Sex hormones as immunomodulators in heal... [Int Immunopharmacol. 2001] - PubMed - NCBI - 0 views
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Nathan Goodyear on 31 Jul 13Estradiol in mice predisposed to Lupus have increased inflammation and characteristics of Lupus. In contrast, Estradiol in those without predisposition, do not. Clearly this is an inflammatory signaling problem. Studies have shown an Interferon gamma signaling deficit in those with Lupus. Testosterone decreases the above inflammation signaling.