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Dr. Jennifer Martinick

Dr Jennifer Martinick shares reviews on Surgical Hair Restoration Solutions - 0 views

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    Dr Jennifer Martinick is a respected hair transplant surgeon who ensures the most appropriate form of treatments based on patient's situation and requirements. Read a quick review on Surgical Hair Restoration Solutions provided.
Nathan Goodyear

John James a New Evidence Based Estimate of Patient Harms 2013 (1) - 0 views

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    Truly horrifying statistic not reported anywhere.  Hospital care has been associated with > 400,000 deaths annually.  The third leading cause of death is medical therapies/treatments.
Nathan Goodyear

Access : Prognostic and predictive value of plasma testosterone levels in patients rece... - 0 views

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    Higher base-line Testosterone levels associated with longer overall survival in men with prostate cancer.  The comparison was 32.7 months with higher T levels versus 22.4 months with lower T levels.  Anemia was also a poor prognostic variable.  Whether exogenous Testosterone therapy will change this is still unclear, but the authors suggest that this should play a role in whether to use salvage hormone therapy.
Nathan Goodyear

Prevalence of Symptomatic Androgen Deficiency in Men: The Journal of Clinical Endocrino... - 0 views

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    Prevalence of low T is 5-10% based on this study from 2007.
wheelchairindia9

Karma KP-80 - 0 views

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    Powerchair, is more compact and has a better turning radius, making it is easier to navigate narrow doorways and tight turns. Another advantage of the powerchair wheelchair is that its armchair joystick does not require an upright posture like an electric scooter's handlebars. Most powerchair wheelchairs can also be taken apart and stowed, while scooters usually can't. Powerchair wheelchairs are also usually less. Power Wheelchairs/Electric Wheelchairs is specially designed for Disabled and Handicapped People. They are recognized as the prominent manufacturer and supplier of a wide array of Power Wheelchairs. Variety of Power Wheelchairs for handicapped and disability product like: Variety of Power Wheelchairs: Karma KP 10-2 Power Wheelchair Karma KP 10-3 Power Wheelchair Karma KP 80 Power Wheelchair GM Lite Power Wheelchair Bronco Wheelchair Angel Wheelchair Bronco Wheelchair: Bronco Reclining Power Wheelchair Description: Comfort mobility is a professional Bronco Wheelchair and power scooter manufacturer established in 1978 in Taiwan. It operates with the policy of combining high quality with innovation. With dedication to research and development, Bronco wheelchair are exported around the world and earned solid reputation for its superior quality, comfort and convenience. Bronco wheelchair - comfortable, durable, designed for easy and healthy movement with full precautions. Bronco Reclining Power Wheelchair Specifications: Anchorage points Adjustable footplates LED front lights Detachable backrest Flip-back armrests Adjustable headrest Mechanic repairs Optional handbrake Power Wheelchair Features: Battery Power Wheelchair. Seat, base & battery quickly detach for easy storage and transportation Come with captain seat. With seat platform, the captain seat can be moved forward or backward using tools which is included. Adjustable armrest width and height. Footrests can be moved forward or backward for optimum placeme
Nathan Goodyear

Diet-induced obesity and low testosterone increase neuroinflammation and impair neural ... - 0 views

