Group items tagged

Chapter of Thyroid from oxford textbook of endocrinology and diabetes

British scientists said on Thursday (December 30) they would be studying whether higher doses of a cheap and widely used steroid called dexamethasone could work better for patients with severe Covid-19 compared to the standard low doses. Last year, the same scientists conducting the large trial, dubbed RECOVERY, showed that dexamethasone was able to save the lives of Covid-19 patients in what was called a "major breakthrough" in the coronavirus pandemic. They had found that a 6 mg daily dose of dexamethasone, which is used to reduce inflammation in diseases such as arthritis, cut death rates by around a third among the most severely ill Covid-19 patients in hospitals. "Given how quickly the Omicron variant is spreading, we can expect to see patients admitted to hospital with severe Covid-19 for a while to come," said Peter Horby, an Oxford University professor co-leading the trial.

polyunsaturated fats found to improve PCOS

animal study finds LPS, lipopolysaccharides, decreases Testosterone production at the level of the leydig cells in the testes.

Lupus associated with increased fungal infections.

Homeopathy significantly improves fibromyalgia over placebo

Great review on the multi-prong effect of metformin on cancer cells. Of particular to this article, is the effects on CSCs.

Nice brief synopsis of Waldenstrom's Macroglobulinemia.

Corticosteroids elevate glucose in patients with glioblastomas, compromising treatment and shortening survival.

New prospective study of 1023 patients finds that high-insulogenic diet, also know as a traditional American diet, high glycemic, high sugar diet... is associated with an increased risk of cancer recurrence and mortality compared to low insulogenic diet.  The authors concluded that this would be beneficial for after surgical resection in people with stage III colon cancer. My question, is why wait on the development of cancer: use a low-insulogenic diet to prevent the cancer all together or when diagnosed implement immediately.  Why wait? Treat early! Prevent!

Great review of the Wnt/Beta-catenin pathway in initiation and progress of cancer.  The paper also highlights the common naturally occuring therapies to block this pathway: Flavonoids, curcumin, EGCG, green tea polyphenols, resveratrol, retinoids, lycopenes, lupeol, isothiocyanates.

mycoplasma as a potential causative factor in RA.

older, but good review on the gluamine-cancer connection.

Cancer will soon overtake cardiovascular disease as the #1 cause of mortality in the US and worldwide as happened in 12 European countries. The current dogma for cancer treatment is not working; the goal must be prevention. The 12 countries include: Spain, France, Belgium, Denmark, Italy, Israel, Luxembourg, The Netherlands, Norway, Portugal, Slovenia, and UK.

Maternal obesity increases cancer risk in offspring.

To be read

great read on low T via BLSA

High HDL found to actually increase cardiovascular risk in men and women. Peak benefit is found at 58 mg/dl and 77 mg/dl for men and women respectively. Higher levels of HDL >90 increased risk and all-cause mortality in men and women.