Tumor regionalization after surgery: Roles of the tumor microenvironment and neutrophil... - 0 views
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tumor surgery must be carefully considered because the risk of metastasis could be increased by the surgical procedure.
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NETosis, which is the process of forming neutrophil extracellular traps (NETs)
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surgery-induced metastasis
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Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer ... - 0 views
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HCQ, doses for long-term use range between 200 and 400 mg per day.
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Short-term administration of CQ or HCQ rarely causes severe side effects
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Short-term administration of CQ or HCQ rarely causes severe side effects
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The effects of surgery on plasma/serum vitamin C concentrations: a systematic review an... - 1 views
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and h... - 0 views
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Proposed mechanism
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The data show that pharmacologic ascorbate concentrations produced Asc•− selectively in extracellular fluid compared with blood and that H2O2 formation occurred when Asc•− concentrations were >100 nM in extracellular fluid.
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These data validate the hypothesis that ascorbate is a prodrug for selective delivery of reactive species to the extravascular space
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