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China: Reports of bird flu in humans reach 60 - CNN.com - 1 views

www.cnn.com/...china-bird-flu flu humans virus
shared by Whitney Hopfauf on 15 Apr 13 - No Cached
  • Whitney Hopfauf on 15 Apr 13
     
    This is so scary. I am always wary when China says, "Don't worry everything is under control". China was criticized during the SARS outbreak for failing to release information. If bird flu ever gains the ability to spread from human to human, we have a very bad situation.
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Scientists Use Nature Against Nature to Develop an Antibiotic With Reduced Resistance - 0 views

www.sciencedaily.com/...130410201828.htm microbiology resistance antibiotic
shared by Megan Rasmussen on 14 Apr 13 - No Cached
  • Megan Rasmussen on 14 Apr 13
     
    Researchers have applied knowledge about bacteria phages in order to develop a new antibiotic. They studied the enzyme 2-epimerase, which controls the formation Bacillus anthracis cell wall. Researchers used an inhibitory molecule that would bind to the allosteric site* site of this enzyme. They tested this antibiotic called Epimerox in mice infected with Ballcillus anthracis and found that it protected the mice from anthrax. It also showed that the bacteria did not develop a resistance to this inhibitory molecule. Although this is just a start, it could change so much in the quest for effective antibiotics!
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Secrets of bacterial slime revealed - 1 views

www.sciencedaily.com/...130412132413.htm
shared by Katelyn Madigan on 13 Apr 13 - No Cached
  • help identify a new target for antibiotics and prevent other biofilms from forming
  • regulator of biofilm formation, a protein called SinR, acts in the model bacterium, Bacillus subtilis.
  • Katelyn Madigan on 13 Apr 13
     
    While this still seems like a somewhat preliminary study on protein interactions, I think this is an important direction for future studies due to the increased understanding of the dangers of biofilms.
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Good parenting vs. effective parenting on imgfave - 2 views

imgfave.com/3392161
shared by Tiffany Arcand on 13 Apr 13 - No Cached
  • Tiffany Arcand on 13 Apr 13
     
    This is not scientific nor do I expect it to count towards my 10 articles, I just found it humorous and thought I would share :]
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Clinging to crevices, E. coli thrive: Study reveals role of flagellum in helping biofil... - 1 views

phys.org/...li-reveals-role-flagellum.html
shared by Amy Jorgenson on 11 Apr 13 - No Cached
  • Amy Jorgenson on 11 Apr 13
     
    How big of a part do you think this finding plays in the rise of biofilm formations?
  • Casey Finnerty on 11 Apr 13
     
    Well, I think this result will pop the balloon of enthusiasm many had for new nanotechnologies that were supposed to prevent colonization/biofilm formation. #$%&! E. coli!
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New Technologies in Clinical Microbiology - 0 views

jcm.asm.org/...S62.full clinical microbiology
shared by Casey Finnerty on 11 Apr 13 - No Cached
  • Unfortunately, when laboratory methods rely solely on cultivation of pathogens and traditional phenotypic methods of pathogen characterization, physicians are forced to deduce the presence of BSI based on clinical symptoms, which are often nonspecific. Subsequently, antibiotic therapy is initiated based on clinical and epidemiologic profiles (28) rather than on laboratory evidence. Typically, within 1 to 3 days a microscopic Gram stain category (Gram-positive bacteria, Gram-negative bacteria, or fungi) provides physicians with a general direction for antibiotic therapy. Definitive results that eliminate the need for broad-spectrum therapy and enable de-escalation and the tailoring of treatment to the most effective antibiotic regimen often require more than 3 to 5 days. This gap has been implicated as one reason for high mortality and the emergence of drug-resistant microbes.
    • Casey Finnerty
      Casey Finnerty on 11 Apr 13
       
      Alison, I found this reference after our chat today at the end of the lab. I think you would find this paper very interesting.
  • Casey Finnerty on 11 Apr 13
     
