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ryleighnyp

Electrical grounding technique may improve health outcomes of NICU babies -- ScienceDaily - 2 views

www.sciencedaily.com/...170803120627.htm

HSR HSR-2023 potential research idea

shared by ryleighnyp on 07 Jun 23 - No Cached
Sean Nash liked it
  • "What we can conclude is that a baby's autonomic nervous system is able to sense the electrical environment and it seems as though a baby is more relaxed when grounded,"
  • redesigning incubators to ground babies and cancel out the electrical field
  • ryleighnyp on 07 Jun 23
     
    I think a possible research idea could be redesigning NICU incubators to allow for less electromagnet interference with the babies with the use of grounding.
  • Sean Nash on 07 Jun 23
     
    Interesting, for sure. Two things... the actual measurements they made on children (skin tests, etc.) are a no-go for us. I'm not sure what our model system could be for checking the electrical outputs of whatever design changes were made. We would need to know a lot more about the current setup in NICUs. There is no doubt a lot of design in how things are currently set up. Essentially: why things are set up the way they are right now? You would have to know every variable currently considered, and then look for spots where simple changes can be made. Second thing: go back to the ISEF categories in Engineering and check out how those projects look at the national level. Just go get a feel. Engineering is a bit different from typical "hypothesis testing" seen in most natural sciences. Very cool, but different. Give it a look.
katherine-medina

Sci-Hub | A droplet-based electricity generator with high instantaneous power density. ... - 0 views

sci-hub.se/...s41586-020-1985-6

water-power droplets electricity HSR-2023

shared by katherine-medina on 22 Aug 23 - No Cached
    • katherine-medina
      katherine-medina on 22 Aug 23
       
      We find that when a falling water droplet spreads on the PTFE surface, it bridges the originally disconnected components (the PTFE/ITO and aluminum electrode) into a closed-loop, electrical system Interesting.
    • katherine-medina
      katherine-medina on 22 Aug 23
       
      Fig. 1 | Design of the DEG. a, Schematic diagram. b, Optical image showing four parallel DEG devices fabricated on a glass substrate. The volume of each droplet is 100.0 μl. c, As individual droplets continue to impinge on the asfabricated device, the amount of charge on the PTFE surface increases gradually and eventually reaches a stable value. d, One hundred commercial LEDs can be powered when one droplet, released from a height of 15.0 cm, is in contact with the device. e, Under the same experimental conditions (for example, the same droplet size and height of release), the output voltage measured from the DEG (in red, with the frequency of impinging droplets being
  • katherine-medina on 22 Aug 23
     
    Interesting to see a different method on creating power out of water. I kinda of want to look into the science of water.
Sean Nash

Learning in Plants: Lessons from Mimosa pudica - 4 views

www.frontiersin.org/...full

Mimosa learning plants botany research SCI-I science student lab potential research idea biology HSR HSR-2023

