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Nathan Goodyear

Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. - PubMed - NCBI - 0 views

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    Astaxanthin at 20 mg found to reduce oxidized LDL and other oxidative stress biomarkers as assessed by Malondialdehydy, SOD, Isoprostane, and TAC.  The dose was 20 mg for 12 weeks. This higher dose was associated with minimal side effects--red stools.
Nathan Goodyear

Fermented wheat germ extract inhibits glycolysis/p... [J Biol Chem. 2002] - PubMed result - 0 views

  • Avemar exhibits about a 50-fold higher IC(50) (10.02 mg/ml) for peripheral blood lymphocytes to induce a biological response, which provides the broad therapeutic window for this supplemental cancer treatment modality with no toxic effects.
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    Fermented wheat germ extract (Avemar) shows benefit in cancer treatment with no toxic side effects
Nathan Goodyear

The effect of statins on testosterone in men and wom... [BMC Med. 2013] - PubMed - NCBI - 0 views

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    Meta-analysis finds that Testosterone lowers Testosterone levels in both men and women.  I love the authors concluding remarks: "whether this is a detrimental side effect..."  in men, there is no doubt.
Nathan Goodyear

Pharmaceuticals | Free Full-Text | Chronic Cannabigerol as an Effective Therapeutic for Cisplatin-Induced Neuropathic Pain - 0 views

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    10 mg/kg in males and 15 mg/kg in females without side effects
wheelchairindia9

Tricycle For Disabled Children - 0 views

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    The tricycles are individually designed to meet the needs of each disabled child and help provide physiotherapy, build muscle tone and promote play. Italso help benefit growth and development in children with disabilities, enabling them to keep active and retain their independence. Disabled children get huge physical and emotional benefits from having the specially tricycles, which are each custom made to suit the individual child's needs. Riding a tricycle provides both fun and fitness, and is a therapeutic activity that allows children to exercise their lower extremities. As the muscles move through cycling motions, they are flexed, extended and stretched. This range of motion is crucial for children with disabilities, because muscles are incapable of keeping up with bone growth unless fully extended. Tricycles are provided to severely disabled children and adults and come in two sizes, 20 inch and 24 inch models. These trikes are grant funded and to qualify for one of these, an individual must suffer from a condition such as, but not limited to, Cerebral Palsy, Down Syndrome, Traumatic Brain Injury or Autism. Trunk support system is ideal for riders who have trouble remaining upright while seated. An optional headrest is available. A headrest can be purchased with either a flat or contoured headpiece, and adjusts both horizontally and vertically for optimum positioning. The Front Pulley System maintains a level pedal position for children whose extreme tone forces the front of the pedal downward. Turn the oval knob to raise and lower the handlebar. A handbrake for the conventional handlebar will arrive installed on Large tricycle. Open access combined with a low transfer step makes it easy to get on and off trikes. Tricycle Deluxe Double Hand Drive: Frame : Made by E.R.W. Tubes 38.0 mm-16 G. 25.4 mm & 22.22 mm- 18 G. Seat & Back : M S, C.R.C. Sheet. Seat Size 18"x 16" Wheel Size : Wheel Diameter 24"x 1 1/2" Tyre and Tube Standard Company. Pa
wheelchairindia9

Karman S-Ergo 115 - 0 views

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    Ergonomic wheelchairs have been tested and proven to be effective for relieving pressure throughout the body; this is confirmed by pressure chart mapping. Feeling comfortable on a wheelchair is something every user demands out of their new wheelchair, the ergonomic cushion that is included with the ergonomic series provides a level of comfort that is unparalleled. Ergonomic Transport Wheelchair provides the perfect shape to fit the human body to relieve pressure, increase stabilization, weight distribution and lower the risk of pressure sores and scoliosis. Lightweight Ergonomic Wheelchair features wide arm pads for extra support, folding back rest, detachable swing-away footrests, and a Tube-in Center foot-plate that provides extra support for the leg muscles. This wheelchair can hold up to daily use and is excellent for traveling. Ergonomic features flip-back armrest and swing away footrests. A lightweight frame that is 25 lbs. without footrests and a folding backrest allows easy travel or storage. The chair comes equipped with a padded anti-bacterial upholstery that is comfortable and washable. Karma Ergo Lite 2501 Wheelchair: The extremely lightweight Ergo Lite 2501 Transport Wheelchair weighs only 8.16 kg. and features an ergonomically-designed seat and backrest, making it one of the most comfortable transport chairs on the market. The folding seat and backrest make the S-Ergo ideal for storage or travel, and the built in AEGIS anti-bacterial cushion provides added comfort and support. Despite its light weight, the S-Ergo features a 115 kg. weight capacity along with large, 14" flat-free polyurethane rear tires. Karma Ergo Lite 2501 Wheelchair Features: Lightest transporter on the market! Patented S-Style Ergonomic Seat Frame 6061 T-6 Aircraft-grade Aluminum Only 18 lb . (w/ footrests) Built in Silver Aegis Anti-bacterial Cushion Fixed Armrests w/Concaved Armpads Pocket Behind Backrest & Small Carry Pouch on Each Armrest 6" x 1" Polyurethane
Nathan Goodyear

