Evolution of the Cancer Stem Cell Model: Cell Stem Cell - 0 views
-
cancer is widely understood to be a heterogeneous disease and there is increasing awareness that intratumoral heterogeneity contributes to therapy failure and disease progression
-
Evidence from both experimental models and clinical studies indicate that CSCs survive many commonly employed cancer therapeutics
-
both CSCs and normal tissue stem cells possess self-renewal capacity; however, self-renewal is typically deregulated in CSCs
- ...2 more annotations...