shared by Sean Nash on 23 Jun 23 - No Cached
  • there is a lack of observational data on the behavior of plants
  • Observational research allows the researcher to establish baseline activity and response levels of the subject
  • Perhaps the first study of learning in plants was a habituation experiment reported by Pfeffer (1873) using the sensitive plant Mimosa. In this experiment, repeated mechanical stimulation of leaflets led to a decrease in sensitivity
  • ...12 more annotations...
  • the question naturally arises as to whether Mimosa can discriminate between stimuli. This was answered in the affirmative by Holmes and Gruenberg (1965) whose experimental design included a drop of water and finger touch as stimuli
  • the results suggest that Mimosa can discriminate between stimuli
  • Thomas performed an experiment on classical conditioning in Mimosa that took advantage of the finding that, under field conditions, the leaflets of Mimosa slowly drop as dusk approaches and slowly rise at dawn (personal communication). In the experiment, the CS was turning on the light in the growth chamber and the US was touching selected leaflets. Thomas found that leaflets in the paired condition showed conditioning compared to a light only or alternating stimulation condition. This finding should be replicated with controls for pseudoconditioning.
  • Given the importance of the Gagliano et al. (2014) experiment and the failure to replicate some previous experimental results it is critical that the Gagliano et al. (2014) results be repeated by an independent laboratory.
  • In addition to Mimosa, habituation has been found in the carnivorous plant Drosera (sundew
  • Applewhite (1975) cites an experiment by Darwin reportedly showing habituation in the passion flower (Passiflora gracilis). During this experiment, when Darwin mechanically stimulated the passion flower tendrils, the tendrils no longer responded after 54 h of training.
  • Abramson et al. (2002) investigated the use of bioelectrical potentials as a method to explore plant behavior.
  • In an interesting article, Karpinski and Szechynska-Hebda (2010) discuss the intellect of plants from memory to intelligence. By studying recall, the researcher investigates a host of independent variables and that are solidly anchored to a set of dependent variables. This study focused on recall at the cellular level rather than as an externally observable behavior. The discussion of plant learning at various levels, from cellular to organismal and from different scientific fields is exactly what is advocated for in this article
  • There is also interest from behavioral scientists seeking to determine whether the similarities and differences in learning found among invertebrates and vertebrates could also be found in plants (Warden et al., 1940; Applewhite, 1975; Abramson et al., 2002; Guiguet, 2013).
  • The majority of early plant studies used the Sensitive plant (M. pudica). Mimosa has much to recommend it for learning studies. They are easy to maintain, much is known about its natural history, and they have a visible leaf closure response to external stimuli. However, there are drawbacks in the use of Mimosa, for example, it takes about 15 min for a leaf to recover (Holmes and Gruenberg, 1965) and not much is known about its genome in contrast to model species such as Arabidopsis thaliana whose entire genome is known.
  • In the following section we will focus on methods to develop studies utilizing habituation, sensitization, and classical conditioning techniques. Instrumental and operant conditioning will not be covered because at this time there are no Mimosa studies in these areas; although one can envision a situation where the opening and closing of a leaf can be detected electronically. Once detected, the response would produce a consequence such as an airpuff or changes in light intensity.
    • Sean Nash
      Sean Nash on 23 Jun 23
       
      The remainder of this comprehensive article is to outline the main lines of research in this area:
  • Learning in Plants: Lessons from Mimosa pudica
    • Sean Nash
      Sean Nash on 23 Jun 23
       
      This well-compiled article does a really nice job of outlining the history of study regarding plant behavior. It also suggests model organisms for study. Mimosa is a favorite of mine as their response is VERY rapid and quite visible for a plant! There are all sorts of feasible project ideas that could arise from this area of research.
katherine-medina

A virus of hyperthermophilic archaea with a unique architecture among DNA viruses | PNAS - 0 views

www.pnas.org/...pnas.1518929113

bacteria HSR-2023 environmental hot-spring

shared by katherine-medina on 24 May 23 - No Cached
  • ssDNA, ssRNA, and ds
  • One of these isolates was subjected to an additional round of colony purification, and the isolated strain, designated “2GA,” was selected as a standard virus host for all following experiments, unless stated otherwise.
  • Cells of the 2GA isolate are rod-shaped, with an average length of about 4 μm and a width of about 0.7 μm.
  • ...1 more annotation...
  • A combination
ryleighnyp

BMED010 - Natural and Commercial Moisturizers on Skin Model | Regeneron ISEF 2023 - 2 views

projectboard.world/...ial-moisturizers-on-skin-model

ISEF fair project

shared by ryleighnyp on 23 May 23 - No Cached
  • ryleighnyp on 23 May 23
     
    This is a good example of data collection, experimental design, and presentation.
Sean Nash

Shining the Light on Baby Crabs | Hakai Magazine - 2 views

hakaimagazine.com/...hining-the-light-on-baby-crabs

methods inexpensive SCI-I HSR HSR2023 research invertebrates zoology crabs dungeness Canada PugetSound Vancouver light potential research idea biology environmental science HSR-2023

shared by Sean Nash on 30 Apr 23 - No Cached
  • Sean Nash on 30 Apr 23
     
    I added this one, which includes detail of an environmental study, to illustrate how creative use of everyday materials can sometimes work to design scientific methods that work!
katherine-medina

Sci-Hub | Amyloid-β as a Blood Biomarker for Alzheimer's Disease: A Review of... - 0 views

sci-hub.ru/...31868667

blood-plasma biomarkers Alzheimer's-disease potential research idea HSR-2023

shared by katherine-medina on 31 May 23 - No Cached
    • katherine-medina
      katherine-medina on 31 May 23
       
      So seeing as if scientists have mostly studied AB40-42, and 38 why don't they look at the other peptides under the name of AB.
    • katherine-medina
      katherine-medina on 31 May 23
       
