Among women in the general US population, simultaneous screening with CA-125 and transvaginal ultrasound compared with usual
care did not reduce ovarian cancer mortality
In November 2002, the American Association of Clinical Endocrinologists (AACE) released new guidelines for clinical practice for the diagnosis and treatment of hyperthyroidism and hypothyroidism, which includes a new thyroid-stimulating hormone (TSH) reference range of 0.3 to 3.0 mIU/
Measurement of salivary IgA AGA provided excellent discrimination between those children with coeliac disease and the control groups, and our study suggests that it may provide a rapid, non-invasive method of screening for this disease before intestinal biopsy
new study sheds serious doubt on the benefit of breast MRI for breast cancer screening. NO correlation to improved survival can be drawn. Conclusion: "...to date do not show clear benefit for MRI."
The vast majority (88%) did not screen cardiac patients for TDS.
Testosterone deficiency has a prevalence of 7% in the general population, rising to 20% in elderly males
Males with CAD have lower testosterone levels than those with normal coronary angiograms of the same age,5 suggesting that the prevalence of testosterone deficiency is much higher in the CAD population
Men with hypertension, another established risk factor for CAD, have lower testosterone compared to normotensive men
Recent meta-analyses showed that testosterone levels are generally lower among patients with metabolic syndrome, regardless of the various definitions of metabolic syndrome that are used
Testosterone (total and bioavailable) and sex-hormone binding globulin (SHBG) are inversely associated with the prevalence of metabolic syndrome in men between the ages of 40 and 80, and this association persists across racial and ethnic backgrounds
ower levels of testosterone and SHBG predict a higher incidence of metabolic syndrome.
Low testosterone levels have been related to increased insulin resistance and cardiovascular mortality,12 even in the absence of overt type 2 diabetes mellitus.
testosterone levels (total and bioavailable) in middle-aged men are inversely correlated with insulin resistance
The Massachusetts Male Aging Study (MMAS) demonstrated that low levels of testosterone and SHBG are independent risk factors for the development of type 2 diabetes,
Andropausal men (age 58 ± 7 years) have a higher maximal carotid artery intima-media thickness
There is an inverse linear correlation between body mass index (BMI) and wait-to-hip ratio with testosterone and insulin-like growth factor-1 levels.
Testosterone supplementation for 1 year in hypogonadal men has been shown to cause a significant improvement in body weight, BMI, waist size, lipid profile, and C-reactive protein levels
TRT for 3 months in hypogonadal men with type 2 diabetes significantly improved fasting insulin sensitivity, fasting blood glucose and glycated hemoglobin.
Testosterone replacement can improve angina symptoms and delay the onset of cardiac ischemia, likely through a coronary vasodilator mechanism
ADT is associated with an increased risk of cardiovascular events, including myocardial infarction and cardiovascular mortality.
ADT significantly increases fat mass, decreases lean body mass,29,30 increases fasting plasma insulin and decreases insulin sensitivity31 and increases serum cholesterol and triglyceride levels
Startling study on the knowledge of Testosterone and cardiovascular disease in general practitioners and cardiologists in Canada. Eight-eight percent did not screen patients with cardiovascular disease for low Testosterone. A whopping 67% of physicians did not know that low T was a risk factor for cardiovascular disease, yet 62% believed Testosterone would increase exercise tolerance.
The lack of knowledge displayed by physicians today is staggering and is an indictment of the governing bodies. This was a survey conducted in Canada so there are obvious limitations to the strength/conclusion of this study.
Article looks at proposed 25 biomarkers to screen for Head and Neck squamous cancer. Most of these could be used for all cancers as they are inflammatory cytokines.
In conclusion we recommend the overnight dexamethasone suppression test with measurement of salivary cortisol as a screening test for Cushing's syndrome.
"cortisol measurement is therefore a primary method of choice in the screening of patients suspected of having Cushing's syndrome". This study compared plasma, salivary, and urinary tests. salivary testing of cortisol is settled. Safe, reliable, and preferred method of evaluation.
23% increase in autism in white children. That is now 1 in 88. The news is worse for black children (91% increase) and even worse for hispanics (110% increase). And no, this is not due to an increase in screening as some would propose.
TSH is not a reliable reproducible reflection of tissue T3 levels. In fact, in many ways TSH is merely just a screening tool. Research has shown that inflammation decreases TSH levels.
This article reveals how data is massaged to promote a viewpoint. In this case mammograms. Don't let your passions get the best of you, objectively review the data. Scientists are not doing that these days.
Mammograms do help and are needed in the screening, however, mammograms do cause harm and help to promote the same disease it seeks to detect early. This is in some cases. Also, remember, mammograms are early detection, not prevention.