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Nathan Goodyear

Review: Contact sport-related chr... [Neuropathol Appl Neurobiol. 2011] - PubMed - NCBI - 0 views

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    CTE and sports related injuries
Nathan Goodyear

Immunoexcitotoxicity offers new insight in brain injury related research, care - 0 views

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    Great, though brief, review of immunoexcitotoxicity as it relates to CTE.
Nathan Goodyear

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy--A unif... - 0 views

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    Article discusses the immunoexcitotoxic process involved in chronic TBI. This is likely to be the underlying process involved in NFL and other football players delayed neurological effects. A similar process has been see in combat veterans returning from the theatre.
Nathan Goodyear

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unify... - 0 views

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    immunoexcitotoxicity and traumatic brain injury
Nathan Goodyear

Estriol treatment ameliorates disease in male... [J Neuroimmunol. 2004] - PubMed - NCBI - 0 views

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    Estriol found to be beneficial in experimental model of MS called EAE.  The effect would be through E3's preferential binding to ERbeta.  This study finds benefit in men and women.
Nathan Goodyear

Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression o... - 0 views

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    Huperzine A reduces EAE, an experimental MS model.  Thus, huperzine A has a anti-inflammatory effect in the brain.  
Nathan Goodyear

Oral acetyl-l-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a rand... - 0 views

  • decrease in the severity of both mental and physical fatigue and an increase in physical activity
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    Acetyl-L-carnitine reduces fatigue
Nathan Goodyear

Occupational Lead Poisoning - February 15, 1998 - American Family Physician - 0 views

  • The freely diffusible plasma fraction is distributed extensively throughout tissues, reaching highest concentrations in bone, teeth, liver, lungs, kidneys, brain and spleen
  • Inorganic lead does not undergo any metabolic transformation or digestion in the intestines, or detoxification in the liver.5
  • With chronic exposure over a long period of time, most absorbed lead ends up in bone
  • ...4 more annotations...
  • The total bodily content of lead is called the body burden; in a steady state, about 90 percent of the body burden is bound to bone.2
  • n general, lead is excreted quite slowly from the body (with the biologic half-life estimated at 10 years). Since excretion is slow, accumulation in the body occurs easily.2
  • hronic toxicity is an insidious illness with protean manifestations.3,6 Symptoms may include arthralgias, headache, weakness, depression, loss of libido, impotence and vague gastrointestinal difficulties.
  • Late effects may include chronic renal failure, hypertension, gout and chronic encephalopathy.6
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    occupational lead poisoning
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