Group items tagged tumor immunologic microenvironment - Dr. Goodyear

Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for No... - 0 views

www.nature.com/...srep13110

PD-1 cancer check point inhibitors PD-L1 CLTA-4 immunotherapy

shared by Nathan Goodyear on 20 Apr 18 - No Cached

the lack of immunologic control is recognized as a hallmark of cancer currently
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Programmed death-1 (PD-1) and its ligand PD-L1 play a key role in tumor immune escape and the formation of tumor microenvironment, closely related with tumor generation and development
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Blockading the PD-1/PD-L1 pathway could reverse the tumor microenvironment and enhance the endogenous antitumor immune responses.
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environmental factors, living habits, genetic mutations, dysfunction of the immune system and so on
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special tumor immune microenvironment
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cytotoxic T lymphocyte-associated antigen 4 (CLTA-4), Programmed death-1 (PD-1) and its ligands PD-L1 (B7H1) and PD-L2 (B7-DC)
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CTLA-4 regulates T cell activity in the early stage predominantly, and PD-1 mainly limits the activity of T-cell in the tumor microenvironment at later stage of tumor growth
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Nathan Goodyear on 20 Apr 18

PD-1 to read.

<div class="cArrow"> </div><div class="cContentInner">PD-1 to read.</div>

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Manipulating the Immunological Tumor Microenvironment | Frontiers Research Topic - 0 views

www.frontiersin.org/...logical-tumor-microenvironment

tumor microenvironment cancer TME

shared by Nathan Goodyear on 25 Feb 21 - No Cached

Nathan Goodyear on 25 Feb 21

Additional studies on TME to read

<div class="cArrow"> </div><div class="cContentInner">Additional studies on TME to read</div>

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Immune suppression and reversal of the suppressive tumor microenvironment | Internation... - 0 views

academic.oup.com/...5043264

immunology immunotherapy cancer cancer TME immunomodulation immunotherapy tumor microenvironment immunosuppression

shared by Nathan Goodyear on 14 Mar 21 - No Cached

Nathan Goodyear on 14 Mar 21

To be read

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High and low mutational burden tumors versus immunologically hot and cold tumors and re... - 0 views

jitc.biomedcentral.com/...s40425-018-0479-7

hot tumors cancer tumor microenvironment cold tumors TME

shared by Nathan Goodyear on 02 Aug 23 - No Cached

Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immun... - 0 views

www.sciencedirect.com/...S1044579X17300366

TME cancer tumor microenvironment acid tumor cancer acidic pH

shared by Nathan Goodyear on 19 Apr 20 - No Cached

Nathan Goodyear on 19 Apr 20

Acidic pH in TME favors cancer growth and spread immunologically.

<div class="cArrow"> </div><div class="cContentInner">Acidic pH in TME favors cancer growth and spread immunologically.</div>

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Understanding the tumor immune microenvironment (TIME) for effective therapy - 0 views

www.ncbi.nlm.nih.gov/...PMC5998822

cancer tumor immunologic microenvironment

shared by Nathan Goodyear on 29 May 21 - No Cached

Frontiers | Hyperthermia Targeting the Tumor Microenvironment Facilitates Immune Checkp... - 0 views

www.frontiersin.org/...full

TME hyperthermia cancer tumor microenvironment check point inhibitors

shared by Nathan Goodyear on 24 Feb 21 - No Cached

Improving immunological tumor microenvironment using electro-hyperthermia followed by d... - 0 views

bmccancer.biomedcentral.com/...s12885-015-1690-2

Hyperthermia tumor microenvironment TME

shared by Nathan Goodyear on 25 Feb 21 - No Cached

Nathan Goodyear on 25 Feb 21

To be read

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Frontiers | Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Tu... - 0 views

www.frontiersin.org/...full

Tumor associate macrophages CD8 tumor microenvironment TAMs metronomic chemotherapy NK cells cancer low-dose chemotherapy

shared by Nathan Goodyear on 09 Oct 20 - No Cached

TGFβ signaling plays a critical role in promoting alternative macrophage acti... - 0 views

bmcimmunol.biomedcentral.com/...1471-2172-13-31

tumor microenvironment TGF-beta M2 macrophages M2 TME

shared by Nathan Goodyear on 02 Oct 20 - No Cached

Nathan Goodyear on 02 Oct 20

TGF-beta promotes M2 polarization through epigenetic expression that effects TME and tumor growth potential.

