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Contents contributed and discussions participated by Nathan Goodyear

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Nathan Goodyear

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1332190/pdf/brjsmed00019-0063.pdf - 0 views

www.ncbi.nlm.nih.gov/...brjsmed00019-0063.pdf

endurance exercise endurance exercise endurance athletes athlete athletes marathon IV fluids intravenous

shared by Nathan Goodyear on 15 Jan 15 - No Cached
  • Nathan Goodyear on 15 Jan 15
     
    study finds IV hydration with glucose and larger volume did not recover as well as those with 100 ml  of IV fluids.  This conclusion is incomplete as the time differences between the 2 groups was significant--group 2 (2.5 L fluid group) finished much faster and studies have shown that these endurance athletes are more prone to dehydration, more significant weight loss, adverse effects from the event.  This likely explains the difference between the 2 groups.
Nathan Goodyear

25-Hydroxyvitamin D, 1,25-Dihydroxyvitamin D and Postoperative Outcome in Cardiac Surge... - 0 views

press.endocrine.org/...jc.2014-3013

vitamin D CVD cardiovascular disease heart health cerebrovascular CVA surgery

shared by Nathan Goodyear on 14 Jan 15 - No Cached
  • Nathan Goodyear on 14 Jan 15
     
    low vitamin D predicts increased risk of Major adverse cardiac and/or cerebrovascular events after cardiac surgery.  The definition of low D was <30.  A better study would have been to stratify by 10s the risk.
Nathan Goodyear

Intravenous Fluid Use in Athletes - 0 views

www.ncbi.nlm.nih.gov/...PMC3435915

IV nutrition intravenous fluids exercise sports medicine sports athlete athletes

shared by Nathan Goodyear on 13 Jan 15 - No Cached
  • The current data suggest that IV rehydration is faster than oral
  • There may be physiological benefits of decreased heart rate and norepinephrine in athletes rehydrated via IV route
  • Muscle damage during exercise in the heat was assessed by myoglobin and creatine kinase
  • ...4 more annotations...
  • Postexercise blood 1 hour and 24 hours showed no differences in circulating myoglobin or creatine kinase
  • IV administration of fluids can rapidly replace plasma volume
  • The rapid increase in plasma volume is transient, and no measureable difference between IV and oral prehydration exists after 15 minutes of exercise
  • The use of IV fluid may be beneficial for a subset of fluid sensitive athletes
  • Nathan Goodyear on 13 Jan 15
     
    IV nutrition pre-event, intra-event, and post-event for recovery.
Nathan Goodyear

Intravenous versus oral rehydration in athletes. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...20364876

IV intravenous fluids nutrition athlete athletes

shared by Nathan Goodyear on 13 Jan 15 - No Cached
  • Nathan Goodyear on 13 Jan 15
     
    to be read.
Nathan Goodyear

Effect of saline infusion on body temperature and endurance during ... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...2745343

IV intravenous fluid nutrition athlete athletes exercise

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  • Nathan Goodyear on 13 Jan 15
     
    to be read
Nathan Goodyear

Fluid replacement and glucose infusion during exercise prevent card... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...1757323

IV intravenous fluids athlete athletes exercise

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  • Nathan Goodyear on 13 Jan 15
     
