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Peripheral metabolism of thyroid hormones: a revie... [Altern Med Rev. 2000] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...10956378 hypothyroidism hypothyroid T4 T3
shared by Nathan Goodyear on 20 Dec 10 - No Cached
  • The common feature of these disorders is a low level of circulating T3, with generally normal to slightly elevated blood T4 levels and either normal or slightly suppressed TSH levels. This pattern of altered thyroid hormone levels is generally agreed to be a result of impairment in extra-thyroidal peripheral metabolism
  • Nathan Goodyear on 20 Dec 10
     
    thyroid replacement is not just about T4 (synthroid); but about T3, which is 5.4 x more potent
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The Role of Selenium in Thyroid Hormone Action -- BERRY and LARSEN 13 (2): 207 -- Endoc... - 0 views

edrv.endojournals.org/...207 selenium hypothyroidism
shared by Nathan Goodyear on 20 Dec 10 - No Cached
  • Nathan Goodyear on 20 Dec 10
     
    selenium deficiency results in low thyroid function: yes a mineral.
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[Functional states of pituitary-ovary, adrenal and... [Zhonghua Fu Chan Ke Za Zhi. 1998... - 0 views

www.ncbi.nlm.nih.gov/...10682483 PCOS LH insulin hypothyroidism androgens testosterone resistance
shared by Nathan Goodyear on 17 Dec 10 - No Cached
  • CONCLUSION: It appears that ovarian androgen excess in women with PCOS is mainly LH-dependent in Group 1 and insulin-dependent in Group 2. Enhanced adrenal activity may contribute to both hyperandrogenism and insulin resistance in this syndrome, and subclinical hypothyroidism may exist in affected subjects, especially of Group 1.
  • Nathan Goodyear on 17 Dec 10
     
    PCOS is not a birth control pill deficiency, but a complex hormonal imbalance
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Thyroid Hormone Replacement - One Hormone or Two? - NEJM - 0 views

www.nejm.org/...NEJM199902113400611 thyroid T4 T3 armour
shared by Nathan Goodyear on 17 Dec 10 - No Cached
  • Nathan Goodyear on 17 Dec 10
     
    Patients feel better taking both T4 and T3 compared to those taking just T4
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Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabo... - 0 views

www.fasebj.org/4977 mitochondria metabolism aging
shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • Our study suggests long-lived, genetically specified Mit mutants employ a novel metabolism and that life span may well arise as a function of metabolic state.
  • Nathan Goodyear on 16 Dec 10
     
    Mitchondria, metabolism,  and aging
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Clinical controversies in screening women for thyr... [J Midwifery Womens Health. 2006 ... - 0 views

www.ncbi.nlm.nih.gov/...16647667 TSH screening
shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • In November 2002, the American Association of Clinical Endocrinologists (AACE) released new guidelines for clinical practice for the diagnosis and treatment of hyperthyroidism and hypothyroidism, which includes a new thyroid-stimulating hormone (TSH) reference range of 0.3 to 3.0 mIU/
  • Nathan Goodyear on 16 Dec 10
     
    TSH "screening" needs to be between 0.3 and 3 according to American Association of Clinical Endocrinologists
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Subclinical Thyroid Dysfunction: A Joint Statement on Management from the American Asso... - 0 views

jcem.endojournals.org/...581 thyroid hypothyroidism subclinical
shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • the potential benefits of early detection and treatment of subclinical thyroid dysfunction significantly outweigh the potential side-effects that could result from early diagnosis and therapy
  • Nathan Goodyear on 16 Dec 10
     
    Joint statement on early treatment of thyroid disease and subclinical thyroid dysfunction from The american association of clinical endocrinologists, the American Thyroid Association, and the Endocrine Society
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TSH may not be a good marker for adequate thyroid ... [Wien Klin Wochenschr. 2005] - Pu... - 0 views

www.ncbi.nlm.nih.gov/...16416346 TSH thyroid hormone replacement therapy
shared by Nathan Goodyear on 16 Dec 10 - No Cached
  • TSH levels used to monitor substitution, mostly regulated by intracellular T3 in the pituitary, may not be such a good indicator of adequate thyroid hormone action in all tissues
  • Nathan Goodyear on 16 Dec 10
     
    TSH may not be a good marker for adequate thyroid hormone replacement therapy.
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Omega Research - 0 views

www.omega-research.com/researchview.php omega-3 alzheimer's disease amyloid oxidative stress
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 limit amyloid and oxidative damage; thus may decrease alzheimer's disease risk
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Environmental Lead Exposure and Progression of Chronic Renal Diseases in Patients witho... - 0 views

www.nejm.org/...NEJMoa021672 EDTA chelation chronic renal insufficiency
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Low-level environmental lead exposure may accelerate progressive renal insufficiency in patients without diabetes who have chronic renal disease. Repeated chelation therapy may improve renal function and slow the progression of renal insufficiency
  • Nathan Goodyear on 15 Dec 10
     
