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wheelchairindia9

KM 7501 Wheelchair - 0 views

disabilityproduct.in/...Karma-Wheelchair-KM-7501

New Ergonomic Wheelchair Seats Allow for Greater User Movement correct height for workstation different sitting heights and postures allowing posture changes S shape of the spine when sitting machine washable cushion foldable and easy to store

shared by wheelchairindia9 on 02 Sep 15 - No Cached
  • wheelchairindia9 on 02 Sep 15
     
    Ergonomic Wheelchair often spend a lot of time leaning on armrests or a table exactly because they are not being supported with good posture in their chairs. This is a matter of seat angle and back angle, adjusting them according to body shape and degree of upper body balance. Poor seating makes slump, trying to get stable. The optimal posture is more upright, allowing spine to support. Ergonomic chairs are designed to confirm to a person's physical dimensions, allowing them to sit naturally and comfortably for long periods of time, while reducing the risk of pressure ulcers. Ergonomic system (Intelligent s-shaped ergonomic seating) provides efficient pressure relief by spreading weight over a greater area, at the same time provides stabilization and reduced sliding. With their lightweight frames and seats designed to reduce or prevent pressure points, ergonomic wheelchairs provide a comfortable option for mobility impaired users who have the upper body strength to propel themselves, or a caregiver strong enough to do so. Karma S Ergo 115 Wheelchair: This model features our S-Shape Seating System and is our number one best seller for many reasons. At a mere 11.3 kg in weight with detachable foot rest and many features such as removable machine washable and dry-able cushions treated by AEIGIS treated anti-microbial coated seating system. Karma S-Ergo 115 Wheelchair Features: Ergonomic Handrims & S-Shape Ergonomic Seating System Fixed armrest w/ wider concave armpads Swing In & Away Footrests Backrest Pouch attached to the upholstery 24" flat free polyurethane tires, high tread, flat free wheels Seat width: 16"x17" or 18"x17" or 20"x 17" Silver 1/4" Aegis Anti-Bacterial Upholstery, washable Folding backrest / folding seat for easy traveling "Tube-in Center" foot-plate, assures better side leg support High strength, starting weight at only 11.3 kg. (w/o footrests) 7×1" Polyurethane front casters Upholstery: Black breathable mesh bottom & t
wheelchairindia9

Karma Km 5000 Wheelchair - 0 views

disabilityproduct.in/...a-Reclining-Wheelchair-KM-5000

Disability Seating And Tilt-In-Space Wheelchair adjustable seat height and depth systems provide added comfort neck and trunk a much-needed break wheelchair provides a sole pivot point movable armrest and elevating footrest

shared by wheelchairindia9 on 21 Aug 15 - No Cached
  • wheelchairindia9 on 21 Aug 15
     
    Karma Reclining Wheelchair KM 5000 The karma reclining wheelchair km-5000 Transport Wheelchair is an ultra lightweight folding aluminum reclining wheelchair. With full length padded armrests, an adjustable height head pillow, and more this wheelchair has added comfort for any user. This chair also features swing-away elevating footrests and adjustable length leg supports and footplates. With a weight of 33 Lbs this chair can be transported with ease. Karma Reclining Wheelchair KM 5000 Features Folding 6061 T-6 Aircraft-grade aluminum frame in black powder coat finish Backrest Reclines 90°~163° and includes anti-tippers Full length padded detachable armrests with side panels Swing-away detachable elevating footrests Adjustable length leg supports & footplates Adjustable-height head pillow 14" Mag wheels with flat free polyurethane tires 7" x 1" Flat free front polyurethane casters Adjustable toggle wheel locks High-grade flame retardant, breathable nylon upholstery Limited lifetime warranty on frames and cross-braces, one year on parts One of only two lightweight recliners available in the USA Also Available in Large Manual Rear Wheel option, (KM- 5000F), please call for more info Frame Color: Silver WARRANTY 1 Year Karma Reclining Wheelchair KM 5000 Measurements Seat Width 18 inch. Seat Depth 18 inch. Seat Height 20 inch. Back Height 33 inch. Overall Height 51 inch. Overall Open Width 25 inch., 27 inch., 29 inch., 31 inch. Overall Length 39 inch. Weight Without Riggings 33 lb., 34 lb. Weight Cap 250 lb., 300 lb., 350 lb. Shipping Dimensions 39? L x 30? H x 14? W
Nathan Goodyear

