mango Contact Details Station Road, Nagbadhia, Gaya, Near Dr. Qskhan, Bihar, Bihar -823001, India Sky Beverages [India] We are manufacturers of soft drink, mango juice, energy drinks, orange juice, jira masala drink, soda drink, mineral water etc. Business Type : Manufacturer / Exporters Address : Sky BeveragesrnPhase - 4, Plot - 1523,rnG.i.d.c , Wadhwancity. (Gujrat) India Parle Agro Pvt. Ltd., Mumbai Exporter and Manufacturer of mango juice, mango frooti, mango frooti, appy classic, appy fizz, confectionery, hard pepemint, hard cinnamon mint, packaged drinking water,
wsames34

Value Zinc: Three top Health benefits of Zinc for Pregnant women - 0 views

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    Most of the benefits associated with Zinc for women is tagged with its regular intake, to have the benefits mentioned below. 80% associated with girls world-wide are having the deficiency of Zinc. An everyday supplementing for ladies overall with 9. 6 mg
Willow O'Donnell

Abbott Hospira Plum 5000 Infusion IV Pump - 0 views

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    Refurbished LifeCare Abbott Hospira Plum 5000 Infusion IV Pump is a single channel volumetric infusion pump with data port for external communications. It is a multi-line, general purpose infusion system designed to meet the need for hospital-wide device standardization
Bodywise Services UK

Essential Vitamins and Minerals for the Immune System | Blog - Bodywiseuk - 0 views

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    The immune system requires a wide range of vitamins and minerals to function properly, but here we have listed the three of the most important ones - and these also tend to be ones that people struggle to get enough of from their diet!
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