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"A new bioprinter developed at a hackerspace can print living cells for less than the cost of an iPod touch. 3-D bioprinters have the potential to change the way medical research is conducted, even print living tissue and replacement organs, but they are expensive and highly specialized. They literally build living structures, like blood vessels or skin tissue, cell by cell, revolutionizing biomedical engineering. Unfortunately, they're expensive, rare, and require a Ph.D. (or two) to operate successfully. Frustrated by their cost and exclusivity, a group of makers at the DIYbio hackerspace BioCurious are developing a system open to anyone with a soldering iron and a serious passion for cell biology."

"The Global Brain can be defined as the distributed intelligence emerging from the Internet. The Global Brain Institute (GBI) was founded in 2012 at the Vrije Universiteit Brussel (VUB) to research this phenomenon. The GBI grew out of the Global Brain Group, an international community of researchers created in 1996, and the Evolution, Complexity and Cognition research group at the VUB."

"At JSTOR Labs, we get up each day with one goal: to shape the future of research and teaching, one project at a time. Working with partner publishers, libraries and labs, we aim to create tools for researchers, teachers and students that are immediately useful - and a little bit magical."

"When the right microorganisms are at work, immune cells involved in the development of autoimmune illnesses like psoriasis, multiple sclerosis and arthritis, can develop anti-inflammatory properties. Scientists at Charité - Universitätsmedizin Berlin and the Institute for Research in Biomedicine, Bellinzona, Switzerland, have now made this discovery. Their work is published in the current issue of the scientific journal Nature*. The scientists were able to prove that particular fungi activate the immune cells involved in the development of certain illnesses, whereas other microorganisms, in particular bacteria that are found naturally on our skin, lend an anti-inflammatory function to them. "This not only demonstrates that the composition of our microflora has a decisive role in the development of chronic illnesses, but also that the key cells causing illness can develop an anti-inflammatory 'twin'," explained Dr. Christina Zielinski, first author of the study."

"Previous research on rhesus macaques discovered that social rank influenced components of the stress response, brain, and immune system. With gene chip technology for measuring the expression of over 6,000 different genes, Tung, Gilad and colleagues at Yerkes, Emory University, and Johns Hopkins looked for the first time in primates at the effects of social rank on genetic function. Comparing 49 different female monkeys of different rank revealed significant changes in the expression of 987 genes, including 112 genes associated with immune system function. The result fits with data in monkeys where low rank and chronic stress lead to compromised immune function, and, more loosely, with human studies linking low socioeconomic status and high social stress to elevated disease risk."

"What they found here was a negative correlation. The MORE serotonin transporters you had, the less likely you were to reject unfair offers. The authors interpret this to mean that people with lower levels of serotonin transporter had a harsher sense of "fairness", than those with higher levels of serotonin transporter, and were more inclined to reject unfair offers. Why could this be the case? The authors looked at the personalities of the individuals. You might think that people with more aggressive personalities (or at least a tendency to get offended) might be more likely to reject unfair offers, but it turned out that this wasn't the case. Instead, it was people with more peaceful personalities, but stronger measures of trust, were more likely to reject the unfair offers. The authors believe that the people with higher trustfulness had higher standards of behavior, and thus were more likely to reject unfair offers, even if the rejected ended up badly for them"

Come work with us Interested in working with researchers from different disciplines within the Harvard, MIT and Broad community and an unique opportunity to participate in world-class research to make an impact on human health? Come work with us! We are looking for a computational biologists to handle data from a wide variety of experimental methods, focusing on next-gen sequencing technologies. Keep Reading...  SCDE is live The Stem Cell Discovery Engine (SCDE) is an integrated platform that allows users to consistently describe, share and compare cancer and tissue stem cell data. It is made up of an online database of curated experiments coupled to a customized instance of the Galaxy analysis engine with tools for gene list manipulation and molecular profile comparisons. The SCDE currently contains more than 50 stem cell-related experiments. Each has been manually curated and encoded using the ISA-Tab standard to ensure the quality of the data and its annotation. Keep Reading...  The Center for Health Bioinformatics at the Harvard School of Public Health provides consults to researchers for the management, integration and contextual analysis of biological high-throughput data. We are a member of the Center for Stem Cell Bioinformatics, the Environmental Statistics and Bioinformatics Core at the Harvard NIEHS Center for Environmental Health and the Genetics & Bioinformatics Consulting group for Harvard Catalyst and work closely with our colleagues in the Department of Biostatistics and the Program in Quantitative Genomics to act as a single point of contact for computational biology,

