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Matti Narkia

Vitamin D may curb diabetes - Pharmacy News - 0 views

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    A New Zealand study has found that South Asian women with insulin resistance improved markedly after taking vitamin D supplements

    Nutrition researcher Pamela von Hurst of the Institute of Food, Nutrition and Human Health at Albany, said while diet and exercise played a major part in the onset of type-2 diabetes, her findings reinforced the importance of vitamin D from the sun and supplements to prevent type-2 diabetes.

    Initial screening of 235 Auckland women from India, Pakistan and Sri Lanka aged 20 and older, revealed 47 per cent were insulin deficient and 84 per cent were vitamin D deficient. The 81 recruited for the study were split into two groups for a randomised controlled trial and given a vitamin D supplement or placebo. As well as an improvement in insulin resistance among those who took vitamin D for six months, Ms Von Hurst said post-menopausal women in the study also showed a reduced rate of bone breakdown.
Matti Narkia

Vitamin-D supplements benefit diabetic Indian women - 0 views

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    "Women from India, Pakistan and Sri Lanka with insulin resistance showed marked improvement after taking vitamin D supplements, says a study.

    Von Hurst, nutrition lecturer at the Institute of Food, Nutrition and Human Health at Albany, conducted the study for her doctoral thesis.

    Insulin resistance is largely symptom-free and sufferers are unaware of their condition. 'Once it has fully developed into type-2 diabetes, it can be treated, but not cured,' says Von Hurst.

    Von Hurst says that while diet and exercise play a major part in the onset of type-2 diabetes, her findings reinforce the importance of vitamin D from the sun and supplements to prevent type-2 diabetes. She also found evidence of vitamin D increasing bone strength in older women.
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Matti Narkia

Vitamin D supplementation reduces insulin resistance in South Asian women living in New... - 0 views

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    Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient - a randomised, placebo-controlled trial.
    von Hurst PR, Stonehouse W, Coad J.
    Br J Nutr. 2009 Sep 28:1-7. [Epub ahead of print]
    PMID: 19781131

    In conclusion, improving vitamin D status in insulin resistant women resulted in improved IR and sensitivity, but no change in insulin secretion. Optimal vitamin D concentrations for reducing IR were shown to be 80-119 nmol/l, providing further evidence for an increase in the recommended adequate levels. Registered Trial No. ACTRN12607000642482.
Matti Narkia

Vitamin D replacement in Asians with diabetes may increase insulin resistance. - 0 views

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    Vitamin D replacement in Asians with diabetes may increase insulin resistance.
    Taylor AV, Wise PH.
    Postgrad Med J. 1998 Jun;74(872):365-6.
    PMID: 9799895

    We report three cases of vitamin D replacement in British Asians with vitamin D deficiency and non-insulin-dependent diabetes mellitus. In all cases, replacement resulted in an increase in insulin resistance and a deterioration of glycaemic control
Matti Narkia

Hypovitaminosis D is associated with insulin resistance and {beta} cell dysfunction -- ... - 0 views

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    Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction.
    Chiu KC, Chu A, Go VL, Saad MF.
    Am J Clin Nutr. 2004 May;79(5):820-5.
    PMID: 15113720

    Conclusions: The data show a positive correlation of 25(OH)D concentration with insulin sensitivity and a negative effect of hypovitaminosis D on ß cell function. Subjects with hypovitaminosis D are at higher risk of insulin resistance and the metabolic syndrome. Further studies are required to explore the underlying mechanisms.
Matti Narkia

Baseline Serum 25-Hydroxy Vitamin D Is Predictive of Future Glycemic Status and Insulin... - 0 views

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    Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000.
    Forouhi NG, Luan J, Cooper A, Boucher BJ, Wareham NJ.
    Diabetes. 2008 Oct;57(10):2619-25. Epub 2008 Jun 30.
    PMID: 18591391
    doi: 10.2337/db08-0593

    CONCLUSIONS: This prospective study reports inverse associations between baseline serum 25(OH)D and future glycemia and insulin resistance. These associations are potentially important in understanding the etiology of abnormal glucose metabolism and warrant investigation in larger, specifically designed prospective studies and randomized controlled trials of supplementation.
Matti Narkia

Variations in Vitamin D-Binding Protein (Group-Specific Component Protein) Are Associat... - 0 views

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    In conclusion, genetic variations of DBP are associated with insulin resistance in Japanese with normal glucose tolerance, which might contribute to the development of type 2 diabetes.

    Variations in vitamin D-binding protein (group-specific component protein) are associated with fasting plasma insulin levels in Japanese with normal glucose tolerance.
    Hirai M, Suzuki S, Hinokio Y, Hirai A, Chiba M, Akai H, Suzuki C, Toyota T.
    J Clin Endocrinol Metab. 2000 May;85(5):1951-3.
    PMID: 10843180
Matti Narkia

Vitamin D and disease prevention with special reference to cardiovascular disease - Ent... - 0 views

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    Zittermann A.
    Vitamin D and disease prevention with special reference to cardiovascular disease.
    Prog Biophys Mol Biol. 2006 Sep;92(1):39-48. Epub 2006 Feb 28. Review.
    PMID: 16600341 [PubMed - indexed for MEDLINE]
Matti Narkia

The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of In... - 0 views

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    Pittas AG, Harris SS, Stark PC, Dawson-Hughes B.
    The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Non-diabetic Adults.
    Diabetes Care. 2007 Feb 2; [Epub ahead of print]
    PMID: 17277040 [PubMed - as sup
Matti Narkia

Vitamin D status and parathyroid hormone in obese children before and after weight loss... - 0 views

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    Reinehr T, de Sousa G, Alexy U, Kersting M, Andler W.
    Vitamin D status and parathyroid hormone in obese children before and after weight loss.
    Eur J Endocrinol. 2007 Aug;157(2):225-32.
    PMID: 17656603 [PubMed - in process]
Matti Narkia

Correlation between vitamin D3 deficiency and insulin resistance in pregnancy - Wiley I... - 0 views

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    Maghbooli Z, Hossein-Nezhad A, Karimi F, Shafaei AR, Larijani B.
    Correlation between vitamin D(3) deficiency and insulin resistance in pregnancy.
    Diabetes Metab Res Rev. 2007 Jul 2; [Epub ahead of print]
    PMID: 17607661 [PubMed - as supplied by publish
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