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NEW ORLEANS, Nov. 10 -- Gram for gram, trans fatty acid from milk and meat may be as bad for the heart as it is from processed foods, Dutch researchers found. In a randomized trial, a diet containing a high quantity of trans fats significantly increased cholesterol levels across the board whether from natural or "industrial" sources (P=0.014 to P<0.001), Ingeborg A. Brouwer, Ph.D., of VU University Amsterdam, and colleagues reported here at the American Heart Association meeting.

Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review1,3. Hunter JE, Zhang J, Kris-Etherton PM. Am J Clin Nutr. 2009 Nov 25. [Epub ahead of print] PMID: 19939984 doi:10.3945/ajcn.2009.27661 Conclusions: TFA intake should be reduced as much as possible because of its adverse effects on lipids and lipoproteins. The replacement of TFA with STA compared with other saturated fatty acids in foods that require solid fats beneficially affects LDL cholesterol, the primary target for CVD risk reduction; unsaturated fats are preferred for liquid fat applications. Research is needed to evaluate the effects of STA on emerging CVD risk markers such as fibrinogen and to understand the responses in different populations.

Types of dietary fat and risk of coronary heart disease: a critical review. Hu FB, Manson JE, Willett WC. J Am Coll Nutr. 2001 Feb;20(1):5-19. Review. PMID: 11293467