Redox regulation in cancer - 0 views
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Mitochondrial electron-transport chain and other oxidizing agents are the prime pathways that generate excess ROS in vivo
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Permanent modification of genetic material resulting from the oxidative damage is one of the vital steps involved in mutagenesis that leads to carcinogenesi
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The most frequent DNA mutations caused during oxidative stress, initiated by ionizing radiation and other environmental carcinogens are 7,8-dihydro-8-oxoguanine (8-Oxo-G) and Thymine Glycol (TG)
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