Hypovitaminosis D in Patients Scheduled to Undergo Orthopaedic Surgery: A Single-Center... - 0 views

www.ejbjs.org/...2300

vitamin D deficiency

shared by Nathan Goodyear on 21 Jan 11 - No Cached
  • Given the importance of vitamin D in musculoskeletal health, such low levels may negatively impact patient outcomes.
  • Nathan Goodyear on 21 Jan 11
     
    Vitamin D deficiency slows orthopedic surgery healing
Nathan Goodyear

Revealing Estrogen's Secret Role In Obesity - 0 views

www.sciencedaily.com/...070820145348.htm

estrogen obesity

shared by Nathan Goodyear on 07 Jun 11 - No Cached
  • researchers showed how estrogen receptors located in the hypothalamus serve as a master switch to control food intake, energy expenditure and body fat distribution.
  • This research seems to support a link between estrogen and regulation of obesity
  • ventromedial nucleus or VMN, is a key center for energy regulation.
  • ...2 more annotations...
  • When estrogen levels in the VMN dipped, the animals' metabolic rate and energy levels also plummeted
  • The findings suggested that the ER-alpha in this region plays an essential role in controlling energy balance, body fat distribution and normal body weight.
  • Nathan Goodyear on 07 Jun 11
     
    estrogen plays role in obesity in menopausal women.
Nathan Goodyear

Antidepressants Linked to Thicker Arteries | Woodruff Health Sciences Center | Emory Un... - 0 views

shared.web.emory.edu/...inked-to-thicker-arteries.html

antidepressants serotonin

shared by Nathan Goodyear on 06 Apr 11 - No Cached
  • “I think we have to keep an open mind about the effects of antidepressants on neurochemicals like serotonin in places outside the brain
  • Nathan Goodyear on 06 Apr 11
     
    antidepressants linked to increased arterial thickness; We must think about the body from a dynamic perspective, not a linear one
Nathan Goodyear

Obese Americans now outweigh the merely overweight | Reuters - 0 views

www.reuters.com/...sity-usa-idUSTRE50863H20090109

obese overweight americans statistics obesity weight loss

shared by Nathan Goodyear on 15 Apr 11 - No Cached
  • Numbers posted by the National Center for Health Statistics show that more than 34 percent of Americans are obese, compared to 32.7 percent who are overweight. It said just under 6 percent are "extremely" obese.
  • More than one-third of adults, or over 72 million people, were obese in 2005-2006, the NCHS said in its report
  • In May, the CDC reported that 32 percent of U.S. children fit the definition of being overweight, 16 percent were obese and 11 percent were extremely obese.
  • Nathan Goodyear on 15 Apr 11
     
    obesity in America
Nathan Goodyear

Health Information - Grande Dunes Surgery Center - 0 views

grandedunessurgerycenter.com/...index.dot

ALCAT food allergies sensitivities

shared by Nathan Goodyear on 02 May 11 - No Cached
  • Nathan Goodyear on 02 May 11
     
    Food Allergies and Sensitivities
Nathan Goodyear

Gluten Sensitivity and Celiac Disease - 0 views

www.umm.edu/...sensitivity-celiac-disease.htm

gluten sensitivity disease

shared by Nathan Goodyear on 03 May 11 - No Cached
  • cientists at the University of Maryland School of Medicine’s Center for Celiac Research have proven that gluten sensitivity is different from celiac disease at the molecular level and in the response it elicits from the immune system
  • Nathan Goodyear on 03 May 11
     
    Gluten sensitivity different than celiac disease proven
Nathan Goodyear

The prevalence of hypogonadism in diabetic men in Isfahan Endocrine and Metabolism Rese... - 0 views

www.ncbi.nlm.nih.gov/...PMC3685773

low T low Testosterone Diabetes men Iran low testosterone T hormone hormones

shared by Nathan Goodyear on 02 Jul 13 - No Cached
  • Nathan Goodyear on 02 Jul 13
     