      I shall take note of this excerpt of the passage for future reference, "The discrep- 104 ancy between these two ultrasensitive assays may 105 be due to the different principle and design that 106 IMR assay could inhibit the oligomerization of A42 107 by the iron-chelating effect of magnetic Fe3O4 108 nanoparticles."
    • katherine-medina
      katherine-medina on 31 May 23
       
      Important to see that they are figuring out that, "that there is a blood-brain transportation mechanism 261 for A and indicated that plasma A may be able to 262 reflect the brain A condition."
  • ...1 more annotation...
    • katherine-medina
      katherine-medina on 31 May 23
       
      Maybe I could look into the blood plasma levels AB1-40 and make it into a sort of predictor that could show if somehow may in future years live with some sort of Alzeheimer's Dementia.
  • katherine-medina on 31 May 23
     
    A good look at what scientist have found about the presence of Amyloid B in the blood as a biomarker for Alzheimer's disease
katherine-medina

Increased 3-O-sulfated heparan sulfate in Alzheimer's disease brain is associated with ... - 1 views

www.science.org/...sciadv.adf6232

Alzheimer's-disease Research-idea brain HSR-2023 Human

shared by katherine-medina on 27 May 23 - No Cached
  • Genetic factors contribute substantially to the pathological process of AD as demonstrated by the fact that the genetic heritability in AD is in the range of between 60 and 80% (10).
  • however, whether the variants alter the level of 3-OST-1 enzyme activity to change the structure of HS remains unknown
    • katherine-medina
      katherine-medina on 27 May 23
       
      Good to note what exactly the article remains unsure about
  • The synthesis of additional 13C-labeled calibrants to cover these three reported 3-O-sulfated tetrasaccharides will be the subject for future study.
    • katherine-medina
      katherine-medina on 27 May 23
       
      LOOK INTO THIS PART CAYSE THEY ARE SAYING THAT THEY ARE NOT FULLY SURE
  • ...4 more annotations...
  • the elevation of total HS and the percentage of the 3-O-sulfated domain in HS.
  • HS and tau revealed that the sugar mainly interacts with the proline-rich region 2, a repeat domain 2 in tau protein
  • Further analysis of the distribution of 3-O-sulfated HS from different areas of AD brains will be of interest and the subject for a subsequent study.
  • Experimental design
    • katherine-medina
      katherine-medina on 27 May 23
       
      READ THIS IF THIS TOPIC COMES BACK UP AGAIN
  • katherine-medina on 27 May 23
     
    A interesting study about a sulfate that suggests that Alzheimer's is genetic
Xander Kleiber

Energy-efficient computing | MIT Energy Initiative - 2 views

energy.mit.edu/...energy-efficient-computing

potential research idea computer science engineering HSR HSR-2023

shared by Xander Kleiber on 05 Jun 23 - No Cached
Sean Nash liked it
  • 1’s are literally thrown away, and that wasted energy is dissipated as heat.
    • Xander Kleiber
      Xander Kleiber on 05 Jun 23
       
      In logic gates specifically, because there are cases where a 1 goes in and a 0 can come out, that 1 (directly represented by electrical voltage) gets wasted in the computation and is released as heat.
  • the inputs are 1-0 and 0-1, and the output is 1-0. That setup is wasteful: An incoming 1 is lost during the computation. The researchers solve that problem by retaining the extra inputs as “garbage bits” that carry useless information (see the bottom example). The 1-0 order doesn’t matter, but now the number of 1’s is preserved after the computation.
    • Xander Kleiber
      Xander Kleiber on 05 Jun 23
       
      Seems like a great way to solve the issue. However, I don't see anywhere else in the article any sort of actual circuit design/implementation of said solution...
  • On the energy front, the goal is to conserve all information—not just the 1’s but the 0’s as well. Their approach is based on “reversible computing,” an idea first proposed in the 1970s.
    • Xander Kleiber
      Xander Kleiber on 05 Jun 23
       
      Expanded upon later.
  • ...1 more annotation...
  • “If you can play everything backwards, then no energy has escaped during your computation,” says Demaine.
    • Xander Kleiber
      Xander Kleiber on 05 Jun 23
       
