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Nathan Goodyear

Kent Holtorf: Long Term Weight Loss - More Than Will Power? - 0 views

www.huffingtonpost.com/...-weight-loss---m_b_192933.html

leptin reverse T3 weight loss

shared by Nathan Goodyear on 09 Mar 11 - No Cached
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • f greater than 10, it demonstrates there is a degree of leptin resistance contributing to an inability to lose weight
  • that it is difficult to lose weight with leptin resistance. High carbohydrate diets and in particular high-fructose corn syrup is shown to significantly increase leptin resistance and is a likely mechanism that high fructose corn syrup is associated with obesity
  • ...9 more annotations...
  • inactive thyroid hormone called thyroxine
  • it is problem inside the cell that the inactive T4 is not converted to T3 but rather to a mirror image of T3 called reverse T3. The reverse T3 has the opposite effect of T3, blocking the effects of T3 and lowering rather than increasing metabolism.
  • Studies are showing that stress and dieting (especially yo-yo dieting) can set this hormone into action as well as chronic illness such as diabetes, chronic fatigue syndrome and fibromyalgia.
  • As soon as the body senses a reduction in calories, the production of reverse T3 is stimulated to lower metabolism
  • With chronic dieting or stress, the body often stays in this "starvation mode" with elevated levels of reverse T3 and decreased levels of T3, which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • which is a major reason for the regaining of lost weight with dieting as well being the mechanism behind stress induced weight gain (it is not due to increased cortisol).
  • Studies are showing that such standard testing will miss 80% of thyroid dysfunction
  • ree T3/reverse T3 ratio
  • Nathan Goodyear on 09 Mar 11
     
    Fantastic review by Dr. Holtorf on reverse T3, leptin, and weight loss
Nathan Goodyear

Endocrine and metabolic effects of consuming bever... [Am J Clin Nutr. 2008] - PubMed r... - 0 views

www.ncbi.nlm.nih.gov/...19064538

fructose HCFS sucrose metabolic syndrome triglyceride fat obesity overweight

shared by Nathan Goodyear on 20 Aug 11 - No Cached
  • Nathan Goodyear on 20 Aug 11
     
    fructose, HCFS, and sucrose increase triglyceride formation = fat
Nathan Goodyear

11β-HSD1 is the major regulator of ... [Proc Natl Acad Sci U S A. 2014] - Pub... - 0 views

www.ncbi.nlm.nih.gov/...24889609

11-betaHSD1 11-betaHSD adipose tissue obesity glucocorticoids cortisol

shared by Nathan Goodyear on 04 Jun 14 - No Cached
  • Nathan Goodyear on 04 Jun 14
     
    Study proposes that 11beta-HSD type 1 is the key to linking glucocorticoids and metabolic dysfunction.  The key point of this study is that it is the adipose tissue expression of 11beta-HSD type 1 that is the key.
Nathan Goodyear

PLOS ONE: Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men:... - 0 views

www.plosone.org/...10.1371%2Fjournal.pone.0100409

metabolic syndrome Total Testosterone Total Testosterone free free Testosterone SHBG BMI obese overweight men male hormone hormones

shared by Nathan Goodyear on 06 Aug 14 - No Cached
  • Nathan Goodyear on 06 Aug 14
     
    Association of low TT, SHBG, and free Testosterone with MetS was found in this study on men.  The association was influenced by BMI i.e. the overweight were found to have a higher association than the normal BMI.
Nathan Goodyear

The use of LeptiCore® in reducing fat gain and managing weight loss in patien... - 0 views

www.ncbi.nlm.nih.gov/...PMC2836327

LeptiCore weight loss obesity metabolic syndrome

shared by Nathan Goodyear on 17 Mar 17 - No Cached
ngoclinh91 liked it
  • Nathan Goodyear on 17 Mar 17
     
    lepticor aids weight loss.
Nathan Goodyear

The Ketogenic Diet and Sport: A Possible Marriage? : Exercise and Sport Sciences Reviews - 0 views

journals.lww.com/..._and_Sport___A_Possible.8.aspx

nutrition diet ketogenic ketogenic diet sports athletes exercise sports medicine

shared by Nathan Goodyear on 16 Nov 16 - No Cached
  • It is important to note that, although the blood level of glucose drops, it still remains at a physiological level (23), which is maintained through gluconeogenesis involving glucogenic amino acids and also glycerol released from triglycerides
  • “physiological ketosis” where KB levels may rise to 7 to 8 mmol L-1 (but without any pH change). In “pathological diabetic ketoacidosis,” on the other hand, ketonemia can exceed 20 mmol L-1 and also cause lowering of blood pH
  • in the initial phase of KD, about 16% of glucose comes from glycerol (released from triglyceride hydrolysis) and the bulk (60–65 g) from proteins via gluconeogenesis (proteins may be of either dietary or endogenous origin
  • ...5 more annotations...
  • the protein supply consumed during a KD “preserves,” as demonstrated, lean body mass
  • The importance of glycerol as a glucose source increases progressively during ketosis; in fact, glycerol passes from supplying 16% of total glucose to an average of 60% after many days (>7 d) of complete fasting (from 38% in lean individual to 79% in the obese).
  • The possible reasons for the effectiveness of KD for weight loss may be listed as follows, in order of evidence, strongest first: Figure 3Image Tools 1. Appetite reduction: protein satiety, effects on appetite-related hormones such as ghrelin, and possibly a sort of direct appetite-blocking effect of KB 2. Reduced lipogenesis and increased fat oxidation 3. A reduction in respiratory quotient may indicate a greater metabolic efficiency in fat oxidation 4. A thermic effect of proteins and increased energy usage by gluconeogenesis
  • all data regarding biochemical and molecular mechanisms suggest that it is very difficult to increase muscle mass during a KD; use of which really should be limited to the few days immediately before competition in bodybuilding.
  • a long-term KD can interfere with some muscle hypertrophy mechanisms and this could be counterproductive if the aim of the athlete is to gain muscle mass
  • Nathan Goodyear on 16 Nov 16
     