    Incidence of Low Testosterone very high in men with Diabetes in Iran.  This was the case whether Total Testosterone, calculated free Testosterone, calculated Biologic Testosterone, or SHBG was used.
xshop69

Alat Pembesar Payudara | Jual Vacum Pembesar Payudara - 0 views

www.galeri-obat.com/alat-pembesar-payudara

jual alat pembesar payudara vakum permanen

shared by xshop69 on 28 Jan 15 - No Cached
  • xshop69 on 28 Jan 15
     
    Contact Person : Hotline : 0812 262 44 333 Sms Center : 0812 262 44 333 PIN BBM : 24CF A780 Alat Pembesar Payudara - Vacum Pembesar Payudara - Alat Pembesar Payudara Alami - Cara Cepat Membesarkan Susu - Tabung Sport - Jual Vakum Payudara Wanita - Vakum Pembesar Payudara Wanita.
Nathan Goodyear

Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypo... - 0 views

press.endocrine.org/...jcem.81.10.8855787

Testosterone low T low Testosterone hypogonadism muscle mass protein muscle metabolism men male hormone hormones

shared by Nathan Goodyear on 06 Mar 15 - No Cached
  • Nathan Goodyear on 06 Mar 15
     
    Testosterone therapy in men with low T is associated with an increase in protein synthesis and thus an increase in muscle mass.
Nathan Goodyear

Quality of diet and mortality among Japanese men and women: Japan Public Health Center ... - 0 views

www.bmj.com/bmj.i1209

lifestyle nutrition mortality health diet

shared by Nathan Goodyear on 05 Apr 16 - No Cached
  • Nathan Goodyear on 05 Apr 16
     
    Healthy lifestyle choices reduce mortality.
Nathan Goodyear

Multiple Myeloma Tumor Cells are Selectively Killed by Pharmacologically-dosed Ascorbic... - 0 views

