Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer... - 0 views
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More than half of cancer patients are treated with IR at some point during their treatment
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fractionation schedule is the delivery of 1.8–2.0 Gy per day, five days per week
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Nuclear DNA is the primary target of IR; it causes DNA damage (genotoxic stress) by direct DNA ionization
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Tumor regionalization after surgery: Roles of the tumor microenvironment and neutrophil... - 0 views
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tumor surgery must be carefully considered because the risk of metastasis could be increased by the surgical procedure.
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NETosis, which is the process of forming neutrophil extracellular traps (NETs)
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surgery-induced metastasis
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LeanBiome™ (Official) | Get Save UpTo $540 Today Only! - 0 views
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LeanBiome™ (Official) | Get Save UpTo $540 Today Only! usleanbiome.com LeanBiome™ Hurry Up! Offer Expires in: 00 HOUR 29 MINUTE 59 SECOND LeanBiome Attention! Get Special 84% Discount Today Faster fat burning and weight loss Healthy cholesterol and sugar levels Higher energy levels Regular price: $129 Only for: 39$ What Is LeanBiome? LeanBiome Lean for Good is a weight loss dietary supplement derived from scientifically researched ingredients and comprehensively developed to help people achieve sustainable weight control. The formula comes in a capsule format that is easy to take and is made with natural ingredients from plants and other sources to achieve its goals. The main ingredient in LeanBiome is piperine, which has been found to affect the body's ability to absorb micronutrients and other compounds more effectively. LeanBiome is a dietary supplement that claims to help weight management. It contains 100% natural ingredients that support healthy weight loss. It does not interfere with any natural process making it safe for use. It ranks among the top weight loss supplements that claim to provide a permanent solution. LeanBiome is made by a company named Lean for Good. It is made with natural and research-backed ingredients that help you lose excess fat without hassles. It is sold in capsule form. The company assures the composition is GMO, gluten, and soy-free. As for manufacturing standards, you need not fret. The company makes the supplement in a facility certified by the FDA. How Does LeanBiome Work? The starting period of the LeanBiome program includes a detoxification process that effectively removes any accumulated ree radicals, toxins, fand oxidative stress. This cleansing enables improved blood circulation, setting the stage for the body to initiate its own fat-burning mechanisms. To enhance metabolic activity, introducing the lean bacteria contained in LeanBiome to your gut microbiome is a beneficial approach. This activation triggers r
Testosterone: a vascular hormone in health and disease - 0 views
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Testosterone has beneficial effects on several cardiovascular risk factors, which include cholesterol, endothelial dysfunction and inflammation
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In clinical studies, acute and chronic testosterone administration increases coronary artery diameter and flow, improves cardiac ischaemia and symptoms in men with chronic stable angina and reduces peripheral vascular resistance in chronic heart failure.
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testosterone is an L-calcium channel blocker and induces potassium channel activation in vascular smooth muscle cells
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Potent Inhibition of Human Phosphodiesterase-5 by Icariin Derivatives - Journal of Natu... - 0 views
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A natural phosphodiesterase 5 inhibitor would be nice. This study looked at a lot of traditional herbal remedies to block phosphodiesterase 5 activity. Only Epimedii herb with the active ingredient icariin worked. Other preparations were shown to work, but via different mechanisms. This is a review of studies looking at these herbal preparations.
Metabolic management of brain cancer - 0 views
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Glutamine is a major metabolic fuel for both brain tumor cells and tumor-associated macrophages (TAMs)
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the malignant phenotype of brain tumor cells that survive radiotherapy is often greater than that of the cells from the original tumor.
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Conventional chemotherapy has faired little better than radiation therapy for the long-term management of malignant brain cancer
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Testosterone: a metabolic hormone in health and disease - 0 views
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E2 and the inflammatory adipocytokines tumour necrosis factor α (TNFα) and interleukin 6 (IL6) inhibit hypothalamic production of GNRH and subsequent release of LH and FSH from the pituitary
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Leptin, an adipose-derived hormone with a well-known role in regulation of body weight and food intake, also induces LH release under normal conditions via stimulation of hypothalamic GNRH neurons
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In human obesity, whereby adipocytes are producing elevated amounts of leptin, the hypothalamic–pituitary axis becomes leptin resistant
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Chemistry and Structural Biology of Androgen Receptor - 0 views
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Healthy adult men typically produce approximately 3–10 mg of testosterone per day
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circulating levels ranging from 300 to 700 ng/dL in eugonadal men
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endogenous testosterone secretion is pulsatile and diurnal
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Natural Killer Cells in Pregnancy and Recurrent Pregnancy Loss: Endocrine and Immunolog... - 0 views
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NK cells have been the cells most extensively studied, primarily because they constitute the predominant leukocyte population present in the endometrium at the time of implantation and in early pregnancy
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parental chromosomal abnormalities, uterine anatomic anomalies, endometrial infections, endocrine etiologies (luteal phase defect, thyroid dysfunction, uncontrolled diabetes mellitus), antiphospholipid syndrome, inherited thrombophilias, and alloimmune causes
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estrogen
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Redefining Metabolic Syndrome in Men (July 2012) Townsend Letter for Doctors & Patients - 0 views
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Approximately 95% to 98% of testosterone is bound to a carrier protein at any given time, leaving just the remaining 2% to 5% as completely unbound and available for tissues to use
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most serum laboratories offer a free testosterone level, which is a calculated value based on SHBG levels or determined with equilibrium dialysis
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the hormone enters the salivary gland by passive diffusion
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