Group items tagged

low T is found in 20-70% of men with HIV.  What is interesting about this article is that Total Testosterone was found to be a poor assessment of biological active Testosterone.  Free Testosterone assessed in the am was shown to be a better functional assessment in these men.  Serum is a poor choice though.  The process of equilibrium dialysis to calculate free Testosterone is filled with variables that will effect reliability.  Increases SHBG was found associated.

Very interesting study finds that a single value assessment of androgens, DHEAS, prolactin, IGF-1 and IGFBP-3 can be used to assess 3 year average in pre-menopause women.  Estrogen and progesterone need to be assessed through the cycle.

study suggests biomarkers, CHDRA, with history provides good 5 year CHD risk assessment among those with intermediate risk.

Coronary artery calcium is positively associated with CAD risk.  It compares to multiple biomarker assessment, BNP, and homocysteine assessment.

study finds no increased risk of CHD, HF, or CV death in subclinical hypothyroidism in older adults.  No insight is gained from this article, due to the use of TSH as the only tool for thyroid assessment.  TSH has been shown to become unreliable as a sole thyroid assessment tool an aging population.

salivary cortisol shown to accurately reflect the systemic cortisol burden.  This study concluded that saliva cortisol was an accurate assessment tool for the free, biological cortisol in the body.  Saliva an appropriate assessment tool, in the place of serum.

prospective study of almost 9,000 men and women followed for 30 + years.  The study found that there was a significant increased risk of early death after diagnosis of cancer with higher levels of Testosterone.  The risk was increased by up to 80%.  The incidence of cancer was unchanged.  The study looked at total Testosterone via serum.  The study is limited due to its limited look at hormones.  Full Testosterone metabolism needs to be evaluated--including conversion to estrogens.  Inflammatory cytokines need to be assessed and men and women need to be assessed separately as their reactions to hormones are quite different.

salivary estradiol and progesterone used to assess women with infertility

assessing cortisol and DHEA in saliva

Interesting study looked at Total Testosterone (TT) and free Testosterone (FT) in older men in BMD assessment.  The authors found no change in TT, but a significant decline in free Testosterone.  This fits with other research pointing to free Testosterone as a better functional assessment tool.

What Are the Steps Related to Clinical Assessments? What's incorrect with Cynthia? There are several factors that can cause forgetfulness.

Good review of the SUVs of a PET/CT scan.

Salivary cortisol for assessment of hypothalamic-pituitary-adrenal axis function.

Steroid Analysis in Saliva for the Assessment of Endocrine Function

A revolution in biomedical assessment: the development of salivary diagnostics.

Salivary steroid assays for assessing variation in endocrine activity.

saliva cortisol testing "widely" accepted in 1984

The use of salivary progesterone assays in the assessment of ovarian function in postmenarcheal girls

salivary estriol to assess preterm labor

saliva cortisol testing is a better assessment tool for HPA axis function, compared to serum cortisol