    This paper is an excellent review on the need for improved protocols for microbial identification the technologies that are under development.
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Lyme disease vaccine? Tick saliva found to protect mice from Lyme disease - 0 views

www.sciencedaily.com/...091119111410.htm lyme vaccine microbiology
shared by Whitney Hopfauf on 11 Apr 13 - No Cached
  • antibodies against a protein in the saliva of a pathogen's transmitting agent
  • has been shown to confer immunity when administered protectively as a vaccine.
  • Lyme bacterium known as
  • ...6 more annotations...
  • Borrelia burgdorferi
  • . When it moves through the tick, it is coated with a tick salivary protein known as Salp15
  • injected Salp15 into healthy mice and found that it significantly protected them from getting Lyme disease
  • combined with outer surface proteins of B. burgdorferi, the protection was even greater.
  • Lyme vaccine on the market that utilized just the outer surface proteins of the bacteria. It was taken off the market in 2002
  • targeting the saliva -- the "vector molecule" that a microbe requires to infect a host -- may be applicable not just to Lyme disease but to other insect-borne pathogens
  • Whitney Hopfauf on 11 Apr 13
     
    This is slightly out of date but very interesting
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Bugs As Drugs - Phenomena: The Loom - 1 views

phenomena.nationalgeographic.com/...bugs-as-drugs microbiology microbiome
shared by Casey Finnerty on 10 Apr 13 - No Cached
  • “In 15 years, we will all be drinking specific, personalized probiotic cocktails. I suggest that every healthy person freezes a fecal sample now so they will be able to treat themselves in the future.”
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Avian virus may be harmful to cancer cells - 0 views

www.sciencedaily.com/...130408142644.htm virus cancer
shared by Tyrell Varner on 09 Apr 13 - No Cached
  • We modified the virus so that it replicates only in the presence of an active prostate-specific antigen and, therefore, is highly specific to prostate cancer. We also tested its efficacy in a tumor model in vitro," Subbiah said. "The recombinant virus efficiently and specifically killed prostate cancer cells, while sparing normal human cells in the laboratory, but it would take time for this to move from the discovery phase to a treatment for prostate cancer patients."
  • Tyrell Varner on 09 Apr 13
     
    They are looking for commercial entities that are interested in licensing the technology for human clinical trials and treatment. In addition, the researchers have also received a National Institutes of Health exploratory grant to develop the cell type-specific disease virus for several other types of cancer cells, including breast, pancreas, brain, prostate, and multiple myeloma. Although, it will work most effectively in prostate cancer.
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Bathing, but Not Alone - NYTimes.com - 0 views

www.nytimes.com/...15shower.html
shared by Alison Prodzinski on 08 Apr 13 - No Cached
  • Another paradox of city life: it seems it is healthier to inhale the subway’s air than the shower’s mist.
  • the deluge of bacteria that hit your face and flow deep into your lungs in the morning shower
  • Running the water for 30 seconds before stepping in would mean fewer bacteria in one’s face
  • ...3 more annotations...
  • Aside from the thought of being sprayed in the face by a bacterial cocktail every morning, the shower bacteria present no serious danger
  • the subway air is remarkably fresh and like outdoor air
  • Another paradox of city life: it seems it is healthier to inhale the subway’s air than the shower’s mist.
  • Alison Prodzinski on 08 Apr 13
     
    Bacteria are everywhere - including the shower!! There are 15 different kinds of bacteria that live in the shower -- they get into your lungs via inhalation and your skin. These bacteria are not all bad though - only Mycobacterium avium - it can cause chest complaints and issues. Research on the shower and bacteria was then compared to a New York City subway - in which the subway was healthier then the shower! WOW!! However, hope is not lost - researchers said to run the shower for 30 seconds and most bacteria will be gone!!
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Skin deep: Fruit flies reveal clues to wound healing in humans - 0 views

www.sciencedaily.com/...130405094515.htm antibiotic wounds
shared by Tyrell Varner on 08 Apr 13 - No Cached
  • Tyrell Varner on 08 Apr 13
     