      So in reversible computing, if an algorithm can be reversed, that means no information (and therefore no 1's, or measures of voltage) are wasted, resulting in an even lower production of waste.
  • Xander Kleiber on 05 Jun 23
     
    Overall, this seems like a decent course of study. After all, mentioned throughout the article is something called "Landauer's limit," which is a limit to the efficiency of computing devices using the current, wasteful methods. Also mentioned briefly in the article is that we are continually getting much closer to this limit. This makes it a timely issue, along with the fact that not many people have elaborated on its implications or tried implementing it.
  • Sean Nash on 06 Jun 23
     
    This is really interesting... though I'm sure I would benefit from a back-and-forth conversation to make sure I'm understanding what I think I am.
Sean Nash

How patient-led research could speed up medical innovation - 0 views

www.sciencenews.org/...t-led-research-health-medicine

design engineering medical biomedical research HSR-2023 HSR potential research idea biology statistical analysis questions science

shared by Sean Nash on 04 Apr 24 - No Cached
  • Sean Nash on 04 Apr 24
     
    This makes me think of my Mom and her struggle with migranes. She would benefit from a simple iOS app that helps her track symptoms & potential triggers in a way that could easily be shared with her doctor.
Sean Nash

Airplane Noise Exposure May Increase Risk of Chronic Disease | SPH - 0 views

www.bu.edu/...crease-risk-of-chronic-disease

HSR HSR-2025 airplane noise disease environmental science questions statistical analysis mathematics computer science potential research idea behavioralscience

shared by Sean Nash on 06 Jun 24 - No Cached
  • “Prior research has shown that aircraft noise can elevate stress responses and disturb sleep, but there has been mixed evidence of any links with body mass index,” says study lead and corresponding author Matthew Bozigar, assistant professor of epidemiology at OSU and a former postdoctoral associate at SPH. “We were surprised to see a fairly robust link between aircraft noise and higher body mass index among women across the US.”
    • Sean Nash
      Sean Nash on 06 Jun 24
       
      Again, this reminds me of the UCSD juncos and the increased stressors they must endure to live in an urban environment. However, we must remember that just because their emerging population in and around the UCSD campus is successful, it comes with a cost of shorter lifespans, increased mortality, etc. Very interesting stuff.
  • These new findings underscore the role of the environment on one’s risk of chronic disease.
  • Junenette Peters, associate professor of environmental health, and colleagues examined airplane noise exposure and self-reported BMI and other individual characteristics among nearly 75,000 participants living around 90 of the major US airports
  • ...5 more annotations...
  • The team examined aircraft noise levels every five years from 1995 to 2010, using a day-night estimate (DNL) that captures the average noise level over a 24-hour period and applies a 10 dB adjustment for aircraft noise occurring at night, when background noise is low.
  • Although the team acknowledges that BMI is a suboptimal metric, the independent and strong association between more aircraft noise exposure and higher BMI that they observed is notable.
  • “We can only hypothesize about why we saw these regional variations, but one reason may relate to the era of regional development, building characteristics, and climate which may affect factors such as housing age, design, and level of insulation,” says Peters. “Regional differences in temperature and humidity may influence behaviors such as window opening, so perhaps study participants living in the West were more exposed to aircraft noise due to open windows or housing type, which allowed more noise to penetrate.”
  • Previous data suggest that Black, Hispanic, and low-income populations are disproportionately exposed to aircraft noise. The participants in the NHS study groups were primarily White and of mid-level socioeconomic status. 
  • “We need to study the potential health impacts of environmental injustices in transportation noise exposures alongside other environmental drivers of poor health outcomes” Bozigar says. “There is a lot more to figure out, but this study adds evidence to a growing body of literature that noise negatively impacts health.”
Sean Nash

Race car drivers tend to blink at the same places in each lap - 4 views

www.sciencenews.org/...ula-one-race-car-drivers-blink

ArduinoScienceJournal app driving blinking vision research potential research idea biology engineering HSR HSR-2023 science statistical analysis car auto safety civilengineering blink

shared by Sean Nash on 25 May 23 - No Cached
izzy kelly liked it
  • The world goes dark for about one-fifth of a second every time you blink, a fraction of an instant that’s hardly noticeable to most people. But for a Formula One race car driver traveling up to 354 kilometers per hour, that one-fifth means almost 20 meters of lost vision
  • People are often thought to blink at random intervals, but researchers found that wasn’t the case for three Formula drivers.
  • the drivers tended to blink at the same parts of the course during each lap, cognitive neuroscientist Ryota Nishizono and colleagues report in the May 19 iScience
    • Sean Nash
      Sean Nash on 25 May 23
       
