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IV Vitamin C improves endothelial vasodilation in essential hypertension.  The Vitamin C reduces the oxygen free radicals which allowed eNOS to increase NO production.  Two take homes: oxygen free radicals may be responsible for the endothelial dysfunction that leads to essential hypertension and vitamin C, particularly IV, can be used to counter this process.  Other studies have shown IV vitamin C to be anti-hypertensive in its action.

common anti-hypertensive medication shown to reduce testosterone levles

upregulated RAS associated with stimulated breast cancer growth.  Anti-hypertensive therapy not only can it impact the cancer growth potential but also can augment chemotherapy.

testosterone therapy has tremendous cardiovascular benefit in men with low T.  The key here is physiologic replacement of Testosterone.  Testosterone is a vasodilator and anti-inflammatory agent in men with low T.  Testosterone therapy improves cardiac function in those with DHF and angina.  Testosterone is found to be a Ca++ channel blocker--anyone say hypertension treatment?

treatment with anti-angiogenesis meds often are associated with the SE of HTN; What is interesting about this is that this is associated with improved survival.

There is just no reason to take SSRIs during pregnancy.  SSRIs increase risk of miscarriage, birth defects, preterm birth, newborn behavior problems, pulmonary hypertension...All women considering pregnancy should removed, yet SSRIs are prescribed as if they are candy.

prazosin promotes apoptosis of gliobastoma-initiating cells in mouse model via Akt pathway.