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Nitric oxide mediated erectile activity is a testosterone dependent event: a rat erecti... - 0 views

www.ncbi.nlm.nih.gov/...8770664 low T low Testosterone NO NOS nitric oxide Testosterone ED men male hormones
shared by Nathan Goodyear on 18 Nov 15 - No Cached
  • Nathan Goodyear on 18 Nov 15
     
    Only abstract available here, but rat model finds Testosterone increased NO synthase activity in corpora cavernous. 
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Androgen Deprivation Therapy and Future Alzheimer's Disease Risk - 0 views

jco.ascopubs.org/...JCO.2015.63.6266.abstract alzheimer's disease prostate cancer ADT androgen deprivation therapy male hormones Testosterone
shared by Nathan Goodyear on 09 Dec 15 - No Cached
  • Nathan Goodyear on 09 Dec 15
     
    new risk potential for Androgen Deprivation Therapy (ADT) for men with prostate cancer--increased Alzheimer's disease risk.
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Serum androgens and prostate cancer risk: results from the placebo arm of the Prostate ... - 0 views

www.ncbi.nlm.nih.gov/...26589415 prostate cancer prostate cancer Testosterone SHGB men male hormones
shared by Nathan Goodyear on 09 Dec 15 - No Cached
  • Nathan Goodyear on 09 Dec 15
     
    study finds no association between total Testosterone, free Testosterone, and 3alpha-andorstanediol glucuronide and prostate cancer.  Included: no association with SHBG and estrogen to Testosterone ratio.
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Prospective longitudinal study of testosterone and incident depression in older men: Th... - 0 views

www.ncbi.nlm.nih.gov/...26615472 low Testosterone Testosterone depression men male hormones low T
shared by Nathan Goodyear on 09 Dec 15 - No Cached
  • Nathan Goodyear on 09 Dec 15
     
    low Total Testosterone is associated with depression in oder men.
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Effects of aromatase inhibition vs. testosterone in older men with low testosterone: ra... - 0 views

www.ncbi.nlm.nih.gov/...26588809 low T low Testosterone Testosterone testosterone therapy aromatase inhibitors aromatase inhibition aromatase inhibitor aromatase men male hormones strength muscle mass muscle bone mineral density
shared by Nathan Goodyear on 07 Dec 15 - No Cached
  • Nathan Goodyear on 07 Dec 15
     
    No surprise that Testosterone therapy improves Testosterone levels in men with low T, but aromatase inhibition (AI) did as well.  In this study, only lean mass increased compared to Testosterone therapy and placebo.  Strength increased in both Testosterone and AI.
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Normalization of testosterone level is associated with reduced incidence of myocardial ... - 0 views

eurheartj.oxfordjournals.org/...2706 low T low Testosterone Testosterone Testosterone therapy mortality MI stroke heart men male hormones
shared by Nathan Goodyear on 18 Jan 16 - No Cached
  • In this study of men with low TT levels and without prior MI or stroke, normalization of TT levels using TRT is associated with lower all-cause mortality, fewer MIs, and ischaemic strokes.
  • retrospective study
  • significant benefit is observed only if the dose is adequate to normalize the TT levels
  • ...9 more annotations...
  • the mechanisms for these effects remain speculative
  • It can be postulated that the beneficial effect of normal T levels on adipose tissue, insulin sensitivity, and lipid profiles or by its anti-inflammatory and anticoagulant properties, as reported by other investigators, might have contributed to our findings
  • off-label use of TRT remains a concern
  • Recent FDA analyses suggest that currently only half of the men on TRT had been diagnosed with hypogonadism
  • 25% of users did not have their T concentrations tested prior to initiating therapy
  • 21% of those prescribed TRT did not have their levels tested at any time during treatment
  • two very recent meta-analyses suggested a lack of convincing evidence posed by TRT.
  • men without a history of previous MI or stroke who have low TT levels, TRT might be associated with decreased risks of MI, ischaemic stroke, and all-cause mortality in long-term follow-up
  • TRT should aim for doses resulting in normalization of TT level as this was shown to be associated with reduction in adverse CV events
  • Nathan Goodyear on 18 Jan 16
     