      Interesting. So, do we do the same thing while driving around town? Could you design a method to record eye blinks as people drive known routes around town? We could simultaneously use the Arduino Science Journal app on the iPhone to also correlate physical data in a moving car like acceleration/deceleration, motion in X, Y, Z directions, etc. I wonder if we could find a correlation in everyday driving that could help from a safety perspective?
  • ...5 more annotations...
  • He was surprised to find almost no literature on blinking behavior in active humans even though under extreme conditions like motor racing or cycling
    • Sean Nash
      Sean Nash on 25 May 23
       
      OK, now this SCREAMS: "potential research idea."
  • Nishizono and colleagues mounted eye trackers on the helmets of three drivers and had them drive three Formula circuits
  • Where the drivers blinked was surprisingly predictable, the team found. The drivers had a shared pattern of blinking that had a strong connection with acceleration, such that drivers tended not to blink while changing speed or direction — like while on a curve in the track — but did blink while on relatively safer straightaways.
    • Sean Nash
      Sean Nash on 25 May 23
       
      What sort of implications does this have for driving in key, known, busy interchanges in KC? Could we potentially provide data to show certain stretches of highway need more signage, etc? That could have civil engineering implications.
  • “We think of blinking as this nothing behavior,” he says, “but it’s not just wiping the eyes. Blinking is a part of our visual system.”
  • Nishizono next wants to explore what processes in the brain allow or inhibit blinking in a given moment, he says, and is also interested in how blinking behavior varies among the general population.
    • Sean Nash
      Sean Nash on 25 May 23
       
      While the "brain" part might move beyond our feasibility, the potential of finding real correlations to driving patterns or routes is a completely different spin-off and one that could have really practical suggestive applications for city planners, etc.
Sean Nash

Mysterious Underwater Acoustic World of British Ponds Revealed in New Study | Current S... - 3 views

currentsciencedaily.com/...sh-ponds-revealed-in-new-study

hydrophone sound survey pond potential research idea biology physics computer science environmental science HSR HSR-2023

shared by Sean Nash on 04 Jun 23 - No Cached
  • The previously hidden and diverse underwater acoustic world in British ponds has been revealed by a team of researchers at the University of Bristol.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      So... my immediate thought is: How cool would it be to do this here? One thing we DO have: PONDS. See if this *sounds* interesting. Get it? ;)
  • Acoustic monitoring has been shown to effectively survey birds and monkeys in rainforests, and marine mammals in the oceans. However, freshwater environments have remained largely unexplored despite their diverse soundscapes.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      BOOM. Again, "relatively unexplored" is super exciting verbiage to me. Acoustics. Hydrophones. Is this feasible? Is the equipment affordable? If not, could we borrow one? Dig into it. What are the possibilities?
  • analysis of the audio files revealed clear daily acoustic activity cycles in each pond
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      Aside from the exploratory surveys you would do just to see "what's out there" and assess what we CAN learn from listening to a pond, you could make it experimental by comparing ponds you've assessed the health of by other means. In other words, do acoustic comparisons between two ponds correlate with what you find by doing a macroinvertebrate sampling? I really LIKE the possibilities in this one!
  • ...3 more annotations...
  • Typically, a nocturnal chorus is made by aquatic insects that compete to attract mates by producing strange scratching sounds as they rub their genitals against their abdomens. During the daytime, however, aquatic plants dominate the underwater orchestra with rhythmic whining and ticking sounds produced as tiny oxygen bubbles are released by plants respiring in the hot sun.
  • Using this acoustic method, the presence of species, and a determination of ecological health, can be inferred simply by listening to the natural world without disturbing the environment or harming the plants and animals within it.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      Here is the obvious value proposition if you could work this out.
  • Publication: Jack A. Greenhalgh, et al., Diel variation in insect-dominated temperate pond soundscapes and guidelines for survey design, Freshwater Biology (2023). DOI: 10.1111/fwb.14092.
    • Sean Nash
      Sean Nash on 04 Jun 23
       
      BEST THING YET: Here is the FULL TEXT of the actual research paper!
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