""We wondered how individuals assess the credibility of other people in simple social interactions," said Read Montague, director of the Human Neuroimaging Laboratory and the Computational Psychiatry Unit at the Virginia Tech Carilion Research Institute, who led the study. "We found a strong correlation between the amygdala and a baseline level of distrust, which may be based on a person's beliefs about the trustworthiness of other people in general, his or her emotional state, and the situation at hand"

"There is a biological story with information. I have been repeating that in a natural environment, a stressor is information. So too much information would be too much stress, exceeding the threshold of antifragility. In medicine, we are discovering the healing powers of fasting, as the avoidance of too much hormonal rushes that come with the ingestion of food. Hormones convey information to the different parts of our system and too much of it confuses our biology. Here again, as with the story of the news received at too high a frequency, too much information becomes harmful. And in Chapter x (on ethics) I will show how too much data (particularly when sterile) causes statistics to be completely meaningless. Now let's add the psychological to this: we are not made to understand the point, so we overreact emotionally to noise. The best solution is to only look at very large changes in data or conditions, never small ones"

ATLAS is a particle physics experiment at the Large Hadron Collider at CERN. The ATLAS detector is searching for new discoveries in the head-on collisions of protons of extraordinarily high energy. ATLAS will learn about the basic forces that have shaped our Universe since the beginning of time and that will determine its fate. Among the possible unknowns are the origin of mass, extra dimensions of space, unification of fundamental forces, and evidence for dark matter candidates in the Universe.

In another study, in which volunteers saw the same pictures while having their brain scanned using MRI, she found that people had a stronger response in the hippocampus and amygdala - areas of the brain associated with fear - when they were shown fearful faces at systole than when they saw them at diastole. In other words, half a heartbeat was all it took for a person to experience a significantly different response to the same scary stimulus.

"Rather, these successful men needed to also be blessed with "zeal and with capacity for hard labour." This study is a first glimpse into those essential qualities described by Galton, helping us map out the individual differences that make it slightly easier for some people to engage in hard labor. These diligent souls seem to get a bit more pleasure from the possibility of reward, but they also seem less sensitive to their inner complainer, that disruptive voice reminding them that minesweeper is more fun than editing, or that the ballgame on television is much more entertaining than their homework. At any given moment, there is a tug of war unfolding in our head, determining whether or not we're willing to put in the effort. This sentence only exists because, for a few minutes at least, I was able to win the war."

""We probably have underestimated the role our microbial flora play in modulating disease risk," says Daniel Rader, a heart disease specialist at the University of Pennsylvania School of Medicine. Rader, who was not involved in the study, says that gut bacteria may not be as big a factor in causing heart disease as diabetes or smoking, but could be important in tipping some people toward sickness. Researchers led by Stanley Hazen, a cardiologist at the Cleveland Clinic, didn't start out to study gut bacteria. In fact, says Hazen, he had "no clue - zero," that intestinal microbes were involved in heart disease. "I'd never even considered it or thought of the concept." Hazen and his colleagues compared blood plasma from healthy people to plasma from people who had had heart attacks, strokes or died to see if substances in the blood could predict who is in danger from heart disease. The researchers found 18 small molecules associated with fat buildup in the arteries. One of the best predictors turned out to be a byproduct made when gut bacteria break down a fat called choline (also known as lecithin). The more of this byproduct, called trimethylamine N-oxide or TMAO, a person or mouse has in the blood, the higher the risk of getting heart disease, the researchers found. Gut bacteria are actually middlemen in TMAO production. The microbes convert lecithin to a gas that smells like rotten fish. Then an enzyme in the liver changes the foul-smelling gas to TMAO."

