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izzy kelly

Study finds brain connectivity, memory improves in older adults after walking -- Scienc... - 0 views

  • They become disconnected, and as a result, people lose their ability to think clearly and remember things. We're demonstrating that exercise training strengthens these connections."
  • walking may decrease cerebral blood flow and improve brain function in older adults with mild cognitive impairment.
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    correlation between exercise and memory. i'd be interested to see the long-term effects.
katherine-medina

Increased 3-O-sulfated heparan sulfate in Alzheimer's disease brain is associated with ... - 1 views

  • Genetic factors contribute substantially to the pathological process of AD as demonstrated by the fact that the genetic heritability in AD is in the range of between 60 and 80% (10).
  • however, whether the variants alter the level of 3-OST-1 enzyme activity to change the structure of HS remains unknown
    • katherine-medina
       
      Good to note what exactly the article remains unsure about
  • The synthesis of additional 13C-labeled calibrants to cover these three reported 3-O-sulfated tetrasaccharides will be the subject for future study.
    • katherine-medina
       
      LOOK INTO THIS PART CAYSE THEY ARE SAYING THAT THEY ARE NOT FULLY SURE
  • ...4 more annotations...
  • the elevation of total HS and the percentage of the 3-O-sulfated domain in HS.
  • HS and tau revealed that the sugar mainly interacts with the proline-rich region 2, a repeat domain 2 in tau protein
  • Further analysis of the distribution of 3-O-sulfated HS from different areas of AD brains will be of interest and the subject for a subsequent study.
  • Experimental design
    • katherine-medina
       
      READ THIS IF THIS TOPIC COMES BACK UP AGAIN
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    A interesting study about a sulfate that suggests that Alzheimer's is genetic
Sean Nash

Science Daily: News & Articles in Science, Health, Environment & Technology - 3 views

  • Your source for the latest research news
    • Sean Nash
       
      You'll want this resource...
Sean Nash

Race car drivers tend to blink at the same places in each lap - 4 views

  • The world goes dark for about one-fifth of a second every time you blink, a fraction of an instant that’s hardly noticeable to most people. But for a Formula One race car driver traveling up to 354 kilometers per hour, that one-fifth means almost 20 meters of lost vision
  • People are often thought to blink at random intervals, but researchers found that wasn’t the case for three Formula drivers.
  • the drivers tended to blink at the same parts of the course during each lap, cognitive neuroscientist Ryota Nishizono and colleagues report in the May 19 iScience
    • Sean Nash
       
      Interesting. So, do we do the same thing while driving around town? Could you design a method to record eye blinks as people drive known routes around town? We could simultaneously use the Arduino Science Journal app on the iPhone to also correlate physical data in a moving car like acceleration/deceleration, motion in X, Y, Z directions, etc. I wonder if we could find a correlation in everyday driving that could help from a safety perspective?
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  • He was surprised to find almost no literature on blinking behavior in active humans even though under extreme conditions like motor racing or cycling
    • Sean Nash
       
      OK, now this SCREAMS: "potential research idea."
  • Nishizono and colleagues mounted eye trackers on the helmets of three drivers and had them drive three Formula circuits
  • Where the drivers blinked was surprisingly predictable, the team found. The drivers had a shared pattern of blinking that had a strong connection with acceleration, such that drivers tended not to blink while changing speed or direction — like while on a curve in the track — but did blink while on relatively safer straightaways.
    • Sean Nash
       
      What sort of implications does this have for driving in key, known, busy interchanges in KC? Could we potentially provide data to show certain stretches of highway need more signage, etc? That could have civil engineering implications.
  • “We think of blinking as this nothing behavior,” he says, “but it’s not just wiping the eyes. Blinking is a part of our visual system.”
  • Nishizono next wants to explore what processes in the brain allow or inhibit blinking in a given moment, he says, and is also interested in how blinking behavior varies among the general population.
    • Sean Nash
       
      While the "brain" part might move beyond our feasibility, the potential of finding real correlations to driving patterns or routes is a completely different spin-off and one that could have really practical suggestive applications for city planners, etc.
katherine-medina

A virus of hyperthermophilic archaea with a unique architecture among DNA viruses | PNAS - 0 views

  • ssDNA, ssRNA, and ds
  • One of these isolates was subjected to an additional round of colony purification, and the isolated strain, designated “2GA,” was selected as a standard virus host for all following experiments, unless stated otherwise.
  • Cells of the 2GA isolate are rod-shaped, with an average length of about 4 μm and a width of about 0.7 μm.
  • ...1 more annotation...
  • A combination
Grant Reed

Study Finds Carrying Pollen Heats Up Bumble Bees, Raising New Climate Change Questions - 3 views

  • This new understanding of active bumble bee body temperatures raises questions about how these species will be impacted by a warmer world due to climate change.
    • Grant Reed
       
      Trying out the highlight feature. This might be an interesting research topic.
elijahjenkins