    Testosterone therapy in men with low T to restore physiologic Testosterone levels found to reduce mortality, MI, and stroke risk.
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healthy skin | Get Beauty Tips On - 0 views

beautybycagla.com/...healthy-skin hormones Testosterone cancer Men inflammation obesity Male low Disease
shared by beautybycagla on 24 Mar 19 - No Cached
  • beautybycagla on 24 Mar 19
     
    As we get older, it is importаnt for us to tаke decent cаre of our skin. Exposure to sunlight аnd elements thаt аre distinct cаn wreаk hаvoc on it. This mаy leаd to premаture аging аnd other skin conditions. A skin cаre routine will surely help keep our skin looking fresh, young аnd hydrаted. These аre importаnt steps thаt you need to do аnd so, without further аdo, here is your guide to some bаsic skin cаre routine.
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Modern Times Helpline Pharma - Exporter of Gefitinib Medicines & Erlotinib Tablets from... - 1 views

www.moderntimesindia.com hormones cancer disease Male inflammation Testosterone Gefitinib Medicines Erlotinib Tablets Sorafenib Tosylate Imatinib Mesylate Bortezomib Injection Pirfenidone Temozolomide Capsules New_Delhi
shared by mthlp2019 on 02 Jan 19 - No Cached
  • mthlp2019 on 02 Jan 19
     
    Gefitinib Medicines, Erlotinib Tablets & Sorafenib Tosylate Exporter offered by Modern Times Helpline Pharma from New Delhi, Delhi, India
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Testosterone replacement therapy and the risk of prostate cancer - 0 views

www.ncbi.nlm.nih.gov/...PMC4814970 Testosterone testosterone therapy saturation theory cancer prostate cancer male hormones
shared by Nathan Goodyear on 01 Oct 16 - No Cached
  • When the level of circulating androgen is below normal, some androgen receptors are inactive, and the secondary downstream effects are decreased. Once androgen receptors within the prostate are saturated, however, increasing testosterone will no longer have an effect
  • the saturation point is thought to occur at low physiologic testosterone levels
  • Only the subset of individuals with pretreatment testosterone level <250 ng dl−1 had PSA level correlating with free and total testosterone level
  • ...7 more annotations...
  • none of the men stopped testosterone supplementation due to prostate cancer recurrence, and none demonstrated cancer progression
  • PSA level did transiently rise in one patient; however, none exceeded a PSA of 1.5 ng ml−1 to raise concern for biochemical recurrence
  • after 19 months on TRT, 10 hypogonadal patients with a history of undergoing a radical retropubic prostatectomy for prostate cancer had no PSA recurrence and had statistically significant improvements in serum total testosterone and hypogonadal symptoms
  • Similarly, Kaufman and Graydon14 examined case records of seven hypogonadal men who had undergone curative RP with symptoms of hypogonadism and low serum testosterone levels treated with testosterone replacement. No biochemical or clinical evidence of cancer recurrence was noted
  • In a much larger case series, Khera et al.15 reviewed the records of 57 men who received TRT following RP. After an average of 36 months following RP, testosterone replacement was initiated and followed for an average of 13 months. Mean testosterone values rose significantly and once again, there was no increase in PSA values and, therefore, no diagnosed biochemical recurrence
  • Four of the patients in the treatment group were found to have cancer recurrence, compared with eight in the control group
  • All biochemical recurrences were seen in individuals with high-risk disease
  • Nathan Goodyear on 01 Oct 16
     