<div class="cArrow"> </div><div class="cContentInner">TGF-beta promotes M2 polarization through epigenetic expression that effects TME and tumor growth potential.</div>

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The complex role of tumor-infiltrating macrophages | Nature Immunology - 0 views

www.nature.com/...s41590-022-01267-2

Tumor associate macrophages tumor microenvironment cancer TAMs

shared by Nathan Goodyear on 23 Aug 22 - No Cached

Frontiers | Hypoxic Characteristic in the Immunosuppressive Microenvironment of Hepatoc... - 0 views

www.frontiersin.org/...full

cancer tumor microenvironment TME immunosuppression hypoxia

shared by Nathan Goodyear on 17 Feb 21 - No Cached

[Full text] The role of regulatory T cells in cancer immunology | ITT - 0 views

www.dovepress.com/-reviewed-fulltext-article-ITT

cancer T regulatory cells tumor microenvironment T regulator cells T reg

shared by Nathan Goodyear on 08 Nov 20 - No Cached

Frontiers | Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and... - 0 views

www.frontiersin.org/...full

MDSC tumor microenvironment cancer myeloid-derived suppressor cells TME NK cells

shared by Nathan Goodyear on 21 Nov 20 - No Cached

Frontiers | Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumo... - 0 views

www.frontiersin.org/...full

immune system angiogenesis NK cells VEGF cancer

shared by Nathan Goodyear on 03 Oct 20 - No Cached

Cancers | Free Full-Text | Mechanisms of Immunosuppression in Colorectal Cancer | HTML - 0 views

www.mdpi.com/...htm

immunotherapy tumor microenvironment cancer TME immunology

shared by Nathan Goodyear on 14 Mar 21 - No Cached

Nathan Goodyear on 14 Mar 21

To be read

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NF-κB, an Active Player in Human Cancers | Cancer Immunology Research - 0 views

cancerimmunolres.aacrjournals.org/...823

tumor microenvironment NF-kappaB angiogenesis metastasis

shared by Nathan Goodyear on 10 Jan 21 - No Cached

Nathan Goodyear on 10 Jan 21

NF-kappaB plays integral role in carcinogenesis

<div class="cArrow"> </div><div class="cContentInner">NF-kappaB plays integral role in carcinogenesis</div>

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Improving immunological tumor microenvironment using electro-hyperthermia followed by d... - 0 views

www.ncbi.nlm.nih.gov/...PMC4608323

dendritic cells dendritic cell vaccines dendritic cell vaccine hyperthermia cancer

shared by Nathan Goodyear on 14 Aug 20 - No Cached

Nathan Goodyear on 14 Aug 20

Thoughts for effective immune treatment.

<div class="cArrow"> </div><div class="cContentInner">Thoughts for effective immune treatment.</div>

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Frontiers | Modulators of the Balance between M1 and M2 Macrophages during Pregnancy | ... - 0 views

www.frontiersin.org/...full

immune system tumor microenvironment M1 macrophages M2 macrophages TME M1 Pregnancy M2

shared by Nathan Goodyear on 02 Oct 20 - No Cached

Nathan Goodyear on 02 Oct 20

Great review of M1 and M2 polarization in pregnancy. The implication for me is the impact in the TME in cancer and its contribution to physical and immune escape.

<div class="cArrow"> </div><div class="cContentInner">Great review of M1 and M2 polarization in pregnancy. The implication for me is the impact in the TME in cancer and its contribution to physical and immune escape.</div>

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Frontiers | Learning from the microbes: exploiting the microbiome to enforce T cell imm... - 0 views

www.frontiersin.org/...full

immunotherapy cancer TME microbiome tumor microenvironment immunology

shared by Nathan Goodyear on 20 Sep 23 - No Cached

Group items tagged

Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for No... - 0 views

Manipulating the Immunological Tumor Microenvironment | Frontiers Research Topic - 0 views

Immune suppression and reversal of the suppressive tumor microenvironment | Internation... - 0 views

High and low mutational burden tumors versus immunologically hot and cold tumors and re... - 0 views

Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immun... - 0 views

Understanding the tumor immune microenvironment (TIME) for effective therapy - 0 views

Frontiers | Hyperthermia Targeting the Tumor Microenvironment Facilitates Immune Checkp... - 0 views

Improving immunological tumor microenvironment using electro-hyperthermia followed by d... - 0 views

Frontiers | Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Tu... - 0 views

TGFβ signaling plays a critical role in promoting alternative macrophage acti... - 0 views

The complex role of tumor-infiltrating macrophages | Nature Immunology - 0 views

Frontiers | Hypoxic Characteristic in the Immunosuppressive Microenvironment of Hepatoc... - 0 views

[Full text] The role of regulatory T cells in cancer immunology | ITT - 0 views

Frontiers | Myeloid Derived Suppressor Cells Interactions With Natural Killer Cells and... - 0 views

Frontiers | Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumo... - 0 views

Cancers | Free Full-Text | Mechanisms of Immunosuppression in Colorectal Cancer | HTML - 0 views

NF-κB, an Active Player in Human Cancers | Cancer Immunology Research - 0 views

Improving immunological tumor microenvironment using electro-hyperthermia followed by d... - 0 views

Frontiers | Modulators of the Balance between M1 and M2 Macrophages during Pregnancy | ... - 0 views

Frontiers | Learning from the microbes: exploiting the microbiome to enforce T cell imm... - 0 views

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