  • both obesity and low testosterone are also risk factors for neural dysfunction, including cognitive impairment [58–61] and development of AD
  • Levels of obesity and testosterone are often inversely correlated
  • diet-induced obesity causes significant metabolic disturbances and impairs central and peripheral nervous systems.
  • ...23 more annotations...
  • both obesity and low testosterone are linked with promotion of inflammatory pathways [70–72] and exert harmful actions on the central [73–75] and peripheral [29,76] nervous systems
  • In general, obesity-related changes were worsened by low testosterone and improved by testosterone treatment; however, this relationship was not statistically significant in several instances. Further, our data suggest that a common pathway that may contribute to obesity and testosterone effects is regulation of inflammation
  • fasting blood glucose levels were independently and additively increased by GDX-induced testosterone depletion and high-fat diet
  • testosterone treatment significantly reduced fasting glucose under both the normal and high-fat diets, demonstrating potential therapeutic efficacy of testosterone supplementation
  • fasting insulin, insulin resistance (HOMA index), and glucose tolerance, low testosterone tended to exacerbate and or testosterone treatment improved outcomes.
  • testosterone status did not significantly affect body weight
  • testosterone’s effects likely do not indicate an indirect result on adiposity but rather regulatory action(s) on other aspects of metabolic homeostasis
  • Prior work in rodents has shown diet-induced obesity induces insulin resistance in rat brain [63] and that testosterone replacement improves insulin sensitivity in obese rats [64]. Our findings are consistent with the human literature, which indicates that (i) testosterone levels are inversely correlated to insulin resistance and T2D in healthy [30,65] as well as obese men [66], and (ii) androgen therapy can improve some metabolic measures in overweight men with low testosterone
  • it has been shown that TNFα has inhibitory effects on neuron survival, differentiation, and neurite outgrowth
  • Our data demonstrate that low testosterone and obesity independently increased cerebrocortical mRNA levels of both TNFα and IL-1β
  • Testosterone status also affected metabolic and neural measures
  • many beneficial effects of testosterone, including inhibition of proinflammatory cytokine expression
  • neuroprotection [80,81], are dependent upon androgen receptors, the observed effects of testosterone in this study may involve androgen receptor activation
  • testosterone can be converted by the enzyme aromatase into estradiol, which is also known to exert anti-inflammatory [82] and neuroprotective [83] actions
  • glia are the primary sources of proinflammatory molecules in the CNS
  • poorer survival of neurons grown on glia from mice maintained on high-fat diet
  • Since testosterone can affect glial function [86] and improve neuronal growth and survival [87–89], it was unexpected that testosterone status exhibited rather modest effects on neural health indices with the only significant response being an increase in survival in the testosterone-treated, high-fat diet group
  • significantly increased expression of TNFα and IL-1β in glia cultures derived from obese mice
  • testosterone treatment significantly lowered TNFα and IL-1β expression to near basal levels even in obese mice, indicating a protective benefit of testosterone across diet conditions
  • IL-1β treatment has been shown to induce synapse loss and inhibit differentiation of neurons
  • Testosterone status and diet-induced obesity were associated with significant regulation of macrophage infiltration
  • testosterone prevented and/or restored thermal nociception in both diet groups
  • a possible mechanism by which obesity and testosterone levels may affect the health of both CNS and PNS
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    Study points to obesity and low Testosterone contribution of neuroinflammation.  No effect of body weight was seen with TRT.  This animal model found similar positive effects of TRT in insulin sensitivity.  Obesity and low T increase inflammatory cytokine production: this study found an increase in TNF-alpha and IL-1beta and TRT reduced TNF-alpha and IL-1beta to near base-line.  Testosterone is neuroprotective and this study reviewed the small volume of evaded that pointed to benefit from estradiol.  Testosterone's effect on glial survival was positive but not significant.  Obesity and low T were found to be associated with increased macrophage infiltration in the PNS with increased TNF-alpha and IL-1beta.   Testosterone therapy improved peripheral neuropathy via its positive effects on nocicieption.
wheelchairindia9