www.ebiomedicine.com/...fulltext

multiple myeloma vitamin C IV vitamin C smoldering myeloma cancer

shared by Nathan Goodyear on 25 Sep 17 - No Cached
  • Recent reports indicate that a certain ROS concentration is required for high-dose vitamin C to induce cytotoxicity in cancer cells.
  • The generation of ascorbyl- and H2O2 radicals by PAA increases ROS stress in cancer cells
  • In this study, we report that PAA is efficacious in killing MM cells in vitro and in vivo models, which generated levels of 20–40 mM ascorbate and 500 nM ascorbyl radicals after intraperitoneal administration of 4 g ascorbate per kilogram of body weight (Chen et al., 2008Chen et al., 2008), in xenograft MM mice
  • ...33 more annotations...
  • These data suggest that PAA may show a therapeutic advantage to blood cancers vs solid tumors because of the communication between tumor cells and blood plasma
  • These results strongly suggest that the mechanism of PAA killing of MM cells is indeed iron-dependent
  • These results suggest that PAA administration in SMM may be able to prevent progression to symtomatic MM
  • A recent study by Yun and colleagues demonstrated that vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH, but spares normal cells
  • RAS family genes show the most frequent mutations in MM. KRAS, NRAS and BRAF are mutated in 22%, 20% and 7% of MM samples
  • the disease stage rather than the mutation of RAS and/or BRAF is the major predictive factor for PAA sensitivity in MM treatment
  • Other molecular mechanisms including ATP depletion and ATM-AMPK signaling have been reported to explain PAA-induced cell death
  • our pilot study also suggested that PAA could overcome drug resistance to bortezomib in MM cells
  • Our findings complement reported studies and further address the mechanism of action using clinical samples in which we observed that PAA killed tumor cells with high iron content, suggesting that iron might be the initiator of PAA cytotoxicity
  • combination of PAA with standard therapeutic drugs, such as melphalan, may significantly reduce the dose of melphalan needed
  • Combined treatment of reduced dose melphalan with PAA achieved a significantly longer progression-free survival than the same dose of melphalan alone.
  • These data also suggest that the bone marrow suppression induced by high-dose melphalan can be ameliorated by the combination of PAA with lower dose of melphalan because of the lack of toxicity of PAA on normal cells with low iron content.
  • if creatinine clearance is <30 mL/min, high dose ascorbic acid should be not administrated.
  • In MM preclinical and clinical studies, ascorbate was used as an adjunct drug and showed controversial results (Harvey et al., 2009, Perrone et al., 2009, Held et al., 2013, Sharma et al., 2012, Nakano et al., 2011, Takahashi, 2010, Sharma et al., 2009, Qazilbash et al., 2008). However, none of these tests used pharmacological doses of ascorbate and intravenous administration
  • Multiple myeloma (MM) is a plasma cell neoplasm.
  • Cameron and Pauling reported that high doses of vitamin C increased survival of patients with cancer
  • pharmacologically dosed ascorbic acid (PAA) 50–100 g (Chen et al., 2008, Padayatty et al., 2004, Hoffer et al., 2008, Padayatty et al., 2006, Welsh et al., 2013), administered intravenously, has potent anti-cancer activity and its role as anti-cancer therapy is being studied at the University of Iowa and in other centers
  • In the presence of catalytic metal ions like iron, PAA administered intravenously exerts pro-oxidant effects leading to the formation of highly reactive oxygen species (ROS), resulting in cell death
  • the labile iron pool (LIP) is significantly elevated in MM cells
  • The survival of CD138+ cells in vitro was significantly decreased following PAA treatment in all 9 MM
  • In contrast, no significant change of cell viability was observed in CD138− BM cells from the same patients
  • The same effect of PAA was also observed in the SMM patients
  • no response to PAA was detected in CD138+ cells from the 2 MGUS patients
  • the combination of melphalan plus PAA showed greater tumor burden reduction than each drug alone, suggesting a synergistic activity between these two drugs
  • Both catalase and NAC protect cells from oxidative damage
  • cells pretreated with NAC and catalase became resistant to PAA even at high doses
  • adding deferoxamine (DFO), an iron chelator, to OCI-MY5 cells before PAA treatment was also sufficient to prevent PAA-induced cellular death
  • iron is essential for PAA to achieve its anti-cancer activity
  • PAA induced early necrosis (Fig. 3Fig. 3A, 60 min) followed by late apoptosis
  • results further indicated that PAA induced mitochondria-mediated apoptosis
  • PAA by reacting with LIP and generating ROS induces mitochondria-mediated apoptosis in which AIF1 cleavage is important for cell death.
  • ROS and H2O2 are well known factors mediating PAA-induced cancer cell death
  • PAA was sensitive to all 9 MMs and 2 SMMs
  • Nathan Goodyear on 25 Sep 17
     
    animal study finds high-dose, pharmacologic vitamin C found to kill multiple myeloma cells via pro-oxidant effect found in similar studies in dealing with different cancers.
FMS Dental Hospital

Best Cosmetic Dentist, Smile Designing, Dental Porcelain Veneers Hyderabad India | FMS ... - 0 views

www.fmsdental.com/cosmetic-dentistry-home

Best Dental Cosmetic Clinic in India

shared by FMS Dental Hospital on 27 Mar 18 - No Cached
  • FMS Dental Hospital on 27 Mar 18
     
    Dedicated Team of cosmetic dentists and use of most advanced Digital Smile Designing technology has revolutionized cosmetic dentistry at FMS. So uncover your flawed smile, and embrace the new horizons of beauty . With over 2 decades of experience in the field of Dentistry, FMS Dental Hospital is today the recognized center for, COSMETIC DENTISTRY, WITH THE BEST COSMETIC DENTIST, SMILE DESIGNING, DENTAL PORCELAIN VENEERS IN HYDERABAD.
FMS Dental Hospital

Best Cosmetic Dental Clinic in India - 0 views

FMS DENTAL is one of the top dental clinics in Hyderabad, India and 5th best dental center in the world (GCR Rating), with multi-specialty practice, in-patient facility and 24 hr. emergency dental ...

