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Nathan Goodyear

Long‐acting octreotide versus placebo for treatment of advanced HCC: A random... - 0 views

aasldpubs.onlinelibrary.wiley.com/...hep.21468

octreotide GH growth hormone cancer liver cancer

shared by Nathan Goodyear on 09 Jul 18 - No Cached
  • Nathan Goodyear on 09 Jul 18
     
    Octreotide, GH inhibitor, no better than placebo in liver cancer.
Nathan Goodyear

Clinical Pharmacodynamic Effects of the Growth Hormone Receptor Antagonist Pegvisomant:... - 0 views

clincancerres.aacrjournals.org/...1000

cancer GH growth hormone

shared by Nathan Goodyear on 12 Aug 19 - No Cached
  • Nathan Goodyear on 12 Aug 19
     
    Pegvisomant shown to provide more GH, IGF-1 suppression compared to octreotide. The doses used were 40, 60, and 80 mg SQ. The higher dose resulted in the greatest suppression.
Nathan Goodyear

The Cardiovascular Risk of Adult GH Deficiency (GHD) Improved after GH Replacement and ... - 0 views

jcem.endojournals.org/...1088.short

HGH IGF-1 deficiency human growth hormone CVD cardiac heart cardiovascular

shared by Nathan Goodyear on 12 Nov 12 - No Cached
  • Nathan Goodyear on 12 Nov 12
     
    in those adults with HGH deficiency, HGH replacement found to improve lipids, IGF-1, and cardiac function.
Nathan Goodyear

THERAPY OF ENDOCRINE DISEASE: GH therapy in adult GH deficiency: A review of treatment ... - 0 views

www.eje-online.org/...R55.full

HGH human growth hormone IGF-1 adults aging hormone hormones therapy deficiency

shared by Nathan Goodyear on 05 Mar 13 - No Cached
  • Nathan Goodyear on 05 Mar 13
     
    Great review on HGH diagnosis, treatment, and follow up in adult onset HGH deficiency.  
Nathan Goodyear

Does growth hormone cause cancer? [Clin Endocrinol (Oxf). 2006] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...16430706

human growth hormone HGH IGF-1 cancer CA

shared by Nathan Goodyear on 06 Jul 12 - No Cached
  • Nathan Goodyear on 06 Jul 12
     
    epidemiological studies are the only thing that has linked GH to cancer risk; review of human studies of children and adults finds no increase risk of cancer associated with HGH therapy.
Nathan Goodyear

Growth hormone treatment and risk of recurr... [Childs Nerv Syst. 2009] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...19142625

growth hormone growth cancer hormones

shared by Nathan Goodyear on 09 Jul 12 - No Cached
  • Nathan Goodyear on 09 Jul 12
     
    Growth hormone did not show to increase brain tumor progression or recurrence; this dispels the myth that GH causes/progresses cancer.
Nathan Goodyear

Increased adiposity and insulin correlates with the progressive suppression of pulsatil... - 0 views

joe.endocrinology-journals.org/...233.abstract

growth hormone GH insulin obesity overweight

shared by Nathan Goodyear on 24 Jul 13 - No Cached
  • Nathan Goodyear on 24 Jul 13
     
    Growth hormone inversely associated with weight and insulin levels.
Nathan Goodyear

Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men wi... - 0 views

www.ncbi.nlm.nih.gov/...8923860

muscle loss Muscle mass Testosterone hormones AIDS AWS

shared by Nathan Goodyear on 15 Jun 15 - No Cached
  • Nathan Goodyear on 15 Jun 15
     
    Only abstract available here, but muscle loss associated with low Testosterone in men with AWS.
Nathan Goodyear

A potential role of endogenous progesterone in mod... [Clin Endocrinol (Oxf). 2009] - P... - 0 views

www.ncbi.nlm.nih.gov/...19222493

progesterone HGH human growth hormone

shared by Nathan Goodyear on 20 May 11 - No Cached
  • These data also suggest that endogenous progesterone could play a modulation role on pituitary hormone secretion, stimulating GH and PRL release and enhancing the inhibitory action of sleep on TSH secretion.
  • normally cycling young women, daytime GH and PRL secretions are increased in luteal phase
  • Nathan Goodyear on 20 May 11
     
    normal luteal progesterone production stimulate HGH release
Nathan Goodyear

Evidence for an Inhibitory Effect of Physiological Levels of Insulin on the Growth Horm... - 0 views

jcem.endojournals.org/...2239.short

insulin resistance HGH weight gain loss

shared by Nathan Goodyear on 29 Jul 11 - No Cached
  • Nathan Goodyear on 29 Jul 11
     
    Insulin inhibits HGH production.  Key component of weight gain in our society today, with insulin resistance at an all time high.
Nathan Goodyear

Growth hormone treatment in adults with Prader-Wil... [Endocrine. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22081257

growth hormone growth hormone hormones Prader-Willi Syndrome fat

shared by Nathan Goodyear on 03 Aug 14 - No Cached
  • Nathan Goodyear on 03 Aug 14
     
