Evolution of the Cancer Stem Cell Model: Cell Stem Cell - 0 views
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cancer is widely understood to be a heterogeneous disease and there is increasing awareness that intratumoral heterogeneity contributes to therapy failure and disease progression
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Evidence from both experimental models and clinical studies indicate that CSCs survive many commonly employed cancer therapeutics
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the properties and transcriptional signatures specific to CSC are highly predictive of overall patient survival pointing to their clinical relevance
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