Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway - 0 views
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Nathan Goodyear on 16 Apr 18Niclosamide, a common antilemintic/anti-parasitic medication, inhibits Wnt/Beta-catenin signaling involved in carcinogenesis and metastasis. the mechanism is through LRP6 degradation to provide antiproliferative and apoptosis activity.