Ozone therapy: A clinical review - 0 views

  • Its basic function is to protect humans from harmful effects of UV radiation
  • Its effects are proven, consistent and with minimal side effects
  • Medical O3, used to disinfect and treat disease, has been around for over 150 years
  • ...11 more annotations...
  • O3 not only remedied infection, but also had hemodynamic and anti-inflammatory properties
  • Stimulation of oxygen metabolism
  • In fungi, O3 inhibits cell growth at certain stages
  • With viruses, the O3 damages the viral capsid and upsets the reproductive cycle by disrupting the virus-to-cell contact with peroxidation.
  • Inactivation of bacteria, viruses, fungi, yeast and protozoa: Ozone therapy disrupts the integrity of the bacterial cell envelope through oxidation of the phospholipids and lipoproteins
  • Activation of the immune system
  • 30 and 55 μg/cc
  • production of interferon and the greatest output of tumor necrosis factor and interleukin-2
  • Mechanism of action of O3 on the human lung
  • cascade of reactions like peroxidation of lipids leading to changes in membrane permeability,[41] lipid ozonation products (LOP) act as signal transducer molecules
  • Dietary antioxidants or free radical scavengers like vitamin E, C, etc., can prevent aforementioned effects of O3
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    Ozone therapy review
Nathan Goodyear

Treatment of Obesity-Related Complications with Novel Classes of Naturally Occurring PPAR Agonists - 0 views

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    natural PPAR agonists.  Maybe provide some of the anti-inflammatory improved lipid metabolism without the side effects found in their synthetic counterpart avandia
Nathan Goodyear

PLOS ONE: Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer - 0 views

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    IV vitamin C as adjuvant to chemotherapy in those with Pancreatic cancer, not found to be associated with side effects.
Nathan Goodyear

ScienceDirect.com - Physiology & Behavior - Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease - 0 views

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    Testosterone is known to provide anti-inflammatory signaling in men.  This study, inhibition of mitochondrial complex I (coQ dependent) resulted in lower testosterone in rat models.  One of the major side effects of statin therapy is poor memory and brain fog. Hmmm.
Nathan Goodyear

Risk Factors Associated With Cardiovascular Events During Testosterone Administration in Older Men With Mobility Limitation - 0 views

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    This study proves the problems rampant in science today.  This study looked at older men with mobility limitations: safe to say, not optimal health.  They give 10 grams of testosterone daily to these men.  Physiologic doses are 5-10 mg.  And they are surprise that there is an increase in side effects, here in this study CVD.  They did look at cytokines, I'll give them that; but they did not look at aromatase activity and E2, E1 levels which have been shown to be the driving forces behind these inflammatory cytokines in men.  Testosterone has in fact been shown to downregulate these inflammatory cytokines.  Poor study.  No conclusion can be taken from this study.
Nathan Goodyear

Bariatric Surgery Results in Cortical Bone Loss - 0 views

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    no surprise here.  Bariatric surgery was found to result in bone loss.  Disruption of the GI tract and absorption is going to result in malnutrition states and bone loss will be one of the side effects.
Nathan Goodyear

Huperzine a as potential treatment of Alzheim... [Chem Biodivers. 2011] - PubMed - NCBI - 0 views

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    Huperzine A at doses up to 400 mcg shown to benefit people with Alzheimer's disease, with no significant side effects.
Nathan Goodyear

Huperzine A for Alzheimer's disease. [Cochrane Database Syst Rev. 2008] - PubMed - NCBI - 0 views

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    Review of 6 trials on 454 patients found Huperzine A improved cognition and executive function with no serious adverse events in patients with Alzheimer's disease.  Yet, their conclusion is, "...inadequate evidence to make any recommendation..."   Does it improve executive cognitive function?   Yes.  Does in have serious side effects?  No.  And we are waiting on...?
Nathan Goodyear

Vitamins E and C are safe across a broad range of intakes - 0 views

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    high dose vitamin E and vitamin C are found to be safe.  As always, the majority of these studies did not include pre-treatment vitamin assessment to ensure a metabolic need.  To much of a good thing can be a bad thing.  Also, higher dosing of vitamins approach a medicinal use and an associated increase in side effects.
wheelchairindia9

Tynor Restrainer - 0 views

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    Tynor Restrainer Applications To manage combative or disoriented patient. Manage post anesthesia delirium. Patients with head injuries or recovering from seizures. Schizophrenia, mental illness, dementia, or side effects from their treatment. To limit the body movement. Maintain a particular position. Tynor Restrainer Features Cushiony & comfortable. Easy to tie and open. Strong and durable. Fits left, right, wrist & ankle. Tynor Restrainer Measurements Size Chart - Size Inches CM Universal 5-9.5 12.5-23.8
Nathan Goodyear

Stanford scientists discover multitude of drug side effects, interactions using new computer algorithm - Office of Communications & Public Affairs - Stanford University School of Medicine - 0 views

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    A proper title would have been, "are the drugs your are taking killing you?"
Nathan Goodyear

Efficacy and tolerability of oral and intramuscular S-adenosyl- l-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies - 0 views

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    Head to head study of SAMe and imipramine for major depression found SAMe to be equivalent in efficacy to imipramine, but with fewer side effects.
Nathan Goodyear

S-adenosylmethionine reduces the progress of... [Neurobiol Aging. 2012] - PubMed - NCBI - 0 views

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    SAMe helps to correct disordered homocysteine metabolism due to B- vitamin deficiency found in Alzheimer's disease.  SAMe show to reduce amyloid production, improve memory, decrease Tau, and reduced plaque formation.  Now, this was in a mice model, but SAMe as a methyl donor can benefit clients with dementia with minimal side effects.
Nathan Goodyear

Speech dysfunction due to trazodone-fluoxetine combination in traumatic brain injury, Brain Injury, Informa Healthcare - 0 views

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    common insomnia cocktail has powerful side effects
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