Best Cosmetic Dental Clinic in India Dentist

started by FMS Dental Hospital on 27 Mar 18 no follow-up yet
Nathan Goodyear

Plasma 25-hydroxyvitamin D concentration and subsequent risk of total and site specific... - 0 views

www.bmj.com/bmj.k671

vitamin D cancer

shared by Nathan Goodyear on 15 Mar 18 - No Cached
  • Nathan Goodyear on 15 Mar 18
     
    New Study from BMJ finds that higher vitamin D levels are associated with a decreased relative risk for total cancer.  The most significant inverse association was found with risk of liver cancer. The study divided the vitamin D levels into quartiles.
Nathan Goodyear

Hypertension as a biomarker in patients with recurrent glioblastoma treated with antian... - 0 views

www.ncbi.nlm.nih.gov/...23075631

hypertension glioblastoma multiforme Glioblastoma

shared by Nathan Goodyear on 14 May 18 - No Cached
  • Nathan Goodyear on 14 May 18
     
    treatment with anti-angiogenesis meds often are associated with the SE of HTN; What is interesting about this is that this is associated with improved survival.
Nathan Goodyear

Late Disseminated Lyme Disease: Associated Pathology and Spirochete Persistence Post-Tr... - 0 views

ajp.amjpathol.org/...fulltext

Lyme Lyme disease borrelia burgdorferi

shared by Nathan Goodyear on 14 Dec 17 - No Cached
  • In this study, we have demonstrated microscopic pathology ranging from minimal to moderate in multiple different tissues previously reported to be involved with LD, including the nervous system (central and peripheral), heart, skeletal muscle, joint-associated tissues, and urinary bladder 12 to 13 months following tick-inoculation of rhesus macaques by Bb strain B31
  • Based on histomorphology, inflammation consisted predominantly of lymphocytes and plasma cells, with rare scattered histiocytes
  • in rare instances, morphologically intact spirochetes were observed in inflamed brain and heart tissue sections from doxycycline-treated animals
  • ...41 more annotations...
  • colocalization of the Bb 23S rRNA probe was not observed in any of the sections of experimental inoculated animals shown to harbor rare persistent spirochetes (Supplemental Figure S1). Previous in vitro work has shown large decreases in Bb rRNA levels when in a stationary phase of growth despite the majority of spirochetes remaining viable
  • The possibility that the spirochetes were intact but dead also exists, though this may be unlikely given the precedence for viable but non-cultivable B. burgdorferi post-treatment
  • The doxycycline dose utilized in this study (5mg/kg) was based on a previous pharmacokinetic analysis of oral doxycycline in rhesus macaques proven to be comparable to levels achieved in humans and was meant to mimic treatment of disseminated LD
  • In addition to the brain of two treated animals, rare morphologically intact spirochetes immunoreactive to OspA were observed in the heart of one treated animal
  • Although we did not measure the doxycycline levels in the cerebrospinal fluid, they have been found to be 12% to 15% of the amount measured in serum
  • We and others have demonstrated the development of a drug-tolerant persister population when B. burgdorferi are treated with antibiotics in vitro
  • The adoption of a dormant or slow-growing phenotype likely allows the spirochetes to survive and re-grow following removal of antibiotic
  • The basic premise that antibiotic tolerance may be an adaptation of the sophisticated stringent response required for the enzootic cycle by the spirochetes is described in a recent review as well
  • Although current IDSA guidelines recommend intravenous ceftriaxone (2g daily for 30 days) over oral doxycycline for treatment of neuroborreliosis, a randomized clinical trial failed to show any enhanced efficacy of I.V. penicillin G to oral doxycycline for treatment of Lyme neuroborreliosis (no treatment failures were reported in this study of 54 patients).
  • we can speculate that the minimal to moderate inflammation that was observed, especially within the CNS and PNS can, in part, explain the breadth of symptoms experienced by late stage Lyme disease patients, such as cognitive impairment and neuralgia.
  • Erythema migrans, the clinical hallmark of early localized Lyme disease, was observed in one of the rhesus macaques from this study.
  • In 2014, a trailblazing study in mice demonstrated a dramatic decline in B. burgdorferi DNA in the tissues for up to eight months after antibiotic treatment followed by the resurgence of B. burgdorferi growth 12 months after treatment