Fluorine-based new drug synthesis at lightning speed -- ScienceDaily - 0 views

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    Researchers synthesize fluorine-based compound via rapid biphasic (gas and liquid) mixing.
ryleighnyp

BMED010 - Natural and Commercial Moisturizers on Skin Model | Regeneron ISEF 2023 - 2 views

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    This is a good example of data collection, experimental design, and presentation.
ryleighnyp

The effects of grounding (earthing) on inflammation, the immune response, wound healing... - 2 views

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    This is something I'm interested in and it has lots of potential for projects.
ryleighnyp

Analyze This: Plants sound off when they're in trouble - 3 views

  • “We’ve shown only that plants emit informative sounds.”
    • ryleighnyp
       
      Do plants hear? Do they have "ears"?
ryleighnyp

Real-time dialogue between experimenters and dreamers during REM sleep: Current Biology - 3 views

  • study by Strauss and Dehaene13Strauss M. Dehaene S. Detection of arithmetic violations during sleep.Sleep (Basel). 2019; 42: zsy232PubMed Google Scholar focused on electro- and magnetoencephalographic responses to spoken arithmetic equations (addition, multiplication, or subtraction operations).
  • study by Strauss and Dehaene13Strauss M. Dehaene S. Detection of arithmetic violations during sleep.Sleep (Basel). 2019; 42: zsy232PubMed Google Scholar focused on electro- and magnetoencephalographic responses to spoken arithmetic equations (addition, multiplication, or subtraction operations).
    • ryleighnyp
       
      Magnetoencephalography is a technique used to measure the magnetic fields produced by electrical activity in the brain. It is a non-invasive method that can provide high temporal and spatial resolution of brain activity. In the context of the research paper, the authors mention a study by Strauss and Dehaene that focused on electro- and magnetoencephalographic responses to spoken arithmetic equations during wakefulness and sleep. (Copilot)
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    An interesting Sleep study about how scientist can communicate with people who are sleeping
Sean Nash

Hand dryers can infect clean hands with bathroom germs - 3 views

  • In tests, the hot-air machines spread far more microbes than paper towels
    • Sean Nash
       
      Another ISEF project from just last week!
katherine-medina

Native language differences in the structural connectome of the human brain - ScienceDi... - 1 views

  • elations (Friederici, 2011; Wilson et al., 2011). In this network, BA44 dominates syntactic processing while the IFS supports the processing of syntactic dependency relations in sentences
  • Phonetic information is processed in auditory areas in both hemispheres, and suprasegmental information,
  • dominant stem plus affix word
  • ...10 more annotations...
  • In particular, left BA 44
  • und morphemes
  • This suggests that Arabic language processing is also driven by the core language systems built in the IFG, posterior temporal, and IPL regions. In addition, cross-linguistic electrophysiological comparisons of Arabic and Spanis
  • electrophysiological
  • 2.6. Statistics
  • and suggests that white matter plasticity in brain structure coincides with specific cognitive functions and processing demands of life-long use of a particular language. Thus, our findings contribute to our understanding of the mechanisms underlying experience-dependent white matter organization and adaptation in the human brain
  • (Malik-Moraleda et al.,
  • Native speakers of Semitic languages may rely more on regions for spatial cognition in the right hemisphere
  • .4. Di
  • Additionally, social cognitive and affective processes and other non-linguistic factors may also lead to differences in the brain. In particular, cultural values such as individualism and collectivism have been shown to influence brain function.
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    How primary languages affect the brain (Arabic & German)
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    You will definitely want to use more than one tag when you save. Use all keywords, and be sure to click a few of the tags from the group dictionary that come up when you click to save to the HSR2023 group.
Sean Nash

New patch might replace some finger-prick testing of blood sugar - 2 views

  • Teen’s color-changing device tests glucose in sweat to signal when insulin is needed
    • Sean Nash
       
      This is from a 2023 ISEF project just last week!
Sean Nash

Regeneron ISEF 2023 - Finalist Project Portal - 6 views

  • Choose a category to begin
    • Sean Nash
       
      This is a really good way to dive into specific categories and explore the projects that made it to this year's ISEF. What I would do is start with what immediately interests you for now... and pick up some tips. You might get ideas for areas/topics to research. You might see creative methods used in various studies. Pay particular attention to the fact that some utilize equipment only available at a university or corporate lab, but... many also feature creative methods done by students at home or in school labs as well!
    • Sean Nash
       
      Once you get inside projects that you get ideas from, feel free to save them in Diigo for later, or share really interesting ones with others you think might benefit from seeing it.
    • Sean Nash
       
      One final thing: you might also get some tips for elements of their presentation that appeal to you.
Isabella Tungjaroenkul

Sci-Hub - 11 views

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    This shows current links pick one. When it opens copy paste the link of an article you want to read behind a pay wall. It will most likely have it.
katherine-medina

Using Meditation to Fight the Opioid Crisis | InnerScience Research Fund - 2 views

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    Kinda interesting to look at for what I am curious about
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