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Nathan Goodyear

The Effect of Fluoride on the Physiology of the Pineal Gland - 0 views

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    Flouride appears to decrease melatonin production from the pineal gland.   Flouride was associated with early puberty and accelerated development
Nathan Goodyear

http://www.imedpub.com/articles/five-yearsurvival-with-highdose-melatonin-and--other-an... - 0 views

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    High dose melatonin in the immune treatment of cancer. A must read.
Nathan Goodyear

Melatonin inhibits both ER alpha activation and... [J Pineal Res. 2006] - PubMed - NCBI - 0 views

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    Several interesting points about this article.  Cadmium is a non-carcinogen.  Cadmium acts through estrogen receptors.  Cd acts as an estrogen.  Second, melatonin inhibits ER alpha, which promotes inflammation and growth signaling.
Nathan Goodyear

Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic f... - 0 views

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    melatonin appears to help in weight loss and improve LDL and HDL cholesterol levels
Nathan Goodyear

Beneficial effects of melatonin on obesity and lip... [J Pineal Res. 2011] - PubMed result - 0 views

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    Melatonin beneficial for weight loss in diabetic rat model 
Nathan Goodyear

Melatonin and Cortisol assessment of circadian shifts in astronauts before flight - Whi... - 0 views

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    Melatonin and Cortisol salivary testing by NASA
Nathan Goodyear

Efficacy of the concomitant administration of the pineal hormone melatonin in cancer im... - 0 views

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    melatonin found to enhance the IL-2 anti-tumor activity in preliminary study.
Nathan Goodyear

A phase II study of chemoneuroimmunotherapy with platinum, subcutaneous low-dose interl... - 0 views

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    Low dose cisplatin, low dose IL-2 and high dose melatonin as effective as first line therapy in the treatment of melanoma
Nathan Goodyear

Immunotherapy with subcutaneous low-dose interleukin-2 and the pineal indole melatonin ... - 0 views

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    study on melatonin and IL2 in cancer
Nathan Goodyear

A phase II study of neuroimmunotherapy with subcutaneous low-dose IL-2 plus the pineal ... - 0 views

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    Abstract only here.  Immunotherapy of IL-2 + melatonin provided lack of progression of 67% of patients included with a average duration of 21+ months in patients with untreatable advanced hematologic cancer.  Again, no toxicities.  Interesting, the survival time was similar to the previously reported survival times with the highly toxic high dose IL-2 therapy.
Nathan Goodyear

Prevention of interleukin-2-induced thrombocytopenia during the immunotherapy of cancer... - 0 views

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    Only abstract available here to general public.  Thrombocytopenia is associated with IL-2 therapy.  Melatonin found to block this effect when used in conjunction with IL-2 therapy.  Alone, melatonin did not increase platelet levels.  The proposed mechanism is an inhibition of macrophage mediated destruction of plateletes.
Nathan Goodyear

Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Me... - 0 views

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    dopamine inhibits melatonin production and release disrupting sleep.
Nathan Goodyear

The role of melatonin in the cells of the innate immunity: a review - Calvo - 2013 - Jo... - 0 views

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    Melatonin is a powerful stimulant to the innate immune system.
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