  • This study provides evidence that the slow-growing spirochetes which persist after treatment, but are not cultivable in standard growth media may remain viable.
  • The first well-documented indication of Lyme disease (LD) in the United States occurred in the early 1970s
  • Lyme, Connecticut.
  • Lyme disease is now known to be caused by multiple closely related genospecies classified within the Bb sensu lato complex, representing the most common tick-borne human disease in the Northern Hemisphere
  • approximately 30,000 physician-reported cases occur annually in the United States, the annual incidence has been estimated to be 10-fold higher by the Centers for Disease Control and Prevention.6
  • Current antibiotic therapy guidelines outlined by the Infectious Disease Society of America (IDSA) are successful in the treatment of LD for the majority of LD patients, especially when administered early in disease immediately following identification of erythema migrans (EM)
  • ‘post-treatment Lyme disease syndrome’ (PTLDS)
  • host-adapted spirochetes that persist in the tissues, probably in small numbers, inaccessible or impervious to antibiotic
  • inflammatory responses to residual antigens from dead organisms
  • residual tissue damage following pathogen clearance;
  • autoimmune responses, possibly elicited by antigenic mimicry
  • Experimental studies on immunocompetent mice, dogs, and rhesus macaques have provided evidence for the persistence of Bb spirochetes subsequent to antibiotic treatment in the form of residual spirochetes detected within tissue by IFA and PCR, and recovered by xenodiagnoses
  • Ten male rhesus macaques
  • half (five) of the NHP received antibiotic treatment, consisting of 5 mg/kg oral doxycycline twice per day.
  • Minimal and focal lymphoplasmacytic inflammation
  • inflammation was observed in the leptomeninges overlying a section of temporal cerebral cortex
  • Minimal localized lymphoplasmacytic choroiditis
  • Peripheral nerves contained minimal to moderate lymphoplasmacytic inflammation with a predilection for collagen-rich epineurium and perivascular spaces
  • Inflammation was observed in 56% (5/9) of the NHPs irrespective of treatment group
  • For all animals, inflammation was reserved to perineural tissue
  • The treatment lasted 28 days
  • Minimal to mild lymphoplasmacytic inflammation of either the myocardial interstitium (Figure 2Figure 2A), pericardium (Figure 2Figure 2B), or combination therein was observed in 60% of NHPs
  • A single morphologically intact spirochete, as indicated by positive red immunofluorescence (Figure 2Figure 2C), was observed in the myocardium of one treated animal
  • mild, multifocal lymphoplasmacytic inflammation was observed in one doxycycline-treated animal
  • three animals exhibited minimal to mild lymphoplasmacytic inflammation affecting joint-associated structures
  • 10% to -20% of human patients treated
  • Multiple randomized placebo-controlled studies which evaluated sustained antimicrobial therapy concluded that there is no benefit in alleviating patients’ symptoms and indicated that long-term antibiotic therapy may even be detrimental to patients due to potential associated complications (ie, catheter infection and/or clostridial colitis)
  • and the rapid clearance of dead spirochetes in a murine model
  • higher doses may be needed to combat neuroborreliosis
  • Nathan Goodyear on 14 Dec 17
     
    persistent borrelia burgdorferia were found in the brain (2) and the heart (1) up to 13 months post standard antibiotic treatment suggesting borrelia burdorferia, the cause of Lyme, can persist in a chronic, persistant state poste acute treatment.
in-sync

Best Child Development Center in Hyderabad | Speech therapy in Hyderabad | In-Sync - 0 views

in-sync.in

Child psychologist in Hyderabad

shared by in-sync on 07 Nov 19 - No Cached
  • in-sync on 07 Nov 19
     
    Are you looking for child speech therapy sessions in Hyderabad? The therapeutic intervention is what your kids need. Click here to know more!
teekinghamzat

How Often Can You Donate Blood - Read This Before Donating - 2 views

You will know how often you can donate blood in this article today. I understand that you don't know if there is any risk attached to donating blood to a recipient. Well, one frequently asked q...

donor blood donations

started by teekinghamzat on 26 May 20 no follow-up yet
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