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Nathan Goodyear

Assessment of the safety of supplementation with different amounts of vitamin E in heal... - 0 views

ajcn.nutrition.org/...311.abstract

vitamins vitamin E alternative medicine safety

shared by Nathan Goodyear on 13 Jun 16 - No Cached
  • Nathan Goodyear on 13 Jun 16
     
    Vitamin E supplementation in individuals >65 for 4 months on dosing up to 800 IU not found to have adverse events as described as decreased platelets, prolonged bleeding time, lower hemoglobin/hematocrit...
Nathan Goodyear

Glutathione (GSH) improved haemostatic an... [Drugs Exp Clin Res. 1992] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...1308476

IV glutathione therapy treatment atherosclerosis CVD

shared by Nathan Goodyear on 10 Nov 11 - No Cached
  • Nathan Goodyear on 10 Nov 11
     
    IV glutathione shown to reduce blood viscosity and platelet aggregation.  THis has major implications in atherosclerosis and CVD
Nathan Goodyear

Nutrition Journal | Full text | Homocysteine and reactive oxygen species in metabolic s... - 0 views

www.nutritionj.com/4

homocysteine atherogenesis CVD metabolic syndrome metabolic syndrome

shared by Nathan Goodyear on 23 Jul 12 - No Cached
  • Nathan Goodyear on 23 Jul 12
     
    homocysteine contributes to atherogenesis and CVD via: increased ROS, induces endothelial dysfunction, increases platelete adhesion and thrombosis, increases smooth muscle cell proliferation, endothelial cell cytotoxicity, increases LDL oxidation, vasoconstriction, increased MCP-1 and IL-8, and induces endothelial HMG CoA reductase.
Nathan Goodyear

Differential regulation of endothelium behavior by progesterone and medroxyprogesterone... - 0 views

joe.endocrinology-journals.org/...179.abstract

progesterone medroxyprogesterone acetate medroxyprogesterone hormone hormones women cardiovascular disease HRT

shared by Nathan Goodyear on 04 Feb 14 - No Cached
  • Nathan Goodyear on 04 Feb 14
     
    No surprise that progesterone and the synthetic progestin medroxyprogesterone acetate (MPA) have different effects on the vascular endothelium. MPA inhibits NO production, whereas Progesterone maintains NO production.  MPA promoted platelet adhesion whereas Progesterone did not--significant implication in plaque formation.
Nathan Goodyear

Testosterone Increases Human Platelet Thromboxane A2 Receptor Density and Aggregation R... - 0 views

circ.ahajournals.org/...2742.full

testosterone thrombaxane A2 TXA2 plateletes

shared by Nathan Goodyear on 06 Nov 13 - No Cached
  • Nathan Goodyear on 06 Nov 13
     
    Thrombaxane A2 increased by Testosterone in small study.  This is a human study.
Nathan Goodyear

High D-dimer levels are associated with poor prognosis in cancer patients - 0 views

www.ncbi.nlm.nih.gov/...PMC3409812

cancer D-dimer

shared by Nathan Goodyear on 10 Jul 18 - No Cached
  • a systemic activation of blood coagulation and procoagulant changes in the hemostatic system have frequently been observed in cancer patients, even in the absence of venous thromboembolism
  • Thrombin is a pivotal enzyme in the process of blood coagulation and leads to the conversion of fibrinogen to fibrin, which is the end product of blood coagulation and finally results in the formation of a fibrin clot
  • deposition of fibrin, which has an important role in the formation of tumor stroma and hematogenous spread of tumor cells.
  • ...5 more annotations...
  • The interaction of fibrin, platelets and tumor cells leads to the formation of platelet-fibrin-tumor-cell aggregates that promote endothelial adhesion and metastatic spread, as well as tumor cell growth and tumor cell survival
  • fibrin degradation products have been shown to display strong angiogenic properties
  • D-dimer is a biomarker that globally indicates the activation of hemostasis and fibrinolysis
  • It is a degradation product of fibrin
  • high D-dimer levels were reported to be predictive of the occurrence of VTE in cancer patients
  • Nathan Goodyear on 10 Jul 18
     
    elevated D-Dimer associated with poor prognosis in cancer. Good review of cancer and ehmostasis.
fnfdoc

Symptoms Of Aplastic Anemia | Your Health Our Priority - 0 views

www.fnfdoc.com/...symptoms-aplastic-anemia

Acquired Aplastic Anemia Inherited

shared by fnfdoc on 09 May 18 - No Cached
  • fnfdoc on 09 May 18
     
    Aplastic Anemia is a rare but serious disease of the blood cells. It is diagnosed by the inability of the bone marrow to synthesize RBCs, WBCs and platelets. The spongy bone marrow contains stem cells that are actively involved in Hematopoiesis.
Nathan Goodyear

Changes in neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios during chemoradia... - 0 views

www.ncbi.nlm.nih.gov/...PMC4783757

neutrophil to lymphocyte ratio platelets to lymphocyte ratio NLR cancer PLR neutroph

shared by Nathan Goodyear on 31 Mar 20 - No Cached
  • Nathan Goodyear on 31 Mar 20
     
    Increased NLR and PLR Associated with poor/worse prognosis.
Nathan Goodyear

Metastasis: new functional implications of platelets and megakaryocytes | Blood | Ameri... - 0 views

ashpublications.org/...new-functional-implications-of

platelets cancer metastasis

shared by Nathan Goodyear on 25 Aug 21 - No Cached
  • Nathan Goodyear on 25 Aug 21
     
    To be read
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