    Thought GH in those with Prader-Willi Syndrome did not see an improvement in lipid and glucose metabolism, lean body mass increased and fat mass decreased.
Nathan Goodyear

Growth hormone is permissive for neoplastic colon growth - 0 views

www.pnas.org/...E3250

colorectal cancer HGH colon cancer growth hormone

shared by Nathan Goodyear on 14 Aug 19 - No Cached
  • Nathan Goodyear on 14 Aug 19
     
    Elevated GH levels favor carcinogenesis and spread of colorectal cancer.
Nathan Goodyear

Role of the growth hormone-IGF-1 axis in cancer: Expert Review of Endocrinology & Metab... - 0 views

www.tandfonline.com/...eem.10.73

cancer growth hormone HGH

shared by Nathan Goodyear on 14 Aug 19 - No Cached
  • Nathan Goodyear on 14 Aug 19
     
    Great read on the different mechanisms by which GH promotes carcinogenesis and growth via STATs, P13K/Akt, mTOR, IGF-1...
Nathan Goodyear

Thieme E-Journals - International Journal of Sports Medicine / Abstract - 0 views

www.thieme-connect.de/...DOI

exercise training sports sports medicine resistance training weight lifting

shared by Nathan Goodyear on 30 Nov 17 - No Cached
  • Nathan Goodyear on 30 Nov 17
     
    Only abstract available here: compound resistance treaining in highly trained young men found to increase GH and Testosterone over isolation exercises. Those that trained > 2 years had significnt increase in Testosterone pre/post exercise compared to no statistical change in those traing < 2 years.
Nathan Goodyear

Testosterone and Estradiol Regulate Free Insulin-Like Growth Factor I (IGF-I), IGF Bind... - 0 views

jcem.endojournals.org/...2941.full

IGF-1 testosterone Estradiol growth hormone hormones HGH GH IGFBP-1

shared by Nathan Goodyear on 12 Nov 12 - No Cached
  • Nathan Goodyear on 12 Nov 12
     
    testosterone and Estradiol effect IGF-1 levels.  This small study looked at 8 men and 8 postmenopausal women.  Findings:  low testosterone and high estradiol decrease IGF-1 availability.   Estradiol in postmenopausal women will result in a decrease in IGF-1 through an elevation of IGFBP-1.  In men, testosterone replacement stimulates increased HGH secretion and resultant IGF-1 secretion
Nathan Goodyear

Ghrelin-Induced Food Intake Is Mediated via the Orexin Pathway - 0 views

endo.endojournals.org/...1506.long

ghrelin orexin orexins appetite

shared by Nathan Goodyear on 28 May 13 - No Cached
  • Ghrelin, a peptide produced in the stomach and hypothalamus, stimulates feeding and GH secretion
  • Centrally administered ghrelin exerts an orexigenic activity through the neuropeptide Y (NPY)
  • though ghrelin is predominantly produced in endocrine cells of the stomach (17, 18), it is also synthesized in the hypothalamic arcuate nucleus (1, 19), a critical region for feeding
  • Nathan Goodyear on 28 May 13
     
    ghrelin stimulates feeding through orexin signaling.
Nathan Goodyear

Administration route-dependent effects of estrogens on IGF-I levels during fixed GH rep... - 0 views

eje-online.org/...709.long

oral estrogen therapy oral estrogen therapy IGF-1 human growth hormone HGH hormone hormones women

shared by Nathan Goodyear on 19 Feb 13 - No Cached
  • Nathan Goodyear on 19 Feb 13
     
    oral estrogen therapy decreased IGF-1 concentrations in those women taking growth hormone, requiring high dosing of HGH versus that in women using estrogen through a transdermal approach.
Nathan Goodyear

Editorial: Diagnosis of GH Deficiency in Adults--How good do the criteria need to be? - 0 views

jcem.endojournals.org/...473.full.pdf

growth hormone deficiency growth hormone GHD hormone hormones

shared by Nathan Goodyear on 09 Jul 12 - No Cached
  • Nathan Goodyear on 09 Jul 12
     
    Growth hormone deficiency is safe and effective in those adults with GHD.
Nathan Goodyear

Effects of Testosterone and Growth Hormone on the Structural and Mechanical Properties ... - 0 views

press.endocrine.org/...jc.2013-3665

Testosterone bone men male hormones growth hormone GH low T

shared by Nathan Goodyear on 16 Apr 14 - No Cached
  • Nathan Goodyear on 16 Apr 14
     
    IN men with low Testosterone, Testosterone therapy improved trabecular bone, but not cortical bone.  Growth hormone provided no additional benefit.  This study looked at men with panhypopituitarism.
Nathan Goodyear

Sensitivity and Specificity of Six Tests for the Diagnosis of Adult GH Deficiency: The ... - 0 views

press.endocrine.org/...jcem.87.5.8509

HGH deficiency low human growth hormone test

shared by Nathan Goodyear on 02 Apr 14 - No Cached
  • Nathan Goodyear on 02 Apr 14
     
    review of 6 diagnostic test methods for adult onset HGH deficiency.
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