Dr. Goodyear

Study finds that increased free Testosterone is associated with increased incidence of prostate cancer.  Higher Total Testosterone was associated with lung cancer and androgens were not associated with colorectal cancer incidence.  That being said, the evaluation of androgens only is a significant limiting factor of this study.  

Low Testosterone is common among male cancer survivors after therapy.  Many studies point to low T at the time of diagnosis as a prognostic biomarker.  The low T impairs QOL in this men.

Colorectal cancer associated with decreased Testosterone levels in men.  This paper looked at total serum Testosterone.  The authors proposed that CEA plus Testosterone could be used in follow up.

Nitic Oxide (NO) via inflammation deactivates SIRT1 is a common finding in inflammatory diseases of aging, proposes authors of this paper.

Authors of this study postulate that "immune dysregulation" on the orders of autoimmune is likely involved in Meniere's disease.

study finds active Meniere's disease is associated with hypothyroidism.

Those with Meniere's disease found to have increased autoimmune disease.

Do weight loss drugs reduce obesity or could they actually increase obesity rates? The search for gimmicks has created a dependance on weight-loss drug falsehoods that don't work long term.  Life style has been and continues to be the long term answer.  Weight-loss drugs actually are fueling the obesity trend due to a lack of metabolic solutions.   They work for the health of pharma profits, just not for the health of the patient.

Study finds oral vitamin C and vitamin E hamper mitochondrial repair needed in exercise.  

Here is a study that goes against current dogma.  Ice in recovery for eccentric exercise slowed muscle damage repair and prolonged recovery.

review study finds protein at 0.4 to 0.5 g/kg of LBM pre and post work out maximizes the anabolic effect.

Oxidative stress markers remain elevated up to 5 days post ironman triathlon.

Recovery period of Ironman triathlon associated with significantly increased inflammatory response.  The vast majority is resolved by day 5 in this study, though low-grade inflammation persisted beyond day 5.  Cortisol was significantly elevated and Testosterone was significantly decreased in the early recovery period.  Muscle damage and significant inflammation is a prominent finding in the recovery phase of a triathlon.

Serum lactate elevates early in triathlon.  The greatest increase is associated with the swim event.  Muscle damage progressed through the 3 events (creatine phosphokinase and LDH).  Uric acid levels increased.  Recovery was seen out to 6 days post event.

Elevated ammonia depletes glutamate and BCCA in muscle and plasma.  A decrease in BCCA is through an up regulation of glutamine in an attempt to eliminate ammonia.

elevated ammonia levels reduce BCCA levels and increase glutamine levels in an attempt to eliminate ammonia.

Higher vitamin D levels associated with reduced mortality rates.

Swedish Cohort finds low sun exposure is associated with increased mortality.

Little if any conclusion can be drawn from this study.  There has actually been a call for redaction by experts in the field.

vitamin C effects decreased by hypoxia which increases HIF-1alpha.  The authors propose oxygen therapy, hyperbaric, to improve and augment the cytotoxic effects of vitamin C.