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Nathan Goodyear

SCD1 activity in muscle increases triglyceride PUFA content, exercise capacit... - 0 views

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    mice study suggests that increased linoleic acid increases lipid oxidation and increases metabolic rate and muscle performance.  The point is that some fat is good.  Too much Linoleic acid is pro-inflammatory which would promote adiposity.  The key is balance.
Nathan Goodyear

Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overw... - 0 views

  • Long-term supplementation with CLA-FFA or CLA-triacylglycerol reduces BFM in healthy overweight adults
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    CLA, conjugated linoleic acid, supplementation reduces body fat mass
Nathan Goodyear

Conjugated dienoic linoleate: a polyunsaturated fa... [Nutr Rev. 1995] - PubMed result - 0 views

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    CLA, Omega-3, proves to be effective against Breast and Colon Cancer
Nathan Goodyear

Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women - 0 views

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    CLA shown to reduce fat mass in postmenopausal women
Nathan Goodyear

Conjugated Linoleic Acid Supplementation for 8 Weeks Does Not Affect Body Composition, ... - 0 views

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    CLA not shown to be beneficial in short-term weight loss
Nathan Goodyear

Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans - 0 views

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    CLA shown to reduce fat mass in meta-analysis
Nathan Goodyear

Plasma fatty acids as predictors of glycaemia and type 2 diabetes. - PubMed - NCBI - 0 views

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    Palmitoleic acid and estimated D6D activity found to positively correlate with diabetes and worsening glucose control;  In contrast, linoleum acid found to be inversely associated with glucose control and Diabetes development.
Nathan Goodyear

PLOS ONE: Depletion of Brain Docosahexaenoic Acid Impairs Recovery from Traumatic Brain... - 0 views

  • The polyunsaturated fatty acids linoleic (LA, 18:2n-6) and linolenic acid (LNA, 18:3n-3) are essential fatty acids that cannot be synthesized by the body.
  • LNA serves as the precursor for long chain omega-3 fatty acids such as docosahexaenoic acid (DHA) while LA is converted into long chain omega-6 fatty acids such as arachidonic acid (AA)
  • DHA and AA are abundantly found in the brain, where these are stored mainly in membrane phospholipids
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  • DHA has been shown to increase neurite outgrowth and synaptogenesis, and promotes glutamatergic neurotransmission through increase in glutamate receptor subunit expression
  • DHA has been shown to be converted to anti-inflammatory, proresolving and neuroprotective mediators, such as resolvins [7] and protectins
  • AA is converted by cyclooxygenases into 2-series prostaglandins and 4-series leukotrienes, most of which exert pro-inflammatory effects
  • Supplementation of DHA exerts neuroprotective effects and has been reported to afford protection from diffuse axonal injury [11] and mixed brain injury [12] as well
  • severe depletion of membrane DHA in the brain renders mice significantly more susceptible to TBI and impairs recovery following the injury
  • Omega-3 fatty acids may serve as nutraceutical agents and precondition the brain to make it more resilient to injury
  • it can be suggested that enriching DHA in the brain may be prophylactic and protective against brain injury
  • severe DHA deficiency in the brain impairs functional recovery from TBI in terms of vestibulo-motor and cognitive deficits
  • DHA deficiency further elevates TBI-induced production of SBDPs
  • less neurons were found around the injury site of DHA deficient brain after TBI compared to the omega-3 fatty acid adequate group
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    mouse study finds prolonged recovery in DHA deficient mice compared to controls.
Nathan Goodyear

Dietary factors and growth and metabolism in experimental tumors - 0 views

  • Linoleic acid (LA), an essential n-6 polyunsaturated fatty acid (PUFA), was identified as an agent in dietary fat that is responsible for an up-regulation of tumor growth in vivo
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    High omega-6 intake in diet increases tumor growth
Nathan Goodyear

Evaluation of the antiobesity effects of an amino ... [J Int Med Res. 2010 May-Jun] - P... - 0 views

  • four amino acids (lysine, proline, alanine and arginine)
  • with or without conjugated linoleic acid to healthy overweight humans before and after exercising
  • When compared with the placebo group, several indicators, such as waist and hip circumferences, were found to have significantly decreased in the test supplement groups compared with the placebo
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  • These results suggest that ingestion of these supplements might enhance the fat-burning effects of exercise.
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    certain amino acids pre and post exercise help to preserve muscle mass.  This has profound implications on fat loss and maintenance of fat loss long term
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