    Good review of data on Testosterone therapy and prostate cancer risk: the take home is there is no increased risk.  Also, included is a discussion of the prostate saturation theory.
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Testosterone administration to men with testosterone deficiency syndrome after external... - 0 views

www.ncbi.nlm.nih.gov/...18671790 Testosterone low T low Testosterone men male hormones prostate cancer cancer saturation theory prostate
shared by Nathan Goodyear on 10 Oct 16 - No Cached
  • Nathan Goodyear on 10 Oct 16
     
    small study of men post prostate cancer radiotherapy: only 1 of the 5 had a transient rise in PSA, though the level was still below the 1.5 ng/ml threshold.  This fits within the saturation theory concept. F/u in this study was 14.5 months.  Abstract only available here.
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Liver damage from long-term methyltestosterone. - PubMed - NCBI - 1 views

www.ncbi.nlm.nih.gov/69876 liver Testosterone male hormones
shared by Nathan Goodyear on 22 Aug 16 - No Cached
  • Nathan Goodyear on 22 Aug 16
     
    oral methyl Testosterone associated with liver dysfunction and damage. This does not appear to apply to topical or IM Testosterone.  This risk is unique to oral methyl Testosterone.
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Testosterone therapy in hypogonadal men and potential prostate cancer risk: a systemati... - 0 views

www.ncbi.nlm.nih.gov/...PMH0027131 low T low Testosterone Testosterone testosterone therapy cancer prostate cancer male hormones
shared by Nathan Goodyear on 01 Oct 16 - No Cached
  • Nathan Goodyear on 01 Oct 16
     
    meta-analysis finds no evidence of testosterone therapy and increased risk of prostate cancer.
1More

Penis enlargement due to where? Cause And Treatment - 1 views

trungtamnamkhoa.com/n-duong-vat-noi-mun-trang.html penis pimples white acne male men health healthy cancer Testosterone hormone
shared by trungtamnamkhoa on 25 Jun 19 - No Cached
  • trungtamnamkhoa on 25 Jun 19
     
    The body of the white pimples is a common feature of boys entering puberty. Understanding their nature will help you no longer worry. White pimples on the penis and pores, squeezing out with a white core. Do these acne affect fertility? This top concern in many young people will be answered right after.
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A Perspective on Middle-Aged and Older Men With Functional Hypogonadism: Focus on Holis... - 0 views

www.ncbi.nlm.nih.gov/...28359097 low T low Testosterone lifestyle intervention hypogonadism male hormones
shared by Nathan Goodyear on 27 Apr 17 - No Cached
  • Nathan Goodyear on 27 Apr 17
     
    literature review finds that lifestyle interventions can improve Testosterone levels in men.  For many men, low Testosterone, is the result not the cause.
  • Open TeleShop on 17 May 17
     
    Hey Dear Check Out Our Online Shopping store in all Over Pakistan.As Seen as On Tv Products Like as Health Beauty,Fitness,Homeware,Kitchenware,And Other Electronic Products in Pakistan Check Out Now| www.openTeleshop.Com
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Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-tr... - 0 views

www.ncbi.nlm.nih.gov/...18522674 low Testosterone Testosterone male hormones inflammation LPS lipopolysaccharides
shared by Nathan Goodyear on 13 Apr 17 - No Cached
  • Nathan Goodyear on 13 Apr 17
     
    Animal study from '09 found that COX2 inhibitor blunted LPS decrease in testes weight, decrease in testicular interstitial fluid, and serum Testosterone.  The point here is that LPS, in this animal model, decreased gonadal weight and Testosterone production and the anti inflammatory, COX2, blunted that effect.
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Efficacy and Safety of an Injectable Combination Hormonal Contraceptive for Men | The J... - 0 views

academic.oup.com/...jc.2016-2141 Testosterone contraception male contraception
shared by Nathan Goodyear on 22 Sep 17 - No Cached
  • Nathan Goodyear on 22 Sep 17
     
    Study finds injectable contraception in men leaves delayed suppressed LH and Testosterone. This drug design is by those devoid of overall knowledge of physiology. Lower Testosterone in men has significant negative metabolic effect, neurotransmitter impact, and what about epigenetics. Some men have epigenetically increased risk of hypogonadism. This contraception is a bad idea physiologically.
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