"The molecule PKR (the double-stranded RNA-activated protein kinase) was originally described as a sensor of viral infections, but its function in the brain was totally unknown," said Dr. Mauro Costa-Mattioli, assistant professor of neuroscience at BCM and senior author of the paper. Since the activity of PKR is altered in a variety of cognitive disorders, Costa-Mattioli and colleagues decided to take a closer look at its role in the mammalian brain. Super memory The authors discovered that mice lacking PKR in the brain have a kind of "super" memory. "

Some argue that these genes bring benefits - mental illness and genius have a long-standing link - but archaeologist Penny Spikins at the University of York, UK, goes further. She believes that mental illness and conditions such as autism persist at such high levels because in the past they were advantageous to humanity. "I think that part of the reason Homo sapiens were so successful is because they were willing to include people with different minds in their society - people with autism or schizophrenia, for example."

"Leah Pyter: Well basically what we know is that patients with cancer have a higher likelihood of also developing depression at some point in their disease progression, so whether that occurred before and is predisposing them to cancer, or it's due to the tumours themselves, or other aspects of having the disease, we don't know. We were only studying right now whether the cancer itself can cause depression. Chris Smith: How could a tumour trigger depression, because a tumour can occur anywhere in the body, therefore at the remote sites in the brain, so how could it trigger changes in brain activity? Leah Pyter: Sure, well what we hypothesized was that the tumours themselves can produce cytokines which has been shown before. Chris Smith: These are inflammatory chemicals that drive the immune system? Leah Pyter: Right, exactly! And there is also a pile of research on how cytokines can access the brain specifically regions of the brain that are associated with depression and anxiety and emotional behaviours, and they can access the brain both tumourally through the blood, or neurally through the vegas nerves. "

A collection of IT training resources at UCLA. LearnIT is your one-stop shop for online IT training resources at UCLA. Please use the buttons on the right under the heading "IT Resources" to log in to the various websites anytime, anywhere.

"If you were a bacterium, the virus M13 might seem innocuous enough. It insinuates more than it invades, setting up shop like a freeloading houseguest, not a killer. Once inside it makes itself at home, eating your food, texting indiscriminately. Recently, however, bioengineers at Stanford have given M13 a bit of a makeover. The researchers, Monica Ortiz, a doctoral candidate in bioengineering, and Drew Endy, PhD, an assistant professor of bioengineering, have parasitized the parasite and harnessed M13's key attributes - its non-lethality and its ability to package and broadcast arbitrary DNA strands - to create what might be termed the biological Internet, or "Bi-Fi." Their findings were published online Sept. 7 in the Journal of Biological Engineering."

Ai Research is a leading artificial intelligence research project. At Ai, we're creating a new form of life. Our expanding web site is an essential part of the emerging global discussion about artificial intelligence. On this website, we showcase the state of the art in pattern-matching conversational machines, demonstrated by Alan, and in reinforcement learning algorithms, demonstrated by HAL. Use our forums, original papers, online labs, demos and links to explore what's happening both at Ai (the project) and in AI (the field).

Dr Simon Archer and his team at Surrey University were particularly interested in looking at the genes that were switched on or off in our volunteers by changes in the amount that we had made them sleep. "We found that overall there were around 500 genes that were affected," Archer explained. "Some which were going up, and some which were going down." What they discovered is that when the volunteers cut back from seven-and-a-half to six-and-a-half hours' sleep a night, genes that are associated with processes like inflammation, immune response and response to stress became more active. The team also saw increases in the activity of genes associated with diabetes and risk of cancer. The reverse happened when the volunteers added an hour of sleep. So the clear message from this experiment was that if you are getting less than seven hours' sleep a night and can alter your sleep habits, even just a little bit, it could make you healthier