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Nathan Goodyear

PLoS ONE: Metabolic and Behavioral Compensations in Response to Caloric Restriction: Im... - 0 views

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    exercise and muscle very important to maintaining weight loss long-term.  Calorie restriction results in muscle mass loss and this will impair the ability to maintain weight loss long term
Nathan Goodyear

Effects of testosterone supplementatio... [Clin Endocrinol (Oxf). 2010] - PubMed - NCBI - 0 views

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    Men with hypogonadism, low T, Testosterone therapy reduced IL-1beta, TNF-alph, and CRP.   In addition, BMI and waist circumference was reduced.  Leptin and insulin decreased as well.
Nathan Goodyear

EMAS position statement: Testosterone replacement therapy in the aging male 0f. - PubMe... - 0 views

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    we need to get away from expert opinion statements like this. Not that their conclusions are incorrect; but it promotes laziness among physicians.  We physicians need to take control over the data by which we practice medicine and the only way we can do that is to read it.
Nathan Goodyear

Ferritin Level Is Positively Associated with Chronic Kidney Disease in Korean Men, Base... - 0 views

  • The overloading of body iron plays a role as an oxidative stressor
  • active radicals can affect lipids, proteins, and deoxyribonucleic acid (DNA), resulting in tissue injury and dysfunction
  • Excess iron causes oxidative stress and induces inflammation, leading to renal disease progression
  • ...4 more annotations...
  • Serum ferritin levels correlate with total body iron storage and systemic inflammation
  • The level of serum ferritin, an acute phase protein, is increased in an inflammatory environment
  • Previous studies have reported that elevated serum ferritin levels are associated with insulin resistance syndrome, hypertension, dyslipidemia, obesity, and metabolic syndrome as risk factors of CKD
  • elevated serum ferritin levels in hemodialysis patients predict higher mortality
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    great review and study: finds that elevated ferritin levels (> 200 ng/ml in men) was associated with increased chronic kidney disease in Korean study.
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