Silver line hospital is one of the super speciality hospital in Kerala, India. The hospital specialising in the treatment of Diabetes, Thyroid, Endocrinology, Obesity, Urology, Dental and Cardiology treatment
A critical review of Vitamin D and cancer: A report of the IARC Working Group on vitamin D
William B. Grant
Dermato-Endocrinology. Volume 1, Issue 1
January/February 2009
Pages: 25 - 33
The International Agency for Research on Cancer (IARC) released a report, Vitamin D and Cancer, on November 25, 2008. The report focused on the current state of knowledge and level of evidence of a causal association between vitamin D status and cancer risk. Although presenting and evaluating evidence for the beneficial role of UVB and vitamin D in reducing the risk of cancer, it discounted or omitted important evidence in support of the efficacy of vitamin D. The report largely dismissed or ignored ecological studies on the grounds that confounding factors might have affected the findings. The report accepted a preventive role of vitamin D in colorectal cancer but not for breast cancer.
"Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology, explores the damage caused by sugary foods. He argues that fructose (too much) and fiber (not enough) appear to be cornerstones of the obesity epidemic through their effects on insulin. Series: UCSF Mini Medical School for the Public [7/2009] [Health and Medicine] [Show ID: 16717] "
Silver Line Hospital provide expert Endocrinologist for the treatment of sexual dysfunction disorder. We offer related treatments like hormone therapy, psychological therapy and diagnosis blood tests, sensory testing, vascular assessment
Silver Line offer treatment for growth abnormalities, abnormal growth of cells, hormone growth deficiency, adult growth hormone deficiency, growth hormone deficiency in children, abnormal bone and tissue growth, endocrine disorders.
Back to the future: a new look at 'old' vitamin D.
Chun RF, Adams JS, Hewison M.
J Endocrinol. 2008 Aug;198(2):261-9. Epub 2008 May 21.
PMID: 18495944
DOI: 10.1677/JOE-08-0170
Reinehr T, de Sousa G, Alexy U, Kersting M, Andler W.
Vitamin D status and parathyroid hormone in obese children before and after weight loss.
Eur J Endocrinol. 2007 Aug;157(2):225-32.
PMID: 17656603 [PubMed - in process]
Sakhaee K, Maalouf NM, Abrams SA, Pak CY.
Effects of potassium alkali and calcium supplementation on bone turnover in postmenopausal women.
J Clin Endocrinol Metab. 2005 Jun;90(6):3528-33. Epub 2005 Mar 8.
PMID: 15755853
Frassetto L, Morris RC Jr, Sebastian A.
Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women.
J Clin Endocrinol Metab. 2005 Feb;90(2):831-4. Epub 2004 Nov 30.
PMID: 15572425 [PubMed - indexed for M
Barger-Lux MJ, Heaney RP. Effects of above average summer sun exposure on serum 25-hydroxyvitamin D and calcium absorption.J Clin Endocrinol Metab. 2002 Nov;87(11):4952-6.PMID: 12414856 [PubMed - indexed for MEDLINE]
Valimaki VV, Alfthan H, Lehmuskallio E, Loyttyniemi E, Sahi T, Stenman UH, Suominen H, Valimaki MJ.
Vitamin D status as a determinant of peak bone mass in young Finnish men.
J Clin Endocrinol Metab. 2004 Jan;89(1):76-80.
PMID: 14715830 [PubMed - indexe
Effect of vitamin D deficiency and replacement on endothelial function in asymptomatic subjects.
Tarcin O, Yavuz DG, Ozben B, Telli A, Velioglu Ogunc A, Yuksel M, Toprak A, Yazici D, Sancak S, Deyneli O, Akalin S.
J Clin Endocrinol Metab. 2009 Jul 7. [Epub ahead of print]
PMID: 19584181
doi:10.1210/jc.2008-1212
Conclusions: This study shows that 25(OH)D deficiency is associated with endothelial dysfunction and increased lipid peroxidation. Replacement of vitamin D has favorable effects on endothelial function. Vitamin D deficiency can be seen as an independent risk factor of atherosclerosis. Hypovitaminosis D associated endothelial dysfunction may predispose to higher cardiovascular disease in the winter.
Vitamin D status predicts physical performance and its decline in older persons.
Wicherts IS, van Schoor NM, Boeke AJ, Visser M, Deeg DJ, Smit J, Knol DL, Lips P.
J Clin Endocrinol Metab. 2007 Jun;92(6):2058-65. Epub 2007 Mar 6.
PMID: 17341569
doi:10.1210/jc.2006-1525
ONCLUSIONS: Serum 25-OHD concentrations below 20 ng/ml are associated with poorer physical performance and a greater decline in physical performance in older men and women. Because almost 50% of the population had serum 25-OHD below 20 ng/ml, public health strategies should be aimed at this group.
The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis.
Pittas AG, Lau J, Hu FB, Dawson-Hughes B.
J Clin Endocrinol Metab. 2007 Jun;92(6):2017-29. Epub 2007 Mar 27. Review.
PMID: 17389701
.CONCLUSIONS: Vitamin D and calcium insufficiency may negatively influence glycemia, whereas combined supplementation with both nutrients may be beneficial in optimizing glucose metabolism.
Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D.
Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, Reitz R, Salameh W, Ameri A, Tannenbaum AD.
J Clin Endocrinol Metab. 2008 Mar;93(3):677-81. Epub 2007 Dec 18.
PMID: 18089691
Conclusion: A 1000 IU dose of vitamin D2 daily was as effective as 1000 IU vitamin D3 in maintaining serum 25-hydroxyvitamin D levels and did not negatively influence serum 25-hydroxyvitamin D3 levels. Therefore, vitamin D2 is equally as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status.
Age-related changes in the 25-hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D.
Vieth R, Ladak Y, Walfish PG.
J Clin Endocrinol Metab. 2003 Jan;88(1):185-91.
PMID: 12519850
This study shows that all age groups exhibit a high prevalence of 25(OH)D insufficiency and secondary hyperparathyroidism. Older adults are just as efficient in maintaining 25(OH)D, but they need more vitamin D to produce the higher 25(OH)D concentrations required to overcome the hyperparathyroidism associated with their diminishing renal function
Comparison of daily, weekly, and monthly vitamin D3 in ethanol dosing protocols for two months in elderly hip fracture patients.
Ish-Shalom S, Segal E, Salganik T, Raz B, Bromberg IL, Vieth R.
J Clin Endocrinol Metab. 2008 Sep;93(9):3430-5. Epub 2008 Jun 10.
PMID: 18544622
doi:10.1210/jc.2008-0241
CONCLUSIONS: Supplementation with vitamin D can be achieved equally well with daily, weekly, or monthly dosing frequencies. Therefore, the choice of dose frequency can be based on whichever approach will optimize an individual's adherence with long-term vitamin D supplementation.