    EDTA chelation aids in lead induced chronic renal insufficiency
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The Toxicology of Mercury - Current Exposures and Clinical Manifestations - NEJM - 0 views

www.nejm.org/...NEJMra022471 Mercury toxins toxicology
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • The Toxicology of Mercury — Current Exposures and Clinical Manifestations
  • Nathan Goodyear on 15 Dec 10
     
    Nice review of the toxicology of Mercury
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Lead-Chelation Therapy -- A Treatment for Chronic Renal Disease? - General Medicine - 1 views

general-medicine.jwatch.org/...1 EDTA chelation renal insufficiency lead
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Therapy with EDTA delayed the progression of chronic renal insufficiency in patients with high-normal body lead burdens
  • Nathan Goodyear on 15 Dec 10
     
    Therapy with EDTA delayed the progression of chronic renal insufficiency in patients with high-normal body lead burdens
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Effects of ethyl-eicosapentaenoic acid omega-3 fat... [Menopause. 2009 Mar-Apr] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...19034052 omega-3 omega EPA hot flashes
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Effects of ethyl-eicosapentaenoic acid omega-3 fatty acid supplementation on hot flashes and quality of life among middle-aged women: a double-blind, placebo-controlled, randomized clinical trial.
  • Supplementation with E-EPA omega-3 fatty acid reduced HF frequency and improved the HF score relative to placebo
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 aids in hot flash relief
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Ethyl-eicosapentaenoic acid for the treatment of psychological distress and depressive ... - 0 views

www.ajcn.org/...641.full Omega-3 depression
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • he 8-wk changes in PD and depressive scales improved significantly more with E-EPA than with placebo.
  • Nathan Goodyear on 15 Dec 10
     
    omega-3 improves depressive and psychological distress symptoms
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Omega Research - 0 views

www.omega-research.com/researchview.php Omega-3 vitamin C E antioxidants oxidative stress infertility
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • These data have important implications for the supplementation of a combination of omega-3 fatty acids and antioxidants in the successful management of female infertility.
  • Nathan Goodyear on 15 Dec 10
     
    omega 3 and antioxidants aid in infertility
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Omega Research - 0 views

www.omega-research.com/researchview.php omega Omega-3 diabetes
shared by Nathan Goodyear on 15 Dec 10 - No Cached
  • Nathan Goodyear on 15 Dec 10
     
    higher omega-3 intake = lower type 2 diabetes
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Insulin Receptor Expression and Function in Human Breast Cancer Cell Lines - Cancer Res - 0 views

cancerres.aacrjournals.org/...3924.short insulin breast cancer receptors
shared by Nathan Goodyear on 11 Dec 10 - No Cached
  • This present study indicates therefore that in breast cancer cell lines there are functional insulin receptors that regulate breast cancer cell growth.
  • Nathan Goodyear on 11 Dec 10
     
    breast cancer cells express high functioning insulin receptors
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The syndrome of irreversible lithium-effectuated n... [Clin Neuropharmacol. 2005 Jan-Fe... - 0 views

www.ncbi.nlm.nih.gov/...15714160 Lithium neurotoxicity
shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • Nathan Goodyear on 10 Dec 10
     
    Silent but irreversible lithium-induced neurotoxicity
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Antipsychotic drug use and mortality in older adul... [Ann Intern Med. 2007] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...17548409 anti-psychotics neuroleptics
shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • Atypical antipsychotic use is associated with an increased risk for death compared with nonuse among older adults with dementia
  • Nathan Goodyear on 10 Dec 10
     
    up to 1.55 x increase risk of death with antipsychotic use
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Predicting the long-term risk of tardive dyskinesi... [J Clin Psychiatry. 1993] - PubMe... - 0 views

www.ncbi.nlm.nih.gov/...8098030 Neuroleptics Tardive Dyskinesias
shared by Nathan Goodyear on 10 Dec 10 - No Cached
  • , we estimate the risk of persistent TD to be 32% after 5 years of neuroleptic exposure (95% confidence interval [CI] = 23%-43%), 57% after 15 years of exposure (95% CI = 47%-66%), and 68% after 25 years of exposure
  • Nathan Goodyear on 10 Dec 10
     
    Neuroleptics significantly increase risk of Tardive Dyskinesias: we should think before we prescribe
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