Karma Power Wheelchair KP-10.3 - 0 views

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    Electric wheelchairs, also called power chairs, are often a more suitable option for those who are physically unable to self propel a manual wheelchair.Power Wheelchairs/Electric Wheelchairs is specially designed for Disabled and Handicapped People. This are recognized as the prominent manufacturer and supplier of a wide array of Power Wheelchairs. Variety of Power Wheelchairs for handicapped and disability product like- Variety of Power Wheelchairs: Karma KP 10-2 Power Wheelchair Karma KP 10-3 Power Wheelchair Karma KP 80 Power Wheelchair GM Lite Power Wheelchair Bronco Wheelchair Angel Wheelchair Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach for easy storageand transportation. Come with captain seat. With seat platform, the captain seat can be moved forward or backward using tools which is included. Adjustable armrest width and height. Footrests can be moved forward or backward for optimum placement. Quick release battery pack for easy storage and battery pack change. Karma KP 10-2 Power Wheelchair is a lightweight, compact, manoeuvrable power chair which now incorporates Karma's patented 'S-Ergo' seating system. It is compact enough for indoor use but powerful enough for outdoors. The concept behind the design of the power chair was to make it as light as possible and convenient to transport. The Karma KP 10-2 Power Wheelchair can be taken apart quickly and easily into four manageable components. The heaviest part weighs just 24kg. The quick release battery box has a convenient charging point built into it, which allows the batteries to be charged away from the power chair. Karma KP 10.3 Power Wheelchair: Ergonomic seat system provides comfortable seating. Tool-free disassembled into 3 parts for traveling and transportation. Quick-release battery pack. Washable upholstery. Height adjustable and flip back armrest. 2-level adjustable back angle. Features: Frame: Breaks down into 4
wheelchairindia9

Choosing Correct Power wheel chair - 0 views

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    Power wheel chair is one type of wheel chairs which is also referred and known as Electric Power Wheel Chair or (EPW). An Power wheel chair is used to move such wheel chairs instead of pushing by some attendant or by hand rims. It also has navigational controls so that it can be moved to any desired direction. Power wheel chairs are suitable for those, who are weaker to move the manual wheel chair using the hand rims and also provides its users a level of comfort. The user can control its speed and direction by a joystick sort of control while sitting on the chair. There are many different types of Power wheel chair and finding the appropriate one will depend on each individual's medical condition. Wheelchairs can be manual or electrically powered. Manual wheelchairs can come in either a folding or rigid design. Rigid type wheelchairs tend to be lighter and more easily maneuvered and should be used by more active wheelchair users. Folding wheelchairs would be an excellent choice for individuals needing to use the wheelchair for travel on a frequent basis. Many people have disabilities that make it difficult to propel themselves in a manual wheelchair and in this situation an electrically powered wheelchair may prove more useful. Power chairs are little bit more complex and the user can control it with minimum effort. This kind of chair will give extraordinary maneuverability, stability and power and it is perfect for people who want more from their wheelchairs. Better Life Mobility Center offers various models, so sure that won't have problem to choose one that will suit completely. All the power chairs that offer are the result of the extensive research and designed with the user's needs in mind. Karma latest power standing wheelchair is now available in India. Power Wheelchairs For Sale - Increase freedom Stand up again improve independence and be find of body. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach f
wheelchairindia9

Choosing Correct Power wheel chair - 0 views

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    Power wheel chair is one type of wheel chairs which is also referred and known as Electric Power Wheel Chair or (EPW). An Power wheel chair is used to move such wheel chairs instead of pushing by some attendant or by hand rims. It also has navigational controls so that it can be moved to any desired direction. Power wheel chairs are suitable for those, who are weaker to move the manual wheel chair using the hand rims and also provides its users a level of comfort. The user can control its speed and direction by a joystick sort of control while sitting on the chair. There are many different types of Power wheel chair and finding the appropriate one will depend on each individual's medical condition. Wheelchairs can be manual or electrically powered. Manual wheelchairs can come in either a folding or rigid design. Rigid type wheelchairs tend to be lighter and more easily maneuvered and should be used by more active wheelchair users. Folding wheelchairs would be an excellent choice for individuals needing to use the wheelchair for travel on a frequent basis. Many people have disabilities that make it difficult to propel themselves in a manual wheelchair and in this situation an electrically powered wheelchair may prove more useful. Power chairs are little bit more complex and the user can control it with minimum effort. This kind of chair will give extraordinary maneuverability, stability and power and it is perfect for people who want more from their wheelchairs. Better Life Mobility Center offers various models, so sure that won't have problem to choose one that will suit completely. All the power chairs that offer are the result of the extensive research and designed with the user's needs in mind. Karma latest power standing wheelchair is now available in India. Power Wheelchairs For Sale - Increase freedom Stand up again improve independence and be find of body. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach f
Nathan Goodyear

