Neuroprotective Sirtuin ratio reversed by ApoE4 - 0 views
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Nathan Goodyear on 23 Oct 13ApoE4 allele is known to increase Alzheimer's disease by 10 fold. One mechanism is through a lowering of SirT1 and an increase in the SirT1:SirT2 ratio. This SirT1 is the target of resveratrol in red wine.