Activity and expression of progesterone metabolizing 5α-reductase, 20α-hydrox... - 0 views
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Nathan Goodyear on 23 Jan 14Intra mammary progesterone metabolism and its associated metabolites found to be associated with tumorigenic activity in cell lines. This was independent from ER PR status. 5 alpha-pregnanes were found to be pro-tumor and 4-pregnanes were anti-tumor.