Contents contributed and discussions participated by Katelyn Madigan - WSU BIOL209 Microbiology

Potential novel treatment for influenza discovered: Scientists pursue new therapies as ... - 0 views

www.sciencedaily.com/...130501154440.htm

shared by Katelyn Madigan on 02 May 13 - No Cached

latest deadly strain of flu, H7N9, is spreading in China -- 82 people in China had been infected with the new strain of flu virus as of April 26, and 17 had died.
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result of an immune reaction mediated by a protein called Toll-like receptor 4 (TLR4).
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Currently, vaccines and antiviral medications are the two main approaches to preventing influenza
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Katelyn Madigan on 02 May 13

I thought it was interesting that antiviral medications should be administered within two days of infection in order to be effective. This really outlines the need for more effective treatments since this is a very short time frame and there is an increasing resistance to these antiviral therapies in general.

<div class="cArrow"> </div><div class="cContentInner">I thought it was interesting that antiviral medications should be administered within two days of infection in order to be effective. This really outlines the need for more effective treatments since this is a very short time frame and there is an increasing resistance to these antiviral therapies in general.</div>

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ScienceDirect.com - Journal of Allergy and Clinical Immunology - The proteome of Toll-l... - 0 views

www.sciencedirect.com/...S0091674913000857

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Katelyn Madigan on 01 May 13

Supplementary paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplementary paper for presentation.</div>

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ScienceDirect.com - Immunity - Human TRAF3 Adaptor Molecule Deficiency Leads to Impaire... - 0 views

www.sciencedirect.com/...S1074761310003195

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Katelyn Madigan on 30 Apr 13

Supplemental paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper for presentation.</div>

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The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic... - 0 views

www.jimmunol.org/...5260.short

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Katelyn Madigan on 30 Apr 13

Supplemental paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper for presentation.</div>

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ScienceDirect.com - Trends in Immunology - Astrocytes are active players in cerebral in... - 0 views

www.sciencedirect.com/...S1471490607000245

shared by Katelyn Madigan on 30 Apr 13 - No Cached

Katelyn Madigan on 30 Apr 13

Supplemental paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper for presentation.</div>

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Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal ence... - 0 views

www.ncbi.nlm.nih.gov/...PMC337050

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Katelyn Madigan on 30 Apr 13

Focus paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Focus paper for presentation. </div>

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Acyclovir. An updated review of its antiviral activity... [Drugs. 1989] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...2653790

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Katelyn Madigan on 30 Apr 13

Supplemental paper discussing the mechanism of action for acyclovir, an antiviral treatment for Herpes simplex virus encephalitis (HSE).

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper discussing the mechanism of action for acyclovir, an antiviral treatment for Herpes simplex virus encephalitis (HSE). </div>

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Diagnosis and treatment of viral encephalitis -- Chaudhuri and Kennedy 78 (924): 575 --... - 0 views

pmj.bmj.com/...575.sho

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Katelyn Madigan on 30 Apr 13

Supplemental paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper for presentation. </div>

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JSTOR: The Journal of Infectious Diseases, Vol. 155, No. 3 (Mar., 1987), pp. 359-364 - 0 views

www.jstor.org/...30105045

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Katelyn Madigan on 30 Apr 13

Supplemental paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper for presentation. </div>

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ScienceDirect.com - The Lancet - Viral encephalitis: familiar infections and emerging p... - 0 views

www.sciencedirect.com/...S014067360207681X

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Katelyn Madigan on 30 Apr 13

Supplemental paper for presentation.

<div class="cArrow"> </div><div class="cContentInner">Supplemental paper for presentation. </div>

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VIRAL ENCEPHALITIS: CAUSES, DIFFERENTIAL DIAGNOSIS, AND MANAGEMENT -- Kennedy 75 (suppl... - 0 views

jnnp.bmj.com/...i10.sho

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Katelyn Madigan on 30 Apr 13

Focus paper for presentation.

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Discovery of wound-healing genes in flies could mitigate human skin ailments - 0 views

www.sciencedaily.com/...130424185203.htm

shared by Katelyn Madigan on 25 Apr 13 - No Cached

key to their technique was the use of trypsin, a member of a family of enzymes called serine proteases, which activates genes involved in wound healing
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incorporating specific, regulated series proteases and antimicrobial peptides at the sites of diabetic ulcers or skin grafts for more efficient wound healing
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Katelyn Madigan on 25 Apr 13

A specific approach to target the genes that are involved in wound healing seems like a progressive approach for several skin disorders.