    Great read on the ketogenic  and its application to sports/training...
Nathan Goodyear

The Effects of Capsaicin and Capsiate on Energy Balance: Critical Review and Meta-analy... - 0 views

chemse.oxfordjournals.org/...103.short

capsaicin weight-loss overweight obesity capsiate metabolism energy balance

shared by Nathan Goodyear on 10 Feb 12 - No Cached
  • Nathan Goodyear on 10 Feb 12
     
    capsaicin shown to benefit weight loss.  Though just modestly.  But hey, anything to help.
Nathan Goodyear

ingentaconnect The Role of Orexin System in Antipsychotics Induced Weight Gain - 0 views

www.ingentaconnect.com/...art00002

orexin eating feeding weight-loss overweight obesity weight gain

shared by Nathan Goodyear on 02 Dec 11 - No Cached
  • The orexins modulate feeding behavior, some metabolic processes and arousal.
  • Nathan Goodyear on 02 Dec 11
     
    antipsychotics are associated with significant weight gain.  One proposed mechanism is the increased activation of orexin neurons in the areas of the brain (lateral hypothalamus and perifornical area) that regulate eating.  Amphetamines stimulate the same, just a drastically reduced levels
Nathan Goodyear

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced d... - 0 views

dl-web.dropbox.com/...0DM%2C%20and%20endotoxemia.pdf

bifidobacterium flora LPS metabolic endotoxemia Diabetes DM type II obesity inflammation overweight weight-loss

shared by Nathan Goodyear on 20 Jan 12 - No Cached
  • Nathan Goodyear on 20 Jan 12
     
    decreased bifidobacterium gut flora results in increased absorption of LPS in high fat diets resulting in endotoxemia. This plays a significant role in diabetes
Nathan Goodyear

Diagnosis and treatment of late-onset hypogonadism: Systematic review and meta-analysis... - 0 views

www.sciencedirect.com/...S1521690X13000481

low T Testosterone men male hormone hormones metabolic syndrome diabestes insulin resistance muscle obesity

shared by Nathan Goodyear on 04 Feb 14 - No Cached
  • Nathan Goodyear on 04 Feb 14
     
    Testosterone therapy is complex in hypogonadism.  Much of the marketing-based medicine of Low T today is in fact doping.  Increasing weight is clearly associated with a declining T level in men.  Testosterone therapy should be approach individually and therapies that use the one size fits all approach never work.  This is the case whether the use of synthetics or natural hormones are employed.  Testosterone has been shown to improve dysglycemia, MetS, reduce fat and increase muscle mass.  
Nathan Goodyear

Higher dietary fructose is associated with impaired hepatic adenosine triphosphate home... - 0 views

onlinelibrary.wiley.com/...34FD9FE5A86A5E9B8BE0490.d03t04

fructose uric acid ATP metabolic syndrome

shared by Nathan Goodyear on 17 Sep 13 - No Cached
  • Nathan Goodyear on 17 Sep 13
     
    uric acid used as marker for impaired ATP production in those with high fructose intake.
Nathan Goodyear

Interplay between lipids and branched-chain amino acids in development of insulin resis... - 0 views

www.ncbi.nlm.nih.gov/...PMC3695706

protein high diet insulin resistance metabolism obesity diabetes fatty acids essential

shared by Nathan Goodyear on 21 Oct 13 - No Cached
  • Nathan Goodyear on 21 Oct 13
     
    High branch chain amino acids can promote insulin resistance.  This study points out that long-term high protein dietary intake can actually have significant deleterious effects and lead to disease.  A high fat diet appears to be required for this effect.
Nathan Goodyear

JAMA Network | JAMA Surgery | Long-term Metabolic Effects of Laparoscopic Sleeve Gastre... - 0 views

archsurg.jamanetwork.com/article.aspx

obesity overweight bariatric surgery weight loss surgery

shared by Nathan Goodyear on 11 Aug 15 - No Cached
  • Nathan Goodyear on 11 Aug 15
     
    This study reveals what is wrong with a lot of the "standard practice" and literature in medicine today.  At 5 years, almost 50% of weight loss with gastric sleeve is regained--defined as excess weight loss (only 50% weight loss of excess weight).  That is a terrible 5 year outcome; not to mention the definition of success.  Even at 3 years, 31% had regained their "excess weight".  Add to that, the numbers of patients that followed up was terrible.  This poor follow up points to worse data outcomes than this study claims.
Nathan Goodyear

Testosterone supplementation in men with type 2 di... [Aging Male. 2003] - PubMed result - 0 views

www.ncbi.nlm.nih.gov/...12809074

testosterone supplementation diabetes obesity

shared by Nathan Goodyear on 02 Mar 11 - No Cached
  • the benefit of testosterone supplementation therapy exceeds the correction of symptoms of androgen deficiency and also includes glucose homeostasis and metabolic control.
  • Nathan Goodyear on 02 Mar 11
     
    Testosterone therapy in men with Diabetes
Nathan Goodyear

Low Testosterone Levels Are Common and Associated with Insulin Resistance in Men with D... - 0 views

jcem.endojournals.org/...1834

low testosterone insulin resistance diabetes overweight obesity

shared by Nathan Goodyear on 13 Apr 11 - No Cached
  • Low testosterone levels were independently associated with insulin resistance in men with type 1 diabetes as well as type 2 diabetes
  • Nathan Goodyear on 13 Apr 11
     
    low Testosterone associated with insulin resistance
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