    The possibility of modeling fruit flies for wound healing is mind blowing. Fruit flies were used since their genetics are not as complicated as mammals. However their exterior defense is quite similar to mammals.
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U.S. Considers Testing A Vaccine Against Weaponized Anthrax For Children | Popular Science - 1 views

www.popsci.com/...-test-anthrax-vaccine-children
shared by Jeremiah Williamson on 08 Apr 13 - No Cached
  • Jeremiah Williamson on 08 Apr 13
     
    Bioterrorism is a scary thought, but is the government going too far?  A vaccine against anthrax may be a bit much, especially testing it on children.
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These Are The World's Deadliest Killers | Popular Science - 0 views

www.popsci.com/...e-are-worlds-deadliest-killers
shared by Jeremiah Williamson on 08 Apr 13 - No Cached
  • Jeremiah Williamson on 08 Apr 13
     
    Using this new microscope resolution power, doctors may finally be able to deliver drugs to effectively defeat some of the deadliest pathogens.
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New Method Developed To Kill Pathogenic Bacteria Without Antiobiotics Or Chemicals - 0 views

www.medicalnewstoday.com/...258549.php
shared by Abdirizak Abdi on 05 Apr 13 - No Cached
  • Abdirizak Abdi on 05 Apr 13
     
    Researchers have developed a new method to eliminate deadly pathogenic bacteria in food products and packaging, without the need for antibiotics or chemicals. The method can kill various types of pathogenic bacteria, including Listeria, which is among most common cause of food-borne illness. The team of engineers managed to successfully attach cell lytic enzymes to silica nano particles, which are entirely safe to be used with food products, and created a coating that could selectively kill Listeria, when it gets contact with the bacteria, without affecting other chemicals or bacteria present. The process takes few mins and can tackle listeria even in high concentration.The lytic enzymes could be attached to starch nanoparticles that are typically used for food packaging.
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Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders? - 1 views

www.hindawi.com/...879151
shared by Katelyn Madigan on 04 Apr 13 - No Cached
  • gut microbiota differs at the phylum level depending on weight status
  • human obesity is associated with a low abundance of intestinal Bacteroidetes and high abundance of Firmicutes
  • The mere presence of gut microbiota has recently been shown to contribute to obesity
  • Katelyn Madigan on 04 Apr 13
     
    With the further studies in ratios of gut microbes found in people of varying weights, there are different treatments also being performed on people that undergo bypass surgery to alter the gut microbes to sustain weight loss.
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Rory Staunton: Boy, 12, dies after 'doctors fail to spot infection ravaging his body' |... - 0 views

www.dailymail.co.uk/...t-infection-ravaging-body.html boy dies
shared by Katelyn Madigan on 04 Apr 13 - No Cached
  • Katelyn Madigan on 04 Apr 13
     
    This is the shocking article that was talked about during class. This just shows how we all have to take these warning signs seriously and realize there are risks with exposure in every day incidents.
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Recollections of Charlie: Dr. Charles Alderson Janeway, Jr. (1943-2003) - 0 views

www.ncbi.nlm.nih.gov/...PMC2193774 vaccination immune
shared by Whitney Hopfauf on 04 Apr 13 - No Cached
  • Whitney Hopfauf on 04 Apr 13
     
    Immunology's Dirty Little Secret
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Severe Food Allergy Stresses Moms, Baffles Doctors - Yahoo! - 1 views

gma.yahoo.com/71904938--abc-news-health.html
shared by Jeremiah Williamson on 03 Apr 13 - No Cached
  • Jeremiah Williamson on 03 Apr 13
     
    Going along with the immunology portion of class, this article talks about a new food allergy that a little boy suffers.  He is allergic to almost all food, except a handful of things.  it causes an immune response that is non-IgE, which is the case in most allergies.  
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