<div class="cArrow"> </div><div class="cContentInner">A specific approach to target the genes that are involved in wound healing seems like a progressive approach for several skin disorders. </div>

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Secrets of bacterial slime revealed - 1 views

www.sciencedaily.com/...130412132413.htm

shared by Katelyn Madigan on 13 Apr 13 - No Cached

help identify a new target for antibiotics and prevent other biofilms from forming
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regulator of biofilm formation, a protein called SinR, acts in the model bacterium, Bacillus subtilis.
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Katelyn Madigan on 13 Apr 13

While this still seems like a somewhat preliminary study on protein interactions, I think this is an important direction for future studies due to the increased understanding of the dangers of biofilms.

<div class="cArrow"> </div><div class="cContentInner">While this still seems like a somewhat preliminary study on protein interactions, I think this is an important direction for future studies due to the increased understanding of the dangers of biofilms. </div>

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Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders? - 1 views

www.hindawi.com/...879151

shared by Katelyn Madigan on 04 Apr 13 - No Cached

gut microbiota differs at the phylum level depending on weight status
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human obesity is associated with a low abundance of intestinal Bacteroidetes and high abundance of Firmicutes
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The mere presence of gut microbiota has recently been shown to contribute to obesity
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Katelyn Madigan on 04 Apr 13

With the further studies in ratios of gut microbes found in people of varying weights, there are different treatments also being performed on people that undergo bypass surgery to alter the gut microbes to sustain weight loss.

<div class="cArrow"> </div><div class="cContentInner">With the further studies in ratios of gut microbes found in people of varying weights, there are different treatments also being performed on people that undergo bypass surgery to alter the gut microbes to sustain weight loss. </div>

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Rory Staunton: Boy, 12, dies after 'doctors fail to spot infection ravaging his body' |... - 0 views

www.dailymail.co.uk/...t-infection-ravaging-body.html

boy dies

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Katelyn Madigan on 04 Apr 13

This is the shocking article that was talked about during class. This just shows how we all have to take these warning signs seriously and realize there are risks with exposure in every day incidents.

<div class="cArrow"> </div><div class="cContentInner">This is the shocking article that was talked about during class. This just shows how we all have to take these warning signs seriously and realize there are risks with exposure in every day incidents. </div>

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When hungry, Gulf of Mexico algae go toxic - 0 views

www.sciencedaily.com/...130312171620.htm

algae toxic

shared by Katelyn Madigan on 13 Mar 13 - No Cached

Karenia brevis algae, which cause red tide blooms across the Gulf of Mexico, become two to seven times more toxic when levels of phosphorus, a major algal nutrient found in fertilizers and human waste, are low.
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excess nutrients like phosphorus and nitrogen play key roles in fueling algal growth and harmful algal bloom development.
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Nanoparticles loaded with bee venom kill HIV - 0 views

www.sciencedaily.com/...130307160325.htm

bee venom hiv virus

shared by Katelyn Madigan on 08 Mar 13 - No Cached

ee venom contains a potent toxin called melittin that can poke holes in the protective envelope that surrounds HIV
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When the nanoparticles come into contact with normal cells, which are much larger in size, the particles simply bounce off
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an advantage of this approach is that the nanoparticle attacks an essential part of the virus' structure. In contrast, most anti-HIV drugs inhibit the virus's ability to replicate
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...1 more annotation...
The nanoparticles could be injected intravenously and, in theory, would be able to clear HIV from the blood stream
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First documented case of child cured of HIV - 0 views

www.sciencedaily.com/...130303172640.htm

microbiology immune HIV child

shared by Katelyn Madigan on 04 Mar 13 - No Cached

i diagnosed with HIV at birth and immediately put on antiretroviral therapy.
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brought back into care at 23 months, despite being off treatment for five months, the child was found to have an undetectable viral load
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d today no signs of HIV infection in the child can be detected by the most sensitive means available.
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...2 more annotations...
physician was able to treat his leukemia with a stem-cell transplant from a person who was born with a genetic mutation causing immunity to HIV infection. Following the transplant, Mr. Brown was able to stop HIV treatment without experiencing a return of his HIV disease
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achieved by antiretroviral therapy alone
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Superbugs may have a soft spot, after all - 1 views

www.sciencedaily.com/...130226092130.htm

Superbugs

shared by Katelyn Madigan on 27 Feb 13 - No Cached

Whitney Hopfauf liked it

identified a weakness in at least one superbug that scientists may be able to medically exploit
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discovered that two proteins already present in E. coli cells -- RbfA and KsgA -- need to be in balance with each other in order for ribosomes to function
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RbfA does not exist in humans
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Why sourdough bread resists mold - 1 views

www.sciencedaily.com/...130221194239.htm

resistance bread mold

shared by Katelyn Madigan on 22 Feb 13 - No Cached

sourdough bread differs from ordinary bread in having an extra fermentation step, over and above yeast fermentation. This step is mediated by lactic acid bacteria, typically of the genus Lactobacillus
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L. hammesii produced substantial quantities of hydroxylated monounsaturated fatty acids
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A second antifungal fatty acid produced by cereal enzymes
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