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CLA, conjugated linoleic acid, supplementation reduces body fat mass

10 year f/u study of combined conjugated esterified estrogen and methyl testosterone in postmenopausal women finds no increase breast cancer risk.

Premarin increases the risk of stroke in postmenopausal women.  The risk of hip fracture was reduced and no change in Coronary Heart disease was found.

CLA, Omega-3, proves to be effective against Breast and Colon Cancer

CLA shown to reduce fat mass in postmenopausal women

CLA not shown to be beneficial in short-term weight loss

CLA shown to reduce fat mass in meta-analysis

Testosterone reduced the vascular benefits of Estrogen (conjugated equine Estrogen) in female rat model.  Testosterone is seeing widespread use in women with very little positive data.  In fact, the majority of data points to poor metabolic effects and poor outcomes.

HRT, particularily estrogen therapy, is shown to increase mild to moderate flares of lupus.

This was the WHI review of data as it pertains to dementia and cognitive decline in women.  The take home here is that the data provides little evidence for premarin with or without medroxyprogesterone acetate in > 65 for prevention of dementia.  However, this is in women > 65 and studies show that younger women do indeed receive benefit, especially in those with early ovary removal.  Another point here, MPA (medroxyprogesterone acetate) increases cognitive decline.  Just don't take MPA, it is a bad drug all the way around!

loss of ability to handle estrogen quinone metabolites is due to decreased detoxification capacity i.e.COMT, GSH...is associated with prostate carcinogenesis in rats.

DHA (omega 3) with paclitaxel (chemotherapy) increased efficacy by 61 x

Not only does DHA, Omega 3, increase effectiveness of chemotherapy drug Taxol, but it reduces the toxicity too.  Why doesn't every chemo regimen with Taxol, now include DHA?

certain amino acids pre and post exercise help to preserve muscle mass.  This has profound implications on fat loss and maintenance of fat loss long term