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Nathan Goodyear

Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communica... - 0 views

www.cell.com/...S0092-8674(13)01521-3

NAD mitochondria disease aging sirloins SIRT SIRT1 HIF-1alpha

shared by Nathan Goodyear on 07 Jun 16 - No Cached
  • Nathan Goodyear on 07 Jun 16
     
    NAD found to slow mitochondrial decline associated with aging.  SIRT1 is involved; interesting of note is the inverse association with HIF-1alpha
Nathan Goodyear

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to incr... - 0 views

stke.sciencemag.org/...ra106.abstract

nitric oxide NO inflammation SIRT1 sirloins disease aging

shared by Nathan Goodyear on 19 Nov 14 - No Cached
  • Nathan Goodyear on 19 Nov 14
     
    Nitic Oxide (NO) via inflammation deactivates SIRT1 is a common finding in inflammatory diseases of aging, proposes authors of this paper.
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