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Nathan Goodyear

Human C-reactive protein and the metabolic syndrom... [Curr Opin Lipidol. 2009] - PubMe... - 0 views

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    elevated CRP linked to increase risk of metabolic syndrome
Nathan Goodyear

C-reactive protein, the metabolic syndrome, and pr... [Circulation. 2004] - PubMed result - 0 views

  • Elevated CRP levels are related to insulin resistance and the presence of the MetS, especially in women
  • both CRP and MetS are independent predictors of new CVD events.
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    elevated CRP helps predict metabolic syndrome and cardiovascular disease
Nathan Goodyear

C-Reactive Protein as a Cardiovascular Risk Factor : More Than an Epiphenomenon? -- Lag... - 0 views

  • CRP constitutes an independent cardiovascular risk factor
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    CRP is an independent marker for future cardiovascular disease
Nathan Goodyear

Interrelationships Among Circulating Interleukin-6, C-Reactive Protein, and Traditional... - 0 views

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    IL-6 and CRP reveal systemic vascular inflammation
Nathan Goodyear

Prospective Study of C-Reactive Protein and the Risk of Future Cardiovascular Events Am... - 0 views

  • CRP is a strong independent risk factor for cardiovascular disease that adds to the predictive value of risk models based on usual factors alone.
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    CRP is marker for cardiovascular risk in women
Nathan Goodyear

Elevated C-reactive protein and homocysteine value... [Atherosclerosis. 2003] - PubMed ... - 0 views

  • This is the first paper to show that CRP values increase with progressive thyroid failure and may count as an additional risk factor for the development of coronary heart disease in hypothyroid patient
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    inflammation, CRP, associated with hypothyroidism
Nathan Goodyear

ScienceDirect - The American Journal of Cardiology : Relation Between C-Reactive Protei... - 0 views

  • these findings indicate that low-grade systemic inflammation and hyperhomocysteinemia were present in participants with high 10-year risk for CAD.
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    elevated homocysteine helps to identify patients with high CAD over 10 years
Nathan Goodyear

Obesity Is a Major Determinant of the Association of C-Reactive Protein Levels and the ... - 0 views

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    obesity increases inflammation and Metabolic syndrome factors
Nathan Goodyear

Low Testosterone and High C-Reactive Protein Concentrations Predict Low Hematocrit in T... - 0 views

  • In these patients, hematocrit is also inversely related to CRP concentration.
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    low T associated with elevated CRP and thus increased cardiovascular risk
Nathan Goodyear

Effect of wine phenolics on cytokine-induced C-reactive protein expression - KAUR - 200... - 0 views

  • Wine phenolics inhibit CRP expression
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    Resveratrol in red wine reduces inflammation
Nathan Goodyear

C-Reactive Protein and All-Cause Mortality in a Large Hospital-Based Cohort - 0 views

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    low sensitivity CRP associated with increased short-term and long-term mortality in hospitalized patients.  Also associated with a 28 fold increase in cancer mortality.
Nathan Goodyear

Testosterone and benign prostatic hyperplasia Jarvis TR, Chughtai B, Kaplan SA, - Asian... - 0 views

  • The prevalence of hypogonadism (often defined as serum testosterone < 300 ng dl−1 ) ranges from 6% [10] to as high as 38%
  • The process of BPH, however, continues as men age and despite the fact their serum testosterone decreases
  • Liu et al. [12] demonstrated that in a group of older males (mean age 59.8 years) that there was not a significant correlation of serum testosterone levels (total, free or bioavailable) with either prostate volume or International Prostate Symptom Score (IPSS)
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  • in eugonadal men, studies have demonstrated that the prostate can increase in volume by approximately 12%
  • There seems to be little doubt that the treatment with testosterone of a young hypogonadal male leads to significant growth of the prostate
  • Behre et al. [22] demonstrated increased prostate volume and prostate-specific antigen (PSA) levels in hypogonadal men
  • Most studies, however, have shown no effect of exogenous androgens on PSA or prostate volume for older hypogonadal males
  • They argue that the prostate is relatively insensitive to changes in androgen concentration at normal levels or in mild hypogonadism because the AR is saturated by androgens and therefore maximal androgen-AR binding is achieved. Conversely, the prostate is very sensitive to changes in androgen levels when testosterone is low
  • saturation model
  • visceral obesity (one of the most significant components of metabolic syndrome) is associated with prostate volume and influences prostate growth during TRT.
  • This hypothesis of inflammation induced LUTS is also argued to be a mechanism for improvement of LUTS with PDE5I
  • The concept, therefore, that treatment with TRT of hypogonadal males with metabolic syndrome might lead to improvement/stabilization of their LUTS, appears to be confirmed in recent work by Francomano et al.
  • There was also an improvement in components of the patient's metabolic syndrome (such as BMI, waist circumference, hemoglobin A1c [HbA1c], insulin sensitivity, and lipid profile) as well as inflammatory markers and C-reactive protein.
  • They concluded that TRT was safe in this group of men, and hypothesize that TRT mitigates the pro-inflammatory factors associated with metabolic syndrome.
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    Authors review the literature behind Testosterone and BPH.  The authors highlight the 4 proposed theories behind BPH: Testosterone, Estrogen, inflammation, and metabolic.   The conclusion is mixed: pointing out that no high level of evidence exists on either side of the debate of Testosterone and BPH.
Nathan Goodyear

JAMA Network | JAMA Internal Medicine | Lipoprotein-Associated Phospholipase A2, High-S... - 0 views

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    increased LP-PLA2 and hsCRP are associated with increased risk of ischemic stroke.
Nathan Goodyear

The Prostate Cancer Patient Had Higher C-Reactive Protein Than BPH Patient - 0 views

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    positive correlation between serum CRP and tumor stage is observed in prostate cancer patients and a correlation was also observed between the rise in CRP and faster progression of the tumor. This result proves that inflammation participates in tumor progression
Nathan Goodyear

C-Reactive Protein in Pneumonia - CHEST - 0 views

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    CRP is useful in determining severity and following treatment of pneumonia
Nathan Goodyear

Increased serum C-reactive protein levels in normal weight women with polycystic ovary ... - 0 views

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    Study doesn't directly link causation, but increased Testosterone in women of normal weight with PCOS associated with increased CRP.
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