Lower urinary tract symptoms improve with testosterone replacement therapy in men with ... - 0 views

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    Older men with low T found to have improved LUTS, based on prostate symptom score, with Testosterone therapy.  This flies in the face of concerns that Testosterone is a risk to the prostate.
Nathan Goodyear

[Testosterone replacement therapy and prostate cancer: the downfall of a paradigm?]. - ... - 0 views

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    In this time of evidence-based medicine, the prevailing therapy that Testosterone causes prostate cancer is devoid of evidence.
wheelchairindia9

Golden Motor Electric Wheelchair - 0 views

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    Powerchairs are generally four-wheeled or six-wheeled and non-folding, however some folding designs exist and other designs may have some ability to partially dismantle for transit. Four general styles of powerchair drive systems exist: front, centre or rear wheel drive and all-wheel drive. Powered wheels are typically somewhat larger than the trailing/castoring wheels, while castoring wheels are typically larger than the castors on a manual chair. Centre wheel drive powerchairs have castors at both front and rear for a six-wheel layout. Angel Wheelchair Electric standing wheelchair Standing up, driving function by power. Head and signal light (controlled by joystick). Adjustable headrest. Adjustable footplate. Detachable backrest Rigid steel framework W/liquid coating Flip-backward armrest Max speed: 9.15KM/H Front castor: 2.80/2.50-4 pneumatic castor (9") Rear wheels: 3.00-8 pneumatic tire (14") Available seat width: A (46 cm), D (42 cm) Max loading: A size: 135 kg Net weight w/o battery: 62.7 kg A powerchairs is a wheelchair that is propelled by means of an electric motor rather than manual power. Power wheelchairs are useful for those unable to propel a manual wheelchair or who may need to use a wheelchair for distances or over terrain which would be fatiguing in a manual wheelchair. They may also be used not just by people with 'traditional' mobility impairments, but also by people with cardiovascular and fatigue based condition. An powerwheelchair powers more than just chair. It gives the power to safely travel long distances on own. It empowers to navigate through home, backyard, school, workplace or local park. It gives power to do the things,want to do. It gives power. When accidents occur that leave permanent leg injuries, or as age sets in and joint pain becomes unbearable, the power chair acts as a gateway to continue living life to the fullest. The powerwheelchairs in our lineup are all battery powered, yet each device fills
wheelchairindia9

Choosing Correct Power wheel chair - 0 views

  •  
    Power wheel chair is one type of wheel chairs which is also referred and known as Electric Power Wheel Chair or (EPW). An Power wheel chair is used to move such wheel chairs instead of pushing by some attendant or by hand rims. It also has navigational controls so that it can be moved to any desired direction. Power wheel chairs are suitable for those, who are weaker to move the manual wheel chair using the hand rims and also provides its users a level of comfort. The user can control its speed and direction by a joystick sort of control while sitting on the chair. There are many different types of Power wheel chair and finding the appropriate one will depend on each individual's medical condition. Wheelchairs can be manual or electrically powered. Manual wheelchairs can come in either a folding or rigid design. Rigid type wheelchairs tend to be lighter and more easily maneuvered and should be used by more active wheelchair users. Folding wheelchairs would be an excellent choice for individuals needing to use the wheelchair for travel on a frequent basis. Many people have disabilities that make it difficult to propel themselves in a manual wheelchair and in this situation an electrically powered wheelchair may prove more useful. Power chairs are little bit more complex and the user can control it with minimum effort. This kind of chair will give extraordinary maneuverability, stability and power and it is perfect for people who want more from their wheelchairs. Better Life Mobility Center offers various models, so sure that won't have problem to choose one that will suit completely. All the power chairs that offer are the result of the extensive research and designed with the user's needs in mind. Karma latest power standing wheelchair is now available in India. Power Wheelchairs For Sale - Increase freedom Stand up again improve independence and be find of body. Karma KP 10.2 Power Wheelchair: Features: Seat, base & battery quickly detach f
wheelchairindia9