    to be read
Nathan Goodyear

Intravenous Fluid Use in Athletes - 0 views

www.ncbi.nlm.nih.gov/...PMC3435915

IV intravenous fluid nutrition athletes athlete sports medicine sports exercise

shared by Nathan Goodyear on 13 Jan 15 - No Cached
  • Treatment of exercise-associated hyponatremia with hypertonic IV infusion to correct plasma sodium levels is also a standard and accepted use of IV fluid infusions
  • athletes who present for medical care with hypernatremia who cannot tolerate oral fluids can benefit from IV fluids
  • Vaporization of sweat accounts for 80% of heat loss in hot, dry atmospheric conditions. This mechanism of water loss is the major contributor for exercise-associated dehydration
  • ...30 more annotations...
  • The rate of water loss can be quantified through measurement of sweat rate
  • Pre- and postexercise body weight measurements are the most common means to estimate overall water loss but are condition specific
  • It appears that 1% to 2% body weight loss is well tolerated by the exercising athlete
  • Dehydration, defined as greater than 2% loss of body weight, can negatively affect performance
  • In highly trained endurance athletes, plasma volume and sodium serum concentration were preserved despite a 5% body weight loss
  • In Ironman triathletes, dehydration to 5% body weight loss did not correlate with occurrence of medical complications
  • hydration should begin hours prior to exercise, especially if known deficits are present, and fluids should be consumed at a slow, steady rate, with 5 to 7 mL/kg taken 4 hours prior to exercise
  • Sodium concentration did not produce significant changes in the rate of absorption but was primarily dependent on carbohydrate concentration
  • Replacing 150% of body weight loss over 60 minutes has been tolerated without complications
  • IV treatment of severe dehydration (&gt;7% body weight loss), exertional heat illness, nausea, emesis, or diarrhea, and in those who cannot ingest oral fluids for other reasons, is clinically indicated
  • A recent survey of the National Football League teams revealed that 75% (24 of 32) of the teams utilized IV infusion of fluids for prehydration in at least some otherwise healthy individuals
  • In the National Football League, an average of 1.5 L of normal saline was administered approximately 2.5 hours prior to competition
  • after 2 hours of exercise, the rectal temperature was 0.6° higher in the group not receiving IV infusion. Also, stroke volume and cardiac output were 11% to 16% lower in the control group versus the IV infusion group.
  • Recent evidence suggests the etiology of EAMC is related to muscle fatigue and neuronal excitability
  • no correlation between hydration status or electrolyte concentrations with EAMC
  • there may be a subset of muscle cramping that is associated with a loss of both body fluid and sodium
  • Glycerol is the primary agent for oral hyperhydration
  • elevation of plasma volume by 200 to 300 mL via dextran infusion resulted in 15% increase in stroke volume, 4% increase in VO2 max, and an increase in the exercise time to fatigue
  • Neither the tonicity nor mode of hydration resulted in improved speed of rehydration, greater fluid retention, or improved performance
  • There are beneficial anecdotal reports of EAMC treatment in elite and professional-level athletes with IV hydration during the course of an event
  • Plasma volume was better restored during rehydration with IV fluids at preexercise and 5 minutes of exercise. At 15 minutes, there was no difference between IV and oral rehydration
  • More rapid restoration of plasma volume was accomplished in the IV treatment group with no advantages over oral rehydration in physiological strain, heat tolerance, ratings of perceived effort, or thermal sensations
  • No difference was found in exercise time to exhaustion. IV and oral rehydration methods were equally effective. Heart rates were statistically higher in the oral rehydration group through 75 minutes of exercise, and there were higher increases in norepinephrine plasma concentrations
  • No significant differences between the groups were found for time to recovery, number of days with pain, number of days with stiffness, sleep disturbance, fatigue, rectal temperature, and loss of appetite
  • The current data suggest that IV rehydration is faster than oral
  • There may be physiological benefits of decreased heart rate and norepinephrine in athletes rehydrated via IV route
  • Postexercise blood 1 hour and 24 hours showed no differences in circulating myoglobin or creatine kinase
  • The use of IV fluid may be beneficial for a subset of fluid sensitive athletes
  • this should be reserved for high-level athletes with strong histories of symptoms in well-monitored settings.
  • Volume expanders may also be beneficial for some athletes
  • Nathan Goodyear on 13 Jan 15
     
    to be read
Nathan Goodyear

Deficient Glutathione in the Pathophysiology of Mycotoxin-Related Illness - 0 views

www.ncbi.nlm.nih.gov/...PMC3942754

myctotoxins glutathione GSH mold

shared by Nathan Goodyear on 12 Jan 15 - No Cached
  • Decreased function of the enzymes of glutathione production results in a microenvironment depleted of glutathione on a chronic basis
  • In humans, deficiency of glutathione can lead to chronic conditions [97], including chronic asthma
  • Nathan Goodyear on 12 Jan 15
     
    Mycotoxins deplete glutathione production and this depletion of glutathione is a portion go the toxicity/ill effects related to mycotoxins.  This article also points to evidence that glutathione can actually be employed in the treatment of mycotoxin related conditions/illnesses.
Nathan Goodyear

Glutathione supplementation improves macrophage functions in HIV. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...23409922

HIV glutathione GSH NAC N-acetylcysteine macrophages

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  • Nathan Goodyear on 12 Jan 15
     
    reduced glutathione, via increased oxidative stress, levels lost in HIV.  NAC and liposomal Glutathione increased innate immune function--macrophages.
Nathan Goodyear

The critical role of glutathione in maintenance of the mitochondrial genome. - Research... - 0 views

www.researchgate.net/...ce_of_the_mitochondrial_genome

glutathione GSH mitochondria cancer

shared by Nathan Goodyear on 12 Jan 15 - No Cached
  • Nathan Goodyear on 12 Jan 15
     
    Only abstract available.  Loss of glutathione leads to loss in mitochondrial DNA.
Nathan Goodyear

The endurance athletes heart: acute stress and chronic adaptation -- George et al. 46 (... - 0 views

bjsm.bmj.com/...i29.full

heart health endurance athletes endurance exercise athletes athletic heart

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    acute and chronic heart changes to endurance training/events.
Nathan Goodyear

https://www.cayugamed.org/docs/Nutrition_Update_for_the_Ultraendurance_Athlete%208.pdf - 0 views

www.cayugamed.org/...Ultraendurance_Athlete%208.pdf

endurance athletes endurance exercise nutrition athletes athlete

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    Nutrition for ultra endurance.  To be read.
Nathan Goodyear

http://www.msma.org/docs/communications/momed/Excessive_Endurance_Exercise_and_Heart_Di... - 0 views

www.msma.org/..._Disease_MOMED_JulyAug2012.pdf

heart disease endurance exercise exercise marathons triathlon endurance athletes heart health disease

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    great review of data on cardiac damage associated with extreme endurance training.  These EEEs, that they are called, are rare in those < 40 and usually involved genetic defects.  This article points to aggressive preventive testing in those > 50.
Nathan Goodyear

http://www.sportsperformancecentres.com/articles/interest/Endurance_Exercise_and_Protei... - 0 views

www.sportsperformancecentres.com/...se_and_Protein_Consumption.pdf

endurance athletes exercise endurance exercise protein

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    white paper on protein for endurance athletes.
Nathan Goodyear

Ibuprofen use during extreme exercise: effects on oxidative stress ... - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...17596774

endurance athletes exercise athletesoxidative stress ibuprofen

shared by Nathan Goodyear on 10 Jan 15 - No Cached
  • Nathan Goodyear on 10 Jan 15
     
    ibuprofen associated with increased oxidative stress in extreme exercise.
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