Folding Power Wheelchair - 0 views

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    GM LITE POWER WHEELCHAIR GM Lite Brushless Power Wheelchair with Batteries is a revolutionary light weight power wheelchair using brushless motor. It is the most economic power wheelchair without sacrificing safety & durability. The wheelchair promotes pressure redistribution, reduces downward sliding and helps maintain good posture. Specifications: 10 times longer life Lightest - 23 kg 5 year long life, safe LiFePO4 battery (10ah) High efficiency brushless hub motor 5 seconds folding and unfolding Easy to carry Load : 120 kg Speed : 8km/hr Range: 15 km Slope : 12% 24V180W brushless 8-inch gear hub motor
Nathan Goodyear

Testosterone and Abnormal Glucose Metabolism in an Inner-City Cohort - 0 views

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    This study of inner city men found low T associated with methadone use.  Narcotics are a known risk factor for low T.  The free T was calculated from serum.  This equilibrium dialysis is based on too many variables.  Look at the studies on equilibrium dialysis.  This study also found calculated free T was not associated with insulin resistance.  However, insulin resistance is a peripheral tissue dysfunction not a serum dysfunction.  So, a calculated free T (not reality) in the serum shows me nothing of the peripheral activity.  For example, inflammation has been shown to increase aromatase activity in the prostate tissue only.  The thinking in the conclusions of so many of these studies is soooo flawed.
Nathan Goodyear

JAMA Network | JAMA Surgery | Three-Year Outcomes of Bariatric Surgery vs Lif... - 0 views

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    new study finds that bariatric surgery outperforms lifestyle interventions in improving glucose control in obese individuals.  On the surface this seems interesting, but the lifestyle interventions were based on the Diabetes Prevention program.  The diabetes prevention program doesn't do well in glucose control in any clients (see increasing diabetes rates), so it should be no surprise that bariatric surgery outperforms a program that doesn't work
Nathan Goodyear

Gamma-linolenic acid induces apoptosis in B-chroni... [Leuk Lymphoma. 2001] - PubMed re... - 0 views

  • n the presence of GLA 5 microg/ml and dexamethasone the degree of apoptosis was 86%
  • These results demonstrate that GLA induces apoptosis in B-CLL B- and T-cells cells in vitro and that they are more susceptible to GLA-induced apoptosis than normal peripheral blood B- and T-cells.
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    GLA, omega-6 found in plant based oils,  kills 42% of leukemia cells; with dexamethasone, the kill rate increases to 86%
Nathan Goodyear

Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies: Fact Sheet - 0 views

  • Recent studies indicate an average of 17 years is needed before new knowledge generated through research, such as randomized clinical trials, is incorporated into widespread clinical practice
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    Doctors practice 17 years behind current knowledge base
Nathan Goodyear

Evidence that calcium supplements reduce fracture ... [Clin J Am Soc Nephrol. 2010] - P... - 0 views

  • Until well designed, well executed, and well analyzed studies demonstrate a net benefit in morbidity, mortality, and cost, recommendations supporting the widespread use of calcium supplementation remain belief-based and not evidence-based
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    contrary to current thought, well designed studies that support Calcium supplementation to reduce fracture risk does not exist
Nathan Goodyear

American Journal of Hypertension - Treatment of Hypertension: A Failing Report Card - 0 views

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    hypertension has different causes and needs to be treated based on the underlying pathophysiology